Detailed information NTG0960002

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: WHL52_RS19170
• Genome accession: NZ_CP149576
• Coordinates: 3640602..3641759 (-)
• Length: 385 a.a.
• NCBI ID: WP_003227983.1
• Uniprot ID: A0A199WDV9
• Organism: Bacillus subtilis strain DSM 10
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3635602..3646759

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WHL52_RS19140	yvyF	3635855..3636274 (-)	420	WP_003227995.1	TIGR03826 family flagellar region protein	-
WHL52_RS19145	comFC	3636348..3637070 (-)	723	WP_003227991.1	comF operon protein ComFC	Machinery gene
WHL52_RS19150	comFB	3637034..3637330 (-)	297	WP_003227989.1	late competence protein ComFB	-
WHL52_RS19155	comFA	3637390..3638781 (-)	1392	WP_003243962.1	ATP-dependent helicase ComFA	Machinery gene
WHL52_RS19160	fakBA	3638887..3639732 (-)	846	WP_003244125.1	DegV family protein	-
WHL52_RS19165	degU	3639830..3640519 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
WHL52_RS19170	degS	3640602..3641759 (-)	1158	WP_003227983.1	two-component sensor histidine kinase DegS	Regulator
WHL52_RS19175	yvyE	3641976..3642629 (+)	654	WP_003227979.1	YigZ family protein	-
WHL52_RS19180	tagV	3642629..3643804 (+)	1176	WP_003244117.1	polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagV	-
WHL52_RS19185	tagO	3643877..3644953 (-)	1077	WP_003227975.1	MraY family glycosyltransferase	-
WHL52_RS19190	tuaH	3645098..3646291 (-)	1194	WP_003243252.1	glycosyltransferase family 1 protein	-

Sequence

Protein

• Length: 385 a.a.
• Molecular weight: 44957.76 Da
• Isoelectric Point: 6.2957

>NTDB_id=960002 WHL52_RS19170 WP_003227983.1 3640602..3641759(-) (degS) [Bacillus subtilis strain DSM 10]
MNKTKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVQTRHARNRLSEVSR
NFHRFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLREVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGAEDGFQEIKNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGETEDQRLAPQFEVALFRLAQEAVSNALKHSESEEITVKVEI
TKDFVILMIKDNGKGFDLKEAKEKKNKSFGLLGMKERVDLLEGTMTIDSKIGLGTFIMIKVPLSL

Nucleotide

• Length: 1158 bp

>NTDB_id=960002 WHL52_RS19170 WP_003227983.1 3640602..3641759(-) (degS) [Bacillus subtilis strain DSM 10]
ATGAATAAAACAAAGATGGATTCCAAAGTGCTGGATTCTATTTTGATGAAGATGCTGAAAACCGTTGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGGGAGCAGTCACGCCAGCAGTATGAACAGCTGGTCGAAGAACTGAAACAAATTAAACAGCAGG
TGTATGAAGTGATTGAGCTTGGCGATAAACTTGAAGTGCAAACTCGCCATGCGAGAAACCGTTTATCCGAGGTCAGCCGT
AATTTTCATAGATTCAGTGAAGAGGAAATCCGCAATGCTTATGAAAAAGCCCATAAGCTGCAGGTAGAATTGACGATGAT
CCAGCAGCGTGAGAAGCAATTGCGCGAACGGCGGGACGATTTGGAGCGCAGATTGCTAGGGCTTCAGGAAATCATTGAGC
GGTCAGAATCATTAGTAAGCCAAATTACAGTTGTGCTCAACTACTTGAATCAGGATTTGCGCGAAGTTGGACTGCTTCTT
GCTGATGCTCAGGCAAAACAGGATTTCGGCTTAAGAATTATTGAGGCGCAGGAAGAAGAGCGAAAAAGAGTCTCAAGAGA
AATCCATGACGGACCCGCTCAAATGCTGGCGAATGTTATGATGAGATCGGAATTAATCGAGCGGATTTTCCGTGACCGGG
GCGCAGAGGACGGATTCCAAGAAATTAAAAATCTCCGCCAAAATGTTCGGAATGCCCTTTACGAAGTGAGAAGGATTATA
TATGATTTAAGACCGATGGCCCTTGATGACCTAGGCCTGATTCCAACTTTAAGAAAATATCTATATACAACCGAGGAATA
TAACGGGAAGGTCAAAATACATTTTCAGTGCATTGGAGAAACAGAGGATCAGAGGCTAGCGCCTCAGTTTGAGGTTGCGC
TCTTCAGGCTCGCACAGGAAGCTGTGTCTAATGCGCTAAAGCATTCTGAATCTGAAGAAATTACAGTCAAAGTTGAGATC
ACAAAGGATTTTGTGATTTTAATGATAAAAGATAACGGTAAAGGGTTCGACCTGAAGGAAGCGAAAGAGAAGAAAAACAA
ATCATTCGGCTTGCTGGGCATGAAAGAAAGAGTAGATTTATTGGAAGGAACGATGACAATAGATTCGAAAATAGGTCTTG
GGACATTTATTATGATTAAGGTTCCGTTATCTCTTTGA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (180-248)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

3D structure

• AlphaFold DB: A0A199WDV9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	100	100	1