Detailed information NTG0959541

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: WJ060_RS10190
• Genome accession: NZ_CP149492
• Coordinates: 2055130..2056173 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BPH2947
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2050130..2061173

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WJ060_RS10160 (WJ060_10145)	-	2050548..2051804 (-)	1257	WP_001795438.1	aminopeptidase	-
WJ060_RS10165 (WJ060_10150)	-	2051807..2052007 (-)	201	WP_000180461.1	DUF1128 family protein	-
WJ060_RS10170 (WJ060_10155)	-	2052154..2052618 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
WJ060_RS10175 (WJ060_10160)	-	2052625..2052900 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
WJ060_RS10180 (WJ060_10165)	-	2053178..2054395 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
WJ060_RS10185 (WJ060_10170)	vraR	2054511..2055140 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
WJ060_RS10190 (WJ060_10175)	vraS	2055130..2056173 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
WJ060_RS10195 (WJ060_10180)	liaF	2056170..2056871 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
WJ060_RS10200 (WJ060_10185)	-	2056886..2057272 (-)	387	WP_001110179.1	hypothetical protein	-
WJ060_RS10205 (WJ060_10190)	map	2057489..2058247 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
WJ060_RS10210 (WJ060_10195)	-	2058834..2059820 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
WJ060_RS10215 (WJ060_10200)	-	2060251..2060664 (-)	414	WP_001549145.1	hypothetical protein	-
WJ060_RS10220 (WJ060_10205)	-	2060693..2060803 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=959541 WJ060_RS10190 WP_001017131.1 2055130..2056173(-) (vraS) [Staphylococcus aureus strain BPH2947]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=959541 WJ060_RS10190 WP_001017131.1 2055130..2056173(-) (vraS) [Staphylococcus aureus strain BPH2947]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1