Detailed information    

insolico Bioinformatically predicted

Overview


Name   comS   Type   Regulator
Locus tag   WJ062_RS00340 Genome accession   NZ_CP149486
Coordinates   53548..53643 (+) Length   31 a.a.
NCBI ID   WP_198462994.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain EMM113     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context


Location: 48548..58643
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WJ062_RS00320 (WJ062_00315) purK 48617..49690 (+) 1074 WP_168639781.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  WJ062_RS00325 (WJ062_00320) - 49692..51110 (+) 1419 WP_109821005.1 hypothetical protein -
  WJ062_RS00330 (WJ062_00325) purB 51130..52422 (+) 1293 WP_030127622.1 adenylosuccinate lyase -
  WJ062_RS00335 (WJ062_00330) comR 52553..53464 (+) 912 WP_136119936.1 transcriptional regulator Rgg4/ComR Regulator
  WJ062_RS00340 comS 53548..53643 (+) 96 WP_198462994.1 quorum-sensing system DWW-type pheromone Regulator
  WJ062_RS00345 (WJ062_00335) ruvB 53690..54688 (+) 999 WP_002987726.1 Holliday junction branch migration DNA helicase RuvB -
  WJ062_RS00350 (WJ062_00340) - 54826..55263 (+) 438 WP_002994668.1 low molecular weight protein-tyrosine-phosphatase -
  WJ062_RS00355 (WJ062_00345) - 55286..55687 (+) 402 WP_002986671.1 MORN repeat-containing protein -
  WJ062_RS00360 (WJ062_00350) - 55684..57459 (+) 1776 WP_011284411.1 acyltransferase family protein -

Sequence


Protein


Download         Length: 31 a.a.        Molecular weight: 3857.66 Da        Isoelectric Point: 10.0436

>NTDB_id=959407 WJ062_RS00340 WP_198462994.1 53548..53643(+) (comS) [Streptococcus pyogenes strain EMM113]
MLKKYKYYFIFAALLSFKVVQELSAVDWWRL

Nucleotide


Download         Length: 96 bp        

>NTDB_id=959407 WJ062_RS00340 WP_198462994.1 53548..53643(+) (comS) [Streptococcus pyogenes strain EMM113]
ATGTTAAAAAAGTATAAGTACTATTTTATATTCGCAGCTCTACTATCTTTTAAAGTAGTTCAAGAGCTTAGTGCTGTTGA
CTGGTGGCGATTATAA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comS Streptococcus pyogenes MGAS8232

100

100

1

  comS Streptococcus pyogenes MGAS315

45.161

100

0.452