Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   AABA19_RS01980 Genome accession   NZ_AP028609
Coordinates   377428..378060 (+) Length   210 a.a.
NCBI ID   WP_000698439.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain Sep4     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 372428..383060
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AABA19_RS01955 (TKY121806_03770) mvaD 372706..373659 (+) 954 WP_000373455.1 diphosphomevalonate decarboxylase -
  AABA19_RS01960 (TKY121806_03780) - 373646..374653 (+) 1008 WP_000562413.1 phosphomevalonate kinase -
  AABA19_RS01965 (TKY121806_03790) fni 374637..375647 (+) 1011 WP_000210618.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  AABA19_RS01970 (TKY121806_03800) liaF 375724..376422 (+) 699 WP_001224640.1 cell wall-active antibiotics response protein LiaF -
  AABA19_RS01975 (TKY121806_03810) - 376419..377414 (+) 996 WP_000743671.1 sensor histidine kinase -
  AABA19_RS01980 (TKY121806_03820) vraR 377428..378060 (+) 633 WP_000698439.1 response regulator transcription factor Regulator
  AABA19_RS01985 - 378136..378830 (+) 695 Protein_389 DNA alkylation repair protein -
  AABA19_RS01990 (TKY121806_03850) - 378980..379219 (+) 240 WP_000754502.1 hypothetical protein -
  AABA19_RS01995 (TKY121806_03860) cbpG 379300..380133 (+) 834 WP_001828941.1 choline-binding protein CbpG -
  AABA19_RS02000 (TKY121806_03870) cbpF 380152..381174 (+) 1023 WP_000771062.1 choline-binding protein CbpF -
  AABA19_RS02005 - 381302..382650 (-) 1349 Protein_393 IS3 family transposase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23579.06 Da        Isoelectric Point: 4.5145

>NTDB_id=95927 AABA19_RS01980 WP_000698439.1 377428..378060(+) (vraR) [Streptococcus pneumoniae strain Sep4]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNYMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=95927 AABA19_RS01980 WP_000698439.1 377428..378060(+) (vraR) [Streptococcus pneumoniae strain Sep4]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGTTTGGGTTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGAATTGACGCGACCTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCATGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGATGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATTATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAATATTCTTGCCAAACT
TGAAGTCAGCGATCGTACCCAGGCGGCTGTCTATGCCTTTCAGCACCATTTGGTGGGGCAAGAGGAGTTTTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-114)

Bacterial regulatory proteins, luxR family (GerE)

(145-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

37.668

100

0.4