Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ACI1GX_RS01465 Genome accession   NZ_CP173358
Coordinates   310244..312076 (+) Length   610 a.a.
NCBI ID   WP_012262755.1    Uniprot ID   B0BT25
Organism   Actinobacillus pleuropneumoniae strain APL2305225E     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 305244..317076
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACI1GX_RS01440 (ACI1GX_01440) - 305253..306149 (-) 897 WP_005596167.1 metal ABC transporter substrate-binding protein -
  ACI1GX_RS01445 (ACI1GX_01445) - 306216..306551 (-) 336 WP_012478314.1 TusE/DsrC/DsvC family sulfur relay protein -
  ACI1GX_RS01450 (ACI1GX_01450) - 306603..307268 (-) 666 WP_005606991.1 Bax inhibitor-1 family protein -
  ACI1GX_RS01455 (ACI1GX_01455) pgsA 307450..308001 (+) 552 WP_005619923.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ACI1GX_RS01460 (ACI1GX_01460) - 308121..310091 (+) 1971 WP_005596175.1 TonB-dependent receptor domain-containing protein -
  ACI1GX_RS01465 (ACI1GX_01465) uvrC 310244..312076 (+) 1833 WP_012262755.1 excinuclease ABC subunit UvrC Machinery gene
  ACI1GX_RS01470 (ACI1GX_01470) - 312145..312897 (+) 753 WP_012262756.1 TatD family hydrolase -
  ACI1GX_RS01475 (ACI1GX_01475) rep 313034..315052 (-) 2019 WP_012262757.1 DNA helicase Rep -
  ACI1GX_RS01480 (ACI1GX_01480) potA 315386..316501 (+) 1116 WP_005600350.1 spermidine/putrescine ABC transporter ATP-binding protein PotA -

Sequence

Protein


Download         Length: 610 a.a.        Molecular weight: 69167.00 Da        Isoelectric Point: 8.9088

>NTDB_id=958142 ACI1GX_RS01465 WP_012262755.1 310244..312076(+) (uvrC) [Actinobacillus pleuropneumoniae strain APL2305225E]
MFDAKAFLADVPHLPGVYRMYDAKNTIIYVGKAKDLKKRLSSYFRSQLASKKTEALVANIHHIETTITHSETEALLLEHN
YIKENQPKYNVLLRDDKSYPYILLTKHQHPRITSFRGSKKVAGEYFGPYPNAGAVRETLNLLQKLFPIRQCEDSYYKNRS
RPCLQYQIGRCLAPCVESYYSQAEYDNQVNLVRLFLQGKDGQVIEHLVQKMENAAQELDFEAAARFRDQIQSVRAVQEKQ
FVSNERLDDLDIISIAYQHGIACVHILFVRHGKVLGNRSYFPKVPNNTDLSELADTFVGQFYLQMNQHRTIPNQIIIDQP
LSESAALADVLSEQAGHKVSIADKNIRGDKSRYLALAKTNAEAALTLQLKQDTHIRQRYDSLKTLLNLAEIKRMECFDIS
HTMGNQTVASCVVFDENGPLKSDYRRFNIEGITGGDDYAAMEQALLKRYSRHLEEEKIPDIIFIDGGKGQLNRALETFAS
LNVSWDKRKPLLIGVAKGVERKAGLETLLISKWDKEIHLPPDSPALHLIQHIRDESHNHAITGHRKKRQKAFTESGLESI
AGVGAKRRQALLKYLGGMQGVKAATLEEIQSVPGISKQLAEVIFDTLQHS

Nucleotide


Download         Length: 1833 bp        

>NTDB_id=958142 ACI1GX_RS01465 WP_012262755.1 310244..312076(+) (uvrC) [Actinobacillus pleuropneumoniae strain APL2305225E]
ATGTTTGATGCCAAAGCCTTTCTTGCCGATGTTCCTCATCTTCCCGGTGTTTATCGTATGTATGATGCGAAAAATACTAT
TATCTATGTCGGTAAAGCCAAAGATCTCAAAAAGCGTTTATCCAGTTATTTTCGTAGCCAACTCGCCAGTAAGAAAACCG
AGGCGTTAGTCGCTAACATTCATCATATCGAAACCACGATTACCCATTCGGAAACGGAAGCGTTACTACTTGAACATAAT
TACATTAAAGAGAATCAGCCGAAGTACAACGTGCTTTTGCGTGATGATAAATCCTATCCGTATATTTTACTCACAAAGCA
TCAACATCCCCGAATTACTTCGTTTCGTGGTAGTAAAAAAGTTGCCGGTGAATATTTTGGTCCGTATCCGAATGCAGGTG
CAGTGCGTGAAACGCTAAACTTGCTGCAAAAACTGTTTCCGATTCGCCAATGTGAAGACAGCTACTATAAAAATCGTTCT
CGCCCTTGTTTGCAATACCAAATTGGGCGTTGTCTTGCCCCTTGTGTAGAAAGTTATTACTCACAAGCGGAATATGATAA
CCAAGTAAATTTAGTCCGCTTATTTTTACAAGGTAAAGACGGACAAGTGATTGAGCATTTGGTACAAAAAATGGAAAACG
CTGCGCAAGAGCTGGATTTTGAAGCGGCGGCTCGTTTTCGCGATCAGATCCAATCGGTACGAGCGGTGCAAGAAAAACAA
TTTGTCTCTAACGAACGTTTGGATGATTTGGATATTATTTCGATCGCTTATCAACACGGTATTGCTTGCGTACATATTTT
ATTTGTGCGTCACGGTAAGGTATTGGGTAATCGTTCCTATTTTCCTAAAGTGCCGAACAATACCGATTTAAGCGAGTTGG
CGGATACCTTTGTCGGTCAATTTTATCTACAGATGAACCAACATCGCACGATACCAAATCAAATTATTATCGATCAGCCG
TTAAGTGAATCGGCGGCATTAGCTGATGTGCTGTCCGAACAAGCGGGGCATAAAGTCAGTATTGCCGATAAAAATATTCG
TGGCGATAAAAGCCGCTATTTGGCATTGGCGAAAACCAATGCGGAAGCGGCACTTACTTTACAACTTAAACAAGATACGC
ATATTCGCCAGCGTTATGATTCGCTGAAAACATTACTTAATTTAGCGGAAATCAAGCGAATGGAGTGTTTCGATATTTCT
CACACAATGGGTAATCAAACGGTAGCTTCTTGCGTAGTGTTTGATGAAAATGGACCGTTAAAATCGGATTACCGCCGTTT
TAATATTGAAGGTATTACCGGCGGTGATGATTATGCGGCAATGGAACAAGCCTTATTAAAGCGTTATAGCCGTCATTTAG
AAGAAGAAAAAATTCCGGATATTATTTTTATTGATGGTGGGAAAGGGCAGCTTAATCGAGCGTTGGAAACTTTTGCTTCA
TTAAATGTCAGTTGGGATAAACGTAAACCGCTGTTAATTGGTGTGGCAAAAGGTGTGGAAAGAAAAGCCGGTTTAGAAAC
TTTGCTGATCAGTAAGTGGGATAAGGAAATTCACTTACCGCCGGACAGTCCCGCACTACATTTGATTCAACATATTCGTG
ACGAATCGCATAATCACGCAATAACCGGACACCGTAAAAAGCGCCAAAAAGCCTTTACGGAAAGTGGCTTAGAATCAATC
GCCGGTGTTGGAGCAAAACGTCGCCAAGCGTTACTGAAATACCTCGGCGGAATGCAGGGCGTGAAAGCCGCAACTTTAGA
AGAAATTCAATCCGTACCCGGTATTTCAAAGCAACTTGCCGAAGTGATTTTTGATACGTTACAGCATAGCTAA

Domains

Predicted by InterProScan.

GIY-YIG catalytic domain (GIY-YIG)

(15-90)

UvrB/uvrC motif (UVR)

(202-235)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-541)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B0BT25

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

37.891

99.508

0.377
  uvrC Streptococcus pneumoniae R6

37.562

99.508

0.374
  uvrC Streptococcus pneumoniae D39

37.562

99.508

0.374