Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   AABA07_RS01820 Genome accession   NZ_AP028608
Coordinates   365430..366062 (+) Length   210 a.a.
NCBI ID   WP_000698434.1    Uniprot ID   Q9S1J7
Organism   Streptococcus pneumoniae strain Sep3     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 360430..371062
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AABA07_RS01795 (TKY120829_03570) mvaD 360707..361660 (+) 954 WP_000373461.1 diphosphomevalonate decarboxylase -
  AABA07_RS01800 (TKY120829_03580) - 361647..362654 (+) 1008 WP_000562422.1 phosphomevalonate kinase -
  AABA07_RS01805 (TKY120829_03590) fni 362638..363648 (+) 1011 WP_000210619.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  AABA07_RS01810 (TKY120829_03600) liaF 363726..364424 (+) 699 WP_001224637.1 cell wall-active antibiotics response protein LiaF -
  AABA07_RS01815 (TKY120829_03610) - 364421..365416 (+) 996 WP_000743683.1 sensor histidine kinase -
  AABA07_RS01820 (TKY120829_03620) vraR 365430..366062 (+) 633 WP_000698434.1 response regulator transcription factor Regulator
  AABA07_RS01825 - 366138..366832 (+) 695 Protein_356 DNA alkylation repair protein -
  AABA07_RS01830 (TKY120829_03650) - 366982..367221 (+) 240 WP_000754502.1 hypothetical protein -
  AABA07_RS01835 (TKY120829_03660) cbpG 367302..367896 (+) 595 Protein_358 choline-binding protein CbpG -
  AABA07_RS01840 (TKY120829_03670) - 368198..368590 (+) 393 WP_000378119.1 tyrosine-type recombinase/integrase -
  AABA07_RS01845 (TKY120829_03680) tig 368751..370034 (+) 1284 WP_000116466.1 trigger factor -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23553.03 Da        Isoelectric Point: 4.5791

>NTDB_id=95809 AABA07_RS01820 WP_000698434.1 365430..366062(+) (vraR) [Streptococcus pneumoniae strain Sep3]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=95809 AABA07_RS01820 WP_000698434.1 365430..366062(+) (vraR) [Streptococcus pneumoniae strain Sep3]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGTTTGGGTTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGGATTGACGCGACTTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCATGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGATGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAATATTCTTGCCAAACT
TGAAGTCAGCGATCGTACCCAGGCGGCTGTCTATGCCTTTCAGCACCATTTGGTGGGGCAAGAGGAGTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9S1J7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41