Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   ACIX3D_RS06950 Genome accession   NZ_CP173318
Coordinates   1509201..1510460 (-) Length   419 a.a.
NCBI ID   WP_005598324.1    Uniprot ID   A0ABM6X5K8
Organism   Actinobacillus pleuropneumoniae strain APL2210214E     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1504201..1515460
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACIX3D_RS06920 (ACIX3D_06925) gltX 1505515..1506954 (+) 1440 WP_005598316.1 glutamate--tRNA ligase -
  ACIX3D_RS06930 (ACIX3D_06935) yefM 1507291..1507542 (+) 252 WP_005598318.1 YoeB-YefM toxin-antitoxin system antitoxin YefM -
  ACIX3D_RS06935 (ACIX3D_06940) - 1507539..1507799 (+) 261 WP_005605064.1 Txe/YoeB family addiction module toxin -
  ACIX3D_RS06940 (ACIX3D_06945) - 1507958..1508125 (-) 168 WP_005598320.1 Trm112 family protein -
  ACIX3D_RS06945 (ACIX3D_06950) lpxK 1508127..1509107 (-) 981 WP_005598322.1 tetraacyldisaccharide 4'-kinase -
  ACIX3D_RS06950 (ACIX3D_06955) clpX 1509201..1510460 (-) 1260 WP_005598324.1 ATP-dependent protease ATP-binding subunit ClpX Regulator
  ACIX3D_RS06955 (ACIX3D_06960) clpP 1510460..1511050 (-) 591 WP_005598326.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP -
  ACIX3D_RS06960 (ACIX3D_06965) - 1511172..1511564 (+) 393 WP_005620423.1 SufE family protein -
  ACIX3D_RS06975 (ACIX3D_06980) dnaQ 1511923..1512696 (-) 774 WP_005598329.1 DNA polymerase III subunit epsilon -
  ACIX3D_RS06980 (ACIX3D_06985) ettA 1512783..1514453 (-) 1671 WP_043991868.1 energy-dependent translational throttle protein EttA -
  ACIX3D_RS06985 (ACIX3D_06990) - 1514618..1514956 (+) 339 WP_005598331.1 carboxymuconolactone decarboxylase family protein -
  ACIX3D_RS06990 (ACIX3D_06995) - 1514949..1515317 (+) 369 WP_005598332.1 rhodanese-like domain-containing protein -

Sequence

Protein


Download         Length: 419 a.a.        Molecular weight: 46361.06 Da        Isoelectric Point: 5.1999

>NTDB_id=958063 ACIX3D_RS06950 WP_005598324.1 1509201..1510460(-) (clpX) [Actinobacillus pleuropneumoniae strain APL2210214E]
MANFEKEPHCSFCGKRRTEVDQLVEGTEGYICNHCIEESYALLNGEEEPLIDEKQDEQKFFENVPTPHEINAHLDEYVIG
QEHAKKVLSVAVYNHYKRLRNALSGHKETNGVELGKSNILLIGPTGSGKTLLAETLARRLNVPFAVADATTLTQAGYVGE
DVENVIQKLLMKCDFDAEQAERGIVFIDEIDKITRKSESPSITRDVSGEGVQQALLKLIEGTVANINPQGSRKHPKGETI
PVDTSKILFICGGAFAGLDKIVEARSNKQGGIGFGAELKKDKEREDLTELFKQVEPEDLVKFGLIPELIGRLPVVTPLQE
LDEEALIQILTEPKNAIIKQYQALFQMEGVELKFTKEALIAIAQKSISRKTGARGLRSIVENLLLDTMYNLPTLKAEKNV
KKVTVGKGCVENGDKPKVE

Nucleotide


Download         Length: 1260 bp        

>NTDB_id=958063 ACIX3D_RS06950 WP_005598324.1 1509201..1510460(-) (clpX) [Actinobacillus pleuropneumoniae strain APL2210214E]
ATGGCAAATTTCGAGAAAGAACCGCATTGTAGTTTTTGTGGTAAAAGACGTACCGAAGTTGATCAACTGGTAGAAGGTAC
GGAAGGTTATATCTGTAATCACTGTATTGAAGAGTCTTACGCATTGTTAAACGGCGAAGAAGAACCGTTAATCGATGAAA
AACAGGATGAACAGAAGTTTTTTGAAAATGTGCCGACGCCACACGAGATCAATGCGCATTTAGATGAGTATGTTATCGGT
CAAGAGCATGCGAAAAAAGTGTTGTCCGTAGCGGTTTATAACCACTATAAACGTTTACGTAACGCGCTTTCCGGTCATAA
AGAAACCAACGGCGTAGAGTTGGGTAAAAGTAACATTTTATTAATCGGCCCGACCGGTAGCGGTAAAACCTTATTGGCGG
AAACGTTAGCGCGCCGTTTAAACGTACCCTTTGCGGTTGCGGATGCAACCACGCTGACGCAAGCCGGTTATGTCGGTGAA
GACGTAGAAAACGTGATTCAAAAATTACTGATGAAATGTGATTTTGATGCGGAACAAGCGGAACGCGGTATCGTCTTTAT
TGATGAGATTGACAAAATCACCCGTAAGTCGGAAAGCCCGTCGATTACCCGCGACGTATCCGGTGAAGGCGTGCAACAGG
CGTTATTAAAATTAATCGAAGGCACGGTAGCGAATATCAACCCGCAAGGCAGCCGTAAGCACCCGAAAGGCGAAACGATT
CCGGTCGATACCTCTAAAATCCTCTTTATTTGCGGCGGAGCGTTTGCCGGTTTAGATAAGATTGTCGAGGCTCGTAGTAA
CAAGCAAGGCGGAATCGGTTTTGGCGCAGAATTGAAAAAAGATAAAGAACGTGAAGATCTCACCGAGTTATTCAAACAAG
TTGAGCCGGAAGACTTGGTTAAATTCGGTTTAATTCCGGAGCTTATCGGTCGATTACCGGTTGTGACTCCGTTACAAGAA
CTGGATGAAGAAGCGTTAATTCAAATTTTAACCGAACCGAAAAATGCGATTATCAAGCAATATCAAGCATTATTCCAAAT
GGAAGGTGTTGAGCTGAAATTTACCAAAGAGGCGTTAATTGCAATCGCGCAGAAATCTATTTCACGCAAAACCGGTGCAC
GCGGTTTACGCTCGATTGTTGAGAATCTACTGTTAGATACGATGTATAACTTGCCGACACTTAAAGCAGAGAAAAATGTG
AAAAAAGTGACGGTTGGCAAAGGTTGTGTTGAAAACGGCGATAAGCCGAAAGTAGAGTAA

Domains

Predicted by InterProScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(9-44)

AAA domain (Cdc48 subfamily) (AAA_2)

(116-314)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(321-403)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

54.964

98.568

0.542
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.186

92.601

0.52