Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ACIUM8_RS01460 Genome accession   NZ_CP173317
Coordinates   314197..316029 (+) Length   610 a.a.
NCBI ID   WP_005596177.1    Uniprot ID   A0ABM6X0X3
Organism   Actinobacillus pleuropneumoniae strain APL2210213E     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 309197..321029
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACIUM8_RS01435 (ACIUM8_01435) - 309206..310102 (-) 897 WP_005596167.1 metal ABC transporter substrate-binding protein -
  ACIUM8_RS01440 (ACIUM8_01440) - 310169..310504 (-) 336 WP_012478314.1 TusE/DsrC/DsvC family sulfur relay protein -
  ACIUM8_RS01445 (ACIUM8_01445) - 310556..311221 (-) 666 WP_005596172.1 Bax inhibitor-1 family protein -
  ACIUM8_RS01450 (ACIUM8_01450) pgsA 311403..311954 (+) 552 WP_005618995.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ACIUM8_RS01455 (ACIUM8_01455) - 312074..314044 (+) 1971 WP_005596175.1 TonB-dependent receptor domain-containing protein -
  ACIUM8_RS01460 (ACIUM8_01460) uvrC 314197..316029 (+) 1833 WP_005596177.1 excinuclease ABC subunit UvrC Machinery gene
  ACIUM8_RS01465 (ACIUM8_01465) - 316098..316850 (+) 753 WP_005596181.1 TatD family hydrolase -
  ACIUM8_RS01470 (ACIUM8_01470) rep 316987..319005 (-) 2019 WP_005596184.1 DNA helicase Rep -
  ACIUM8_RS01475 (ACIUM8_01475) potA 319339..320454 (+) 1116 WP_005596185.1 spermidine/putrescine ABC transporter ATP-binding protein PotA -

Sequence

Protein


Download         Length: 610 a.a.        Molecular weight: 69125.97 Da        Isoelectric Point: 9.1307

>NTDB_id=957976 ACIUM8_RS01460 WP_005596177.1 314197..316029(+) (uvrC) [Actinobacillus pleuropneumoniae strain APL2210213E]
MFDAKAFLADVPHLPGVYRMYDAKNTIIYVGKAKDLKKRLSSYFRSQLASKKTEALVANIHHIETTITHSETEALLLEHN
YIKENQPKYNVLLRDDKSYPYILLTKHQHPRITSFRGSKKVAGEYFGPYPNAGAVRETLNLLQKLFPIRQCEDSYYKNRS
RPCLQYQIGRCLAPCVEGYYSQAEYDNQVNLVRLFLQGKDGQVVEHLVQKMENAAQELDFEAAARFRDQIQSVRAVQEKQ
FVSNERLDDLDIISIAYQHGIACVHILFVRHGKVLGNRSYFPKVPNNTDLSELADTFVGQFYLQMNQHRTIPNQIIIDQS
LSEVTALANVLSEQAGHKVSIADKNIRGDKSRYLALAKTNAEAALTLQLKQDTHIRQRYDSLKALLNLAEIKRMECFDIS
HTMGNQTVASCVVFDKNGPLKSDYRRFNIEGITGGDDYAAIEQALLKRYDRNLEEEKIPDIIFIDGGKGQLNRALETFTS
LNVSWDKRKPLLVGVAKGVERKAGLETLLISKWDKEIHLPPDSPALHLIQHIRDESHNHAITGHRKKRQKAFTESGLESI
AGVGAKRRQALLKYLGGMQGVKAATLEEIQSVPGISKQLAEVIFDTLQHS

Nucleotide


Download         Length: 1833 bp        

>NTDB_id=957976 ACIUM8_RS01460 WP_005596177.1 314197..316029(+) (uvrC) [Actinobacillus pleuropneumoniae strain APL2210213E]
ATGTTTGATGCCAAAGCCTTTCTTGCCGATGTTCCTCATCTCCCCGGTGTTTACCGTATGTATGATGCGAAAAATACTAT
TATCTATGTCGGTAAAGCCAAAGATCTTAAAAAACGCTTATCCAGTTATTTTCGTAGCCAACTTGCCAGTAAGAAAACCG
AGGCGTTAGTCGCTAACATTCATCATATCGAAACCACGATTACCCATTCGGAAACGGAAGCGTTACTACTTGAACATAAT
TACATTAAAGAGAATCAGCCGAAGTACAACGTGCTTTTGCGTGACGATAAATCCTATCCGTATATTTTACTCACAAAGCA
TCAACATCCCCGAATTACTTCGTTTCGTGGTAGTAAAAAAGTTGCCGGTGAATATTTTGGCCCGTATCCGAATGCAGGTG
CAGTGCGTGAAACGCTAAACTTGCTGCAAAAACTGTTTCCGATTCGCCAATGTGAAGACAGCTACTATAAAAATCGTTCT
CGCCCTTGTTTGCAATACCAAATTGGGCGTTGTCTTGCCCCTTGTGTAGAAGGTTATTACTCACAAGCGGAATATGATAA
CCAAGTAAATTTAGTCCGTTTGTTTTTACAAGGTAAAGACGGACAAGTGGTTGAGCATTTGGTACAAAAAATGGAAAACG
CTGCGCAAGAGCTGGATTTTGAAGCGGCGGCTCGTTTTCGCGATCAGATCCAATCGGTACGAGCGGTGCAAGAAAAACAA
TTTGTCTCTAACGAACGTTTGGATGATTTGGATATTATTTCGATCGCTTATCAACACGGTATTGCTTGCGTACATATTTT
ATTTGTGCGTCACGGTAAGGTATTGGGTAATCGTTCCTATTTTCCTAAAGTGCCGAACAATACCGATTTAAGCGAGTTGG
CGGATACCTTTGTCGGTCAGTTTTATTTACAAATGAACCAACATCGCACGATACCGAATCAAATTATTATCGATCAGTCG
TTAAGTGAAGTGACTGCATTAGCTAATGTGCTGTCCGAACAAGCGGGGCATAAAGTCAGTATTGCCGATAAAAATATTCG
TGGCGATAAAAGCCGCTATTTGGCATTAGCAAAAACCAATGCGGAAGCCGCGCTTACTTTGCAACTTAAACAAGATACGC
ATATTCGTCAGCGTTATGATTCGCTCAAGGCATTACTCAATTTAGCGGAAATCAAGCGAATGGAGTGTTTCGATATTTCT
CACACAATGGGTAATCAAACGGTAGCTTCTTGTGTCGTATTTGATAAAAATGGGCCGCTAAAATCGGATTACCGCCGTTT
TAATATTGAAGGTATTACCGGTGGTGATGACTATGCGGCAATAGAACAAGCCTTATTAAAACGTTATGACCGCAATTTAG
AAGAAGAAAAAATTCCGGATATTATTTTTATTGATGGTGGGAAAGGTCAGCTGAATCGAGCGTTGGAAACCTTTACTTCG
TTAAATGTCAGTTGGGATAAGCGCAAACCGTTGTTAGTTGGTGTGGCGAAAGGAGTAGAGCGAAAAGCCGGTTTAGAAAC
TTTATTGATCAGCAAATGGGATAAGGAAATTCACTTACCGCCGGACAGTCCCGCACTACATTTGATTCAACATATTCGTG
ACGAATCGCATAATCACGCAATAACCGGACACCGTAAAAAGCGCCAAAAAGCCTTTACGGAAAGTGGCTTAGAATCAATC
GCCGGTGTTGGAGCAAAACGTCGCCAAGCGTTACTGAAATACCTCGGCGGAATGCAGGGCGTGAAAGCCGCAACTTTAGA
AGAAATTCAATCCGTACCTGGTATTTCAAAGCAACTTGCCGAAGTGATTTTTGATACGTTACAGCATAGCTAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(202-235)

GIY-YIG catalytic domain (GIY-YIG)

(15-90)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(384-541)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

37.11

99.836

0.37
  uvrC Streptococcus pneumoniae R6

36.782

99.836

0.367
  uvrC Streptococcus pneumoniae D39

36.782

99.836

0.367