Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Machinery gene
Locus tag   ACIO03_RS04240 Genome accession   NZ_CP173231
Coordinates   960638..961405 (-) Length   255 a.a.
NCBI ID   WP_035688099.1    Uniprot ID   A0A0F5EV19
Organism   Avibacterium paragallinarum strain npAP/OH-USA/20230213/S1-4     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 955638..966405
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACIO03_RS04210 (ACIO03_04210) aroB 956026..957114 (-) 1089 WP_264255775.1 3-dehydroquinate synthase -
  ACIO03_RS04215 (ACIO03_04215) aroK 957131..957691 (-) 561 WP_319019334.1 shikimate kinase AroK -
  ACIO03_RS04220 (ACIO03_04220) comE 957892..959214 (-) 1323 WP_264255778.1 type IV pilus secretin PilQ Machinery gene
  ACIO03_RS04225 (ACIO03_04225) - 959223..959582 (-) 360 WP_017806828.1 hypothetical protein -
  ACIO03_RS04230 (ACIO03_04230) - 959582..960130 (-) 549 WP_264255779.1 hypothetical protein -
  ACIO03_RS04235 (ACIO03_04235) - 960096..960608 (-) 513 WP_264255780.1 PilN domain-containing protein -
  ACIO03_RS04240 (ACIO03_04240) comA 960638..961405 (-) 768 WP_035688099.1 hypothetical protein Machinery gene
  ACIO03_RS04245 (ACIO03_04245) - 961564..964113 (+) 2550 WP_264255781.1 penicillin-binding protein 1A -
  ACIO03_RS04250 (ACIO03_04250) - 964210..965166 (-) 957 WP_410681526.1 alpha-2,3-sialyltransferase -

Sequence

Protein


Download         Length: 255 a.a.        Molecular weight: 30475.31 Da        Isoelectric Point: 7.8120

>NTDB_id=957546 ACIO03_RS04240 WP_035688099.1 960638..961405(-) (comA) [Avibacterium paragallinarum strain npAP/OH-USA/20230213/S1-4]
MLKRKISCKKQLQIGIWKGIRTCDFVWFDEENRPRFCVIENDISFERLKPNLLVGECNYSLKTLKFVASITSQYTWIKTL
LLPHSLTISEYEQQCRFLLSQELPIIIDDIWFDYQVEQLKEGVKLTVYAVKKKIAEDYLKIYQPLSIQVLDCISNTVIRA
FHYFIDYKIEKKSLFFYQDEVYVFIINPNTNQIQTIHKTKISLTTLYEKFCQRYSFDCDQVYYYSSLNNTQEYSPDWIRI
NTDIPFIALGNALWK

Nucleotide


Download         Length: 768 bp        

>NTDB_id=957546 ACIO03_RS04240 WP_035688099.1 960638..961405(-) (comA) [Avibacterium paragallinarum strain npAP/OH-USA/20230213/S1-4]
ATGTTAAAAAGAAAAATTTCTTGTAAGAAACAGCTGCAAATTGGTATCTGGAAAGGTATCAGAACTTGTGATTTTGTCTG
GTTTGATGAGGAAAATCGTCCTCGCTTTTGTGTAATTGAGAATGATATTTCGTTTGAGCGTTTGAAACCTAATTTGTTAG
TTGGTGAATGTAATTATTCATTAAAAACTTTGAAATTTGTGGCATCTATTACATCGCAATATACTTGGATAAAAACATTG
TTGCTTCCTCATTCTCTAACTATTTCTGAATATGAACAGCAATGCCGTTTCTTATTGTCTCAAGAATTACCTATTATTAT
CGATGATATTTGGTTTGATTATCAAGTAGAACAGCTAAAAGAAGGCGTTAAATTAACTGTGTATGCGGTTAAAAAAAAGA
TAGCCGAAGATTATCTTAAGATATATCAGCCTTTATCTATTCAAGTTTTAGATTGTATCTCAAATACTGTAATTAGAGCG
TTTCATTATTTTATTGATTATAAAATAGAGAAAAAATCACTGTTTTTTTATCAAGATGAAGTCTATGTGTTTATTATTAA
TCCTAATACAAATCAAATCCAAACTATACATAAAACAAAGATTTCACTTACCACTTTGTATGAGAAATTTTGTCAACGTT
ATTCATTTGATTGTGATCAAGTTTATTATTATTCTTCGTTAAATAATACACAAGAATATTCTCCAGATTGGATTAGAATA
AATACAGATATTCCATTTATAGCATTAGGAAATGCATTATGGAAGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0F5EV19

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Haemophilus influenzae 86-028NP

38.306

97.255

0.373
  comA Haemophilus influenzae Rd KW20

38.306

97.255

0.373