Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ACIVIR_RS04850 Genome accession   NZ_CP173225
Coordinates   927190..929034 (+) Length   614 a.a.
NCBI ID   WP_050279201.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 262     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 922190..934034
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACIVIR_RS04830 - 923022..923801 (+) 780 WP_000290025.1 alpha/beta hydrolase family protein -
  ACIVIR_RS04835 murM 923913..925133 (+) 1221 WP_000286557.1 peptidoglycan bridge formation alanyltransferase MurM -
  ACIVIR_RS04840 murN 925138..926370 (+) 1233 WP_001229512.1 peptidoglycan bridge formation alanyltransferase MurN -
  ACIVIR_RS04845 - 926449..927150 (+) 702 WP_001267415.1 M57 family metalloprotease -
  ACIVIR_RS04850 uvrC 927190..929034 (+) 1845 WP_050279201.1 excinuclease ABC subunit UvrC Machinery gene
  ACIVIR_RS04855 - 929024..929857 (+) 834 WP_054387383.1 metallophosphoesterase -
  ACIVIR_RS04860 - 930039..930839 (-) 801 WP_000714645.1 amino acid ABC transporter substrate-binding protein -
  ACIVIR_RS04865 - 931010..931615 (+) 606 WP_000670181.1 nitroreductase family protein -
  ACIVIR_RS04870 pepV 931628..933028 (+) 1401 WP_000125058.1 dipeptidase PepV -
  ACIVIR_RS04875 - 933082..933660 (+) 579 WP_000078149.1 uracil-DNA glycosylase family protein -

Sequence

Protein


Download         Length: 614 a.a.        Molecular weight: 70406.00 Da        Isoelectric Point: 9.3897

>NTDB_id=957244 ACIVIR_RS04850 WP_050279201.1 927190..929034(+) (uvrC) [Streptococcus pneumoniae strain 262]
MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSYFRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEIN
LIKENKPKYNIMLKDDKSYPFIKITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
YYHIGQCMAHTICKKDETYFKSMAQEVSDFLKGQDNKIIDELKGKMAAAAQTMEFERAAEYRDLIQAIGTLRTKQRVMAK
DLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNLFSYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDQEAVQAL
VDTKILKPQRGEKKQLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGTSPVSAMVV
FVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALPPPDLIVIDGGQGQVNIAKQVIQEELGLDIPIAGLQ
KNDKHQTHELLFGDPLEVVDLSRNSQEFFLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMKHFKSL
TKIKEASVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNKP

Nucleotide


Download         Length: 1845 bp        

>NTDB_id=957244 ACIVIR_RS04850 WP_050279201.1 927190..929034(+) (uvrC) [Streptococcus pneumoniae strain 262]
ATGAACAACTTGATTAAATCAAAACTAGAGCTCTTGCCGACCAGCCCTGGTTGCTACATTCATAAGGATAAAAATGGCAC
CATTATCTATGTAGGAAAGGCTAAAAATCTGCGTAATCGAGTACGGTCCTATTTTCGTGGAAGTCATGATACCAAGACAG
AGGCTCTGGTGTCTGAAATTGTGGATTTTGAATTTATTGTTACGGAGTCTAATATTGAGGCACTTCTCCTAGAAATCAAC
CTGATCAAGGAAAACAAGCCCAAGTACAATATCATGCTCAAGGATGACAAGTCCTATCCTTTCATCAAAATCACCAATGA
GCGCTATCCACGCTTGATTATCACTCGTCAGGTCAAAAAGGACGGAGGTCTTTATTTTGGACCCTATCCCGATGTGGGGG
CAGCCAATGAAATCAAGCGGTTGCTGGATCGGATATTCCCTTTTCGTAAGTGTACCAACCCGCCCTCTAAGGTCTGTTTT
TATTACCATATCGGTCAATGCATGGCCCACACCATCTGTAAGAAGGATGAGACTTATTTCAAGTCTATGGCCCAGGAGGT
TTCTGATTTTCTGAAAGGGCAGGATAACAAAATCATTGATGAGCTAAAGGGCAAAATGGCAGCGGCAGCCCAGACTATGG
AGTTTGAACGTGCGGCGGAATACCGTGACCTGATTCAGGCTATTGGAACGCTTCGAACCAAGCAACGGGTCATGGCGAAA
GATTTGCAAAATCGCGATGTCTTTGGCTACTATGTGGATAAGGGCTGGATGTGTGTGCAGGTTTTCTTTGTCCGTCAGGG
TAAGCTTATCGAGCGCGATGTCAATCTCTTCTCCTACTTCAATGATCCAGATGAGGATTTTTTGACCTATGTAGGACAAT
TCTATCAAGAAAAATCTCACCTAGTTCCCAATGAGGTACTGATTCCGCAGGATATTGATCAAGAAGCCGTTCAGGCCTTG
GTGGATACTAAGATTCTCAAACCCCAGCGTGGAGAGAAAAAACAGCTGGTCAATCTAGCCATCAAAAATGCCCGTGTTAG
CCTAGAGCAGAAGTTCAACCTGCTAGAGAAATCTGTCGAGAAGACCCAAGGAGCTATTGAAAATCTAGGACGCTTGCTTC
AAATCCCAACCCCAGTTCGCATCGAGTCCTTCGATAACTCCAACATCATGGGAACTAGTCCTGTTTCAGCCATGGTGGTC
TTTGTCAACGGCAAGCCTAGTAAGAAGGATTACCGTAAGTATAAAATCAAGACCGTAGTCGGGCCAGACGACTATGCCAG
TATGCGAGAGGTCATTCGCAGACGCTATGGTCGAGTACAGCGTGAGGCTTTGCCTCCTCCAGATTTGATTGTGATTGATG
GGGGGCAAGGTCAAGTCAATATTGCTAAGCAAGTCATCCAAGAAGAACTGGGCTTGGATATTCCAATTGCAGGTCTGCAA
AAGAATGACAAGCACCAAACCCATGAATTGCTCTTTGGAGATCCGCTGGAAGTGGTGGACTTGTCTCGCAATTCTCAGGA
ATTTTTCCTCCTCCAACGCATCCAAGATGAGGTGCACCGCTTTGCCATCACCTTCCACCGCCAACTGCGCTCCAAAAATT
CTTTCTCATCTCAATTGGATGGGATTGATGGTCTGGGACCTAAACGCAAGCAAAATCTTATGAAGCATTTCAAGTCTTTG
ACCAAAATCAAGGAAGCCAGTGTGGATGAGATTGTCGAAGTTGGGGTACCTAGAGTCGTTGCAGAGGCTGTGCAAAGAAA
GTTGAACCCGCAGGGAGAAGCCTTGCCTCAAGTAGCAGAAGAAAGAGTAGATTACCAAACGGAAGGAAACCACAATAAAC
CATAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(197-228)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(372-523)

GIY-YIG catalytic domain (GIY-YIG)

(17-90)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

98.046

100

0.98
  uvrC Streptococcus pneumoniae R6

97.557

100

0.976
  uvrC Streptococcus pneumoniae D39

97.557

100

0.976