Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   ACIQTD_RS01980 Genome accession   NZ_CP173185
Coordinates   394482..395924 (-) Length   480 a.a.
NCBI ID   WP_012897229.1    Uniprot ID   -
Organism   Lactococcus lactis subsp. lactis strain MGEL24009     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 389482..400924
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACIQTD_RS01955 nox 389516..390856 (+) 1341 WP_017864127.1 H2O-forming NADH oxidase -
  ACIQTD_RS01960 - 390946..391335 (+) 390 WP_270249955.1 single-stranded DNA-binding protein -
  ACIQTD_RS01965 groES 391455..391739 (+) 285 WP_017864129.1 co-chaperone GroES -
  ACIQTD_RS01970 groL 391827..393455 (+) 1629 WP_003131585.1 chaperonin GroEL -
  ACIQTD_RS01975 vicX 393501..394313 (-) 813 WP_003131583.1 MBL fold metallo-hydrolase Regulator
  ACIQTD_RS01980 vicK 394482..395924 (-) 1443 WP_012897229.1 cell wall metabolism sensor histidine kinase WalK Regulator
  ACIQTD_RS01985 yycF 395917..396618 (-) 702 WP_003131580.1 response regulator YycF -
  ACIQTD_RS01990 tmk 396796..397431 (+) 636 WP_012897230.1 dTMP kinase -
  ACIQTD_RS01995 - 397564..398424 (+) 861 WP_003131573.1 DNA polymerase III subunit delta' -
  ACIQTD_RS02000 yaaT 398476..399258 (+) 783 WP_017864130.1 stage 0 sporulation family protein Regulator
  ACIQTD_RS02005 yabA 399251..399577 (+) 327 WP_011675472.1 DNA replication initiation control protein YabA -
  ACIQTD_RS02010 rsmI 399577..400452 (+) 876 WP_010905318.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
  ACIQTD_RS02015 - 400529..400720 (-) 192 WP_012897234.1 hypothetical protein -

Sequence

Protein


Download         Length: 480 a.a.        Molecular weight: 54649.12 Da        Isoelectric Point: 4.5889

>NTDB_id=956997 ACIQTD_RS01980 WP_012897229.1 394482..395924(-) (vicK) [Lactococcus lactis subsp. lactis strain MGEL24009]
MIKFFNSMIFKGVVAHLLLFVILFMSSFDYNFAHLSTFIGYYLFSLVFVLVFLNQQHRMIVNVSKQMNDIKNGYLNRDKI
PKGTSEINELYDEILKLGEDIVRTQNNLENQRNQLDSILAYMVDGVIATDRRGNIIMANKSALHYLNTDNDLLMQKNIVE
VLKIADQYNFYDLLEKEPEITIETHDAGNESISLHIKFALFRRESGFISGIIAVLHDMTEQDKAERERRLFVSNVSHELR
TPLTSVKAYLEALEDGAIEDKETASSFINVSLTETNRMIRMISDLLTLSRMDQDRIVLNKEMINLIAFLDYQINRLDQIL
ETESNDLISSNFTLVRKYSEQPIWVEIDTDKIAQVIDNIIGNAIKYSPKGGTITISVEKRESDVLISISDQGMGIPKSDL
LKIFDRFYRVDNASRNSKVGGTGLGLSIVHDIVKIHGGTIFASSEGEGKGTTFSFTLPYSLEAADDWDDGTDEFEFEDNE

Nucleotide


Download         Length: 1443 bp        

>NTDB_id=956997 ACIQTD_RS01980 WP_012897229.1 394482..395924(-) (vicK) [Lactococcus lactis subsp. lactis strain MGEL24009]
ATGATTAAATTTTTTAATTCAATGATTTTTAAAGGAGTAGTTGCACACCTACTTCTTTTTGTCATCCTTTTTATGAGCAG
TTTTGATTACAATTTTGCTCATTTAAGTACTTTTATTGGTTATTACTTATTTTCACTCGTCTTTGTTTTAGTCTTTCTCA
ATCAGCAACATCGCATGATTGTGAATGTTTCTAAACAGATGAATGACATAAAAAATGGCTATTTAAATCGCGATAAAATC
CCAAAAGGGACGAGTGAAATCAATGAATTATATGATGAAATTTTAAAACTTGGTGAAGATATTGTTCGCACGCAGAACAA
TCTTGAAAATCAGCGTAATCAATTAGATAGTATTCTCGCATATATGGTTGATGGCGTCATTGCCACCGATCGTCGTGGAA
ATATTATTATGGCCAATAAATCAGCTTTGCATTATTTGAATACAGATAATGATCTCTTGATGCAAAAAAATATTGTTGAA
GTTTTAAAAATTGCTGACCAATATAATTTTTATGATTTATTAGAAAAAGAACCTGAAATAACTATTGAGACACATGATGC
TGGGAATGAATCCATTTCGCTCCACATTAAATTTGCCCTCTTTCGTCGTGAATCTGGTTTCATCTCAGGAATTATTGCCG
TCTTACATGATATGACTGAACAAGACAAGGCCGAACGAGAGCGCCGTCTCTTTGTTTCCAATGTTTCTCATGAACTCCGA
ACTCCGCTCACCTCAGTAAAAGCCTACTTGGAAGCACTAGAAGACGGAGCCATTGAGGATAAAGAAACAGCGTCATCCTT
TATTAATGTTTCACTTACTGAAACTAATCGGATGATTCGAATGATTTCCGACCTTTTGACTTTATCAAGAATGGATCAAG
ACCGAATCGTTCTTAATAAAGAAATGATTAATTTAATTGCCTTCTTAGACTATCAAATTAACCGTTTAGACCAAATTTTA
GAAACCGAATCAAACGATTTAATCTCTTCTAATTTCACTCTAGTCAGAAAATACTCTGAACAGCCCATCTGGGTCGAAAT
TGATACCGATAAAATTGCTCAAGTTATTGACAATATCATCGGAAATGCAATTAAGTATTCACCTAAAGGTGGAACTATTA
CAATTTCCGTTGAAAAACGTGAAAGTGATGTTCTAATCTCCATCAGTGACCAAGGAATGGGAATTCCAAAATCTGATTTA
CTTAAAATTTTTGACCGTTTCTACCGAGTTGATAATGCTTCAAGAAATTCAAAAGTTGGGGGAACAGGTTTAGGCCTCTC
CATTGTCCATGATATTGTTAAAATACATGGCGGAACAATTTTTGCAAGTTCTGAAGGAGAAGGAAAGGGAACGACCTTTA
GTTTTACTCTTCCATATTCTTTAGAAGCTGCAGATGACTGGGATGATGGTACTGATGAGTTTGAATTTGAGGATAATGAA
TAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(348-459)

PAS domain (PAS_9)

(124-220)

His Kinase A (phospho-acceptor) domain (HisKA)

(228-293)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

51.559

86.875

0.448
  micB Streptococcus pneumoniae Cp1015

47.748

92.5

0.442