Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ACIV1F_RS08630 Genome accession   NZ_CP173176
Coordinates   1748419..1750200 (-) Length   593 a.a.
NCBI ID   WP_096377483.1    Uniprot ID   -
Organism   Staphylococcus aureus strain SA0413Rev     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1743419..1755200
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACIV1F_RS08610 (ACIV1F_001720) racE 1743812..1744612 (-) 801 WP_001039659.1 glutamate racemase -
  ACIV1F_RS08615 (ACIV1F_001721) sdhB 1744848..1745663 (-) 816 WP_000139712.1 succinate dehydrogenase iron-sulfur subunit -
  ACIV1F_RS08620 (ACIV1F_001722) sdhA 1745663..1747429 (-) 1767 WP_000818278.1 succinate dehydrogenase flavoprotein subunit -
  ACIV1F_RS08625 (ACIV1F_001723) - 1747481..1748095 (-) 615 WP_000079317.1 succinate dehydrogenase cytochrome b558 subunit -
  ACIV1F_RS08630 (ACIV1F_001724) uvrC 1748419..1750200 (-) 1782 WP_096377483.1 excinuclease ABC subunit UvrC Machinery gene
  ACIV1F_RS08635 (ACIV1F_001725) - 1750366..1750461 (+) 96 WP_001788625.1 hypothetical protein -
  ACIV1F_RS08640 (ACIV1F_001726) trxA 1750524..1750838 (-) 315 WP_001018928.1 thioredoxin -
  ACIV1F_RS08645 (ACIV1F_001727) mutS/mutS2 1751011..1753359 (-) 2349 WP_001249285.1 endonuclease MutS2 Machinery gene
  ACIV1F_RS08650 (ACIV1F_001728) polX 1753369..1755081 (-) 1713 WP_000161942.1 DNA polymerase/3'-5' exonuclease PolX -

Sequence

Protein


Download         Length: 593 a.a.        Molecular weight: 68659.31 Da        Isoelectric Point: 9.7838

>NTDB_id=956951 ACIV1F_RS08630 WP_096377483.1 1748419..1750200(-) (uvrC) [Staphylococcus aureus strain SA0413Rev]
MEDYKQRIKNKLNVVPMEPGCYLMKDRNDQVIYVGKAKKLRNRLRSYFTGAHDAKTTRLVGEIRRFEFIVTSSETESLLL
ELNLIKQYQPRYNILLKDDKSYPFIKITKEKYPRLLVTRTVKQGTGKYFGPYPNAYSAQETKKLLDRIYPYRKCDKMPDK
LCLYYHIGQCLGPCVYDVDLSKYAQMTKEITDFLNGEDKTILKSLEERMLTASESLDFERAKEYRDLIQHIQNLTNKQKI
MSSDKTTRDVFGYSVDKGWMCIQVFFIRQGNMIKRDTTMIPLQQTEEEEFYTFIGQFYSLNQHILPKEVHVPRNLDKEMI
QSVVDTKIVQPARGPKKDMVDLAAHNAKVSLNNKFELISRDESRTIKAIEELGTQMGIQTPIRIEAFDNSNIQGVDPVSA
MVTFVDGKPDKKNYRKYKIKTVKGPDDYKSMREVVRRRYSRVLNEGLPLPDLIIVDGGKGHMNGVIDVLQNELGLDIPVA
GLQKNDKHQTSELLYGASAEIVPLKKNSQAFYLLHRIQDEVHRFAITFHRQTRQKTGLKSILDDIDGIGNKRKTLLLRSF
GSIKKMKEATLEDFKNIGIPENVAKNLHEQLHK

Nucleotide


Download         Length: 1782 bp        

>NTDB_id=956951 ACIV1F_RS08630 WP_096377483.1 1748419..1750200(-) (uvrC) [Staphylococcus aureus strain SA0413Rev]
TTGGAAGACTATAAGCAACGAATTAAAAATAAATTAAATGTCGTACCTATGGAACCAGGATGCTATTTAATGAAAGATCG
TAATGATCAAGTGATATATGTTGGCAAAGCTAAAAAGCTAAGAAATCGATTGCGATCATATTTTACGGGTGCTCATGATG
CTAAAACAACGAGACTGGTTGGTGAAATACGTCGCTTTGAGTTTATTGTCACGTCAAGTGAAACAGAATCACTTTTACTG
GAATTGAATCTGATTAAACAATATCAACCAAGATATAATATATTATTAAAGGATGATAAAAGTTATCCATTTATTAAAAT
TACGAAGGAGAAATATCCTAGACTACTAGTGACGAGAACTGTAAAACAAGGTACTGGCAAATATTTCGGACCGTATCCGA
ATGCATATTCTGCTCAAGAAACTAAAAAGTTATTAGACAGAATATATCCATATCGCAAATGTGATAAGATGCCAGATAAA
TTATGTCTTTATTACCATATTGGACAATGTTTAGGACCATGTGTATATGACGTTGATTTGAGTAAATACGCACAAATGAC
GAAGGAAATTACTGATTTTCTGAATGGGGAAGACAAAACAATTTTAAAAAGTTTAGAAGAGCGAATGTTAACTGCAAGTG
AATCACTTGATTTTGAACGGGCTAAAGAATATAGAGATTTAATTCAACATATTCAAAATCTGACAAACAAACAAAAAATT
ATGTCATCAGATAAAACGACTCGTGATGTCTTTGGTTATAGTGTTGATAAAGGATGGATGTGTATCCAAGTTTTCTTTAT
ACGACAAGGTAATATGATAAAGCGAGATACAACGATGATTCCATTACAGCAAACAGAAGAAGAAGAATTTTATACATTTA
TTGGACAATTTTATAGCTTAAACCAACATATTTTACCTAAGGAAGTTCATGTACCACGTAATTTGGATAAAGAAATGATT
CAATCTGTTGTGGACACTAAAATCGTTCAACCCGCGCGAGGTCCCAAAAAAGATATGGTTGACCTAGCTGCACATAACGC
TAAAGTATCCTTAAATAATAAATTTGAATTAATATCACGTGATGAGTCCAGAACGATTAAAGCTATTGAAGAACTTGGAA
CACAAATGGGAATTCAAACACCAATTAGAATTGAAGCATTCGATAATTCTAATATTCAAGGTGTGGATCCAGTGTCAGCA
ATGGTTACATTTGTCGACGGTAAACCAGATAAGAAAAATTATAGAAAGTATAAAATCAAAACGGTTAAAGGTCCAGATGA
TTACAAATCAATGAGAGAAGTAGTAAGACGACGATATTCTCGCGTTTTAAACGAAGGATTACCATTACCTGATTTAATAA
TAGTAGATGGTGGTAAAGGACATATGAACGGGGTTATTGATGTGCTACAAAACGAATTAGGTCTTGATATCCCTGTTGCA
GGTTTGCAGAAAAATGATAAACACCAAACATCTGAATTATTATATGGCGCTAGTGCAGAAATTGTACCACTGAAGAAAAA
TAGCCAGGCATTTTATTTGTTGCACCGTATCCAAGATGAGGTTCACAGATTCGCAATCACATTTCATAGACAAACACGTC
AAAAGACAGGCTTGAAATCAATACTTGATGATATAGATGGTATCGGTAACAAACGTAAAACATTATTATTGCGTTCATTC
GGTTCAATCAAGAAAATGAAGGAAGCTACACTTGAAGATTTTAAAAATATAGGTATTCCTGAAAACGTCGCAAAGAACCT
ACATGAACAATTGCATAAATAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(200-233)

GIY-YIG catalytic domain (GIY-YIG)

(19-93)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(379-526)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

57.436

98.651

0.567
  uvrC Streptococcus pneumoniae R6

57.436

98.651

0.567
  uvrC Streptococcus pneumoniae D39

57.436

98.651

0.567