Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   AABA14_RS02045 Genome accession   NZ_AP028607
Coordinates   382111..382743 (+) Length   210 a.a.
NCBI ID   WP_078464081.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain Sep2     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 377111..387743
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AABA14_RS02020 (TKY123642_03860) mvaD 377388..378341 (+) 954 WP_000373457.1 diphosphomevalonate decarboxylase -
  AABA14_RS02025 (TKY123642_03870) - 378328..379335 (+) 1008 WP_000562442.1 phosphomevalonate kinase -
  AABA14_RS02030 (TKY123642_03880) fni 379319..380329 (+) 1011 WP_000210623.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  AABA14_RS02035 (TKY123642_03890) liaF 380407..381105 (+) 699 WP_338168441.1 cell wall-active antibiotics response protein LiaF -
  AABA14_RS02040 (TKY123642_03900) - 381102..382097 (+) 996 WP_338168442.1 sensor histidine kinase -
  AABA14_RS02045 (TKY123642_03910) vraR 382111..382743 (+) 633 WP_078464081.1 response regulator transcription factor Regulator
  AABA14_RS02050 - 382963..383796 (+) 834 Protein_401 trypsin-like peptidase domain-containing protein -
  AABA14_RS02055 - 383800..384297 (+) 498 WP_225355139.1 hypothetical protein -
  AABA14_RS02060 (TKY123642_03930) cbpC 384315..385334 (+) 1020 WP_000698044.1 choline-binding protein CbpC -
  AABA14_RS02065 (TKY123642_03940) tig 385652..386935 (+) 1284 WP_338168443.1 trigger factor -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23663.20 Da        Isoelectric Point: 4.8016

>NTDB_id=95689 AABA14_RS02045 WP_078464081.1 382111..382743(+) (vraR) [Streptococcus pneumoniae strain Sep2]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLNAGARGYMLKTSSADELLHAVRKVAAGELAIEQEVSKKVEYHRNHMELHEDLTARERDVLQLIAKGY
ENQRIADELFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGREDF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=95689 AABA14_RS02045 WP_078464081.1 382111..382743(+) (vraR) [Streptococcus pneumoniae strain Sep2]
ATGAAAATTTTACTAGTTGATGACCATGAAATGGTCCGATTGGGATTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGGATTGACGCGACCTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCATGCCTGTCTTAAATGCTGGTGCTAGGGGCTATATGCTTAAGACTTCTAGTGC
AGATGAATTGCTCCATGCTGTCCGCAAGGTAGCTGCTGGGGAGTTAGCCATTGAGCAAGAGGTCAGCAAGAAGGTCGAAT
ACCACCGAAATCACATGGAACTTCATGAGGACCTAACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAT
GAAAATCAGCGCATCGCTGATGAACTTTTTATCTCTCTTAAGACGGTCAAGACCCATGTGTCCAATATCCTTGCTAAGCT
TGAGGTCAGTGATCGCACTCAGGCAGCAGTCTATGCCTTTCAGCACCACTTGGTGGGGCGGGAAGATTTTTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-115)

Bacterial regulatory proteins, luxR family (GerE)

(145-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41

Multiple sequence alignment