Detailed information NTG0095628

Bioinformatically predicted

Overview

• Name: covS
• Type: Regulator
• Locus tag: LGMS210922A_RS02115
• Genome accession: NZ_AP026069
• Coordinates: 435490..436980 (+)
• Length: 496 a.a.
• NCBI ID: WP_265150285.1
• Uniprot ID: -
• Organism: Lactococcus garvieae strain MS210922A
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 430490..441980

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LGMS210922A_RS02090 (LGMS210922A_04050)	pfkB	430637..431563 (+)	927	WP_265150277.1	1-phosphofructokinase	-
LGMS210922A_RS02095 (LGMS210922A_04060)	-	431578..433482 (+)	1905	WP_014024348.1	PTS fructose transporter subunit IIABC	-
LGMS210922A_RS02100 (LGMS210922A_04070)	-	433594..433836 (+)	243	WP_003135050.1	type B 50S ribosomal protein L31	-
LGMS210922A_RS02105 (LGMS210922A_04080)	-	434053..434604 (+)	552	WP_265150282.1	YceD family protein	-
LGMS210922A_RS02110 (LGMS210922A_04090)	covR	434706..435401 (+)	696	WP_004259096.1	response regulator transcription factor	Regulator
LGMS210922A_RS02115 (LGMS210922A_04100)	covS	435490..436980 (+)	1491	WP_265150285.1	HAMP domain-containing histidine kinase	Regulator
LGMS210922A_RS02120 (LGMS210922A_04110)	-	437377..438948 (+)	1572	WP_265150287.1	ABC transporter permease subunit	-
LGMS210922A_RS02125 (LGMS210922A_04120)	-	438949..439686 (+)	738	WP_265150289.1	amino acid ABC transporter ATP-binding protein	-
LGMS210922A_RS02130 (LGMS210922A_04130)	murD	439825..441186 (+)	1362	WP_265150291.1	UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase	-

Sequence

Protein

• Length: 496 a.a.
• Molecular weight: 56768.70 Da
• Isoelectric Point: 5.1990

>NTDB_id=95628 LGMS210922A_RS02115 WP_265150285.1 435490..436980(+) (covS) [Lactococcus garvieae strain MS210922A]
MVKFFDSKKKKTESLPERKRSIMLRWAFANTIFCFITFTIFTVLVYQLTITTFINSEKEDMMKALDNVEQSLSQSESTLS
EENLANYLAYAKDYTASSQGKENELETLGSMIGSRKSFYVFDVGENLIYSTNSHGFPLKKDVGDGTHAVRTFGEYSGYLV
ERPVYSNKTGKLIGYVQAFYDMSYYYSVRTKLLIALIILEIIALFIAQFVGYFMASRYIKPLERLHDAITTRANNLKADF
KPVVIQTGDEIEELATVYNDMMIKLNDYVDQQKRFVSDVSHELRTPLAVLDGHLNLLNRWGKNDPEVLEESLQASIEEVS
TMRTMLEEMLALARLENIDFQDEDLICDPTEVSNFLKKNFLLIHADLSLTVENNLSPGRLAHIYPNHYEQGLKNLIDNAI
KYSPKDRQEVKIHLEEDDKYIITTVEDHGYGISQEDLKHVFERFFRADKARNRDIGGTGLGLSIIQRIVENYDGEVSVTS
VVGEGSKFTLKIPKIK

Nucleotide

• Length: 1491 bp

>NTDB_id=95628 LGMS210922A_RS02115 WP_265150285.1 435490..436980(+) (covS) [Lactococcus garvieae strain MS210922A]
ATGGTAAAATTTTTTGATTCGAAGAAGAAAAAAACAGAAAGTCTTCCCGAGCGTAAGCGAAGCATCATGCTCCGTTGGGC
ATTTGCAAATACGATTTTTTGTTTTATTACCTTCACTATTTTTACAGTATTGGTTTACCAATTGACCATTACAACCTTCA
TCAATTCTGAAAAAGAGGATATGATGAAAGCTCTGGATAATGTTGAGCAAAGTTTGTCCCAATCGGAAAGCACATTGTCG
GAAGAAAATCTGGCGAATTATTTGGCTTATGCCAAAGACTATACAGCCTCCAGTCAGGGAAAAGAAAATGAGCTAGAAAC
ACTTGGAAGTATGATTGGTTCTAGGAAATCCTTTTATGTTTTTGACGTCGGTGAAAATTTGATTTACTCGACCAATTCTC
ACGGCTTCCCTCTAAAAAAAGATGTGGGGGATGGCACTCATGCTGTACGTACATTTGGTGAATATTCTGGTTATTTGGTC
GAACGACCGGTTTATTCTAATAAAACAGGTAAGCTGATTGGCTATGTGCAGGCTTTCTATGATATGAGTTATTATTATAG
CGTGCGAACAAAGTTACTGATTGCCCTGATTATCCTAGAGATTATTGCTCTCTTTATCGCTCAGTTTGTCGGTTATTTTA
TGGCGAGTCGTTACATCAAGCCTCTGGAACGGTTGCACGATGCGATTACTACACGTGCCAATAACTTGAAGGCGGATTTC
AAACCTGTAGTGATTCAAACAGGTGATGAAATTGAAGAACTGGCGACTGTTTATAATGACATGATGATCAAGCTTAACGA
TTATGTTGATCAGCAGAAACGTTTTGTTTCTGATGTCAGTCACGAGTTACGTACGCCACTTGCGGTTTTGGATGGTCATT
TGAATCTCTTGAACCGTTGGGGGAAAAACGATCCTGAGGTGCTTGAGGAGTCTTTACAGGCCAGTATAGAAGAAGTGAGT
ACGATGAGAACAATGTTGGAAGAGATGCTTGCATTGGCCCGTCTTGAAAACATCGATTTTCAAGATGAAGACCTTATCTG
TGATCCAACAGAAGTTTCTAATTTCCTTAAGAAAAACTTCCTACTTATCCATGCTGATTTAAGCTTAACTGTTGAAAATA
ACTTGTCACCGGGAAGATTGGCTCATATCTACCCGAACCATTATGAACAAGGCTTAAAAAATTTGATTGATAATGCTATA
AAATACTCGCCTAAAGATCGCCAAGAAGTGAAAATCCATCTAGAAGAAGATGATAAATACATTATCACTACGGTTGAGGA
TCATGGCTATGGCATTAGTCAGGAAGATTTAAAACATGTCTTTGAGCGTTTCTTCCGTGCTGATAAAGCGCGAAATCGGG
ATATAGGAGGCACTGGGCTTGGACTGTCTATTATCCAACGCATAGTGGAAAACTACGATGGAGAGGTCAGTGTGACTTCT
GTTGTAGGTGAGGGATCGAAATTCACTTTAAAAATTCCTAAGATTAAATAA

Domains

Predicted by InterproScan.

• HAMP domain (HAMP) (214-266)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (388-494)

• His Kinase A (phospho-acceptor) domain (HisKA) (272-337)

• ArlS sensor domain (ArlS_N) (52-190)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
covS	Lactococcus lactis subsp. lactis strain DGCC12653	55.936	100	0.56