Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   AAA996_RS01890 Genome accession   NZ_AP028606
Coordinates   374501..375133 (+) Length   210 a.a.
NCBI ID   WP_000698434.1    Uniprot ID   Q9S1J7
Organism   Streptococcus pneumoniae strain Sep1     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 369501..380133
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAA996_RS01865 (TKY121773_03670) mvaD 369778..370731 (+) 954 WP_000373461.1 diphosphomevalonate decarboxylase -
  AAA996_RS01870 (TKY121773_03680) - 370718..371725 (+) 1008 WP_000562422.1 phosphomevalonate kinase -
  AAA996_RS01875 (TKY121773_03690) fni 371709..372719 (+) 1011 WP_000210619.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  AAA996_RS01880 (TKY121773_03700) liaF 372797..373495 (+) 699 WP_001224637.1 cell wall-active antibiotics response protein LiaF -
  AAA996_RS01885 (TKY121773_03710) - 373492..374487 (+) 996 WP_000743683.1 sensor histidine kinase -
  AAA996_RS01890 (TKY121773_03720) vraR 374501..375133 (+) 633 WP_000698434.1 response regulator transcription factor Regulator
  AAA996_RS01895 - 375209..375903 (+) 695 Protein_370 DNA alkylation repair protein -
  AAA996_RS01900 (TKY121773_03750) - 376053..376292 (+) 240 WP_000754502.1 hypothetical protein -
  AAA996_RS01905 (TKY121773_03760) cbpG 376373..376967 (+) 595 Protein_372 choline-binding protein CbpG -
  AAA996_RS01910 (TKY121773_03770) - 377269..377661 (+) 393 WP_000378119.1 tyrosine-type recombinase/integrase -
  AAA996_RS01915 (TKY121773_03780) tig 377822..379105 (+) 1284 WP_000116466.1 trigger factor -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23553.03 Da        Isoelectric Point: 4.5791

>NTDB_id=95570 AAA996_RS01890 WP_000698434.1 374501..375133(+) (vraR) [Streptococcus pneumoniae strain Sep1]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=95570 AAA996_RS01890 WP_000698434.1 374501..375133(+) (vraR) [Streptococcus pneumoniae strain Sep1]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGTTTGGGTTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGGATTGACGCGACTTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCATGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGATGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAATATTCTTGCCAAACT
TGAAGTCAGCGATCGTACCCAGGCGGCTGTCTATGCCTTTCAGCACCATTTGGTGGGGCAAGAGGAGTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9S1J7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41

Multiple sequence alignment