Detailed information NTG0095544

Bioinformatically predicted

Overview

• Name: comGE/cglE
• Type: Machinery gene
• Locus tag: QMM33_RS09535
• Genome accession: NZ_AP025940
• Coordinates: 1870456..1870758 (-)
• Length: 100 a.a.
• NCBI ID: WP_000413380.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900700204
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1865456..1875758

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QMM33_RS09500 (PC0204_18380)	rnpA	1866142..1866513 (-)	372	WP_000739246.1	ribonuclease P protein component	-
QMM33_RS09505	-	1866530..1866661 (-)	132	WP_000768904.1	hypothetical protein	-
QMM33_RS09510 (PC0204_18390)	-	1866662..1867852 (-)	1191	WP_000167766.1	acetate kinase	-
QMM33_RS09515 (PC0204_18400)	comYH	1867903..1868856 (-)	954	WP_000345119.1	class I SAM-dependent methyltransferase	Machinery gene
QMM33_RS09520 (PC0204_18410)	-	1868917..1869504 (-)	588	WP_000679774.1	class I SAM-dependent methyltransferase	-
QMM33_RS09525 (PC0204_18420)	comGG/cglG	1869641..1870054 (-)	414	WP_000265630.1	competence type IV pilus minor pilin ComGG	Machinery gene
QMM33_RS09530	comGF/cglF	1870032..1870493 (-)	462	WP_000250545.1	competence type IV pilus minor pilin ComGF	Machinery gene
QMM33_RS09535 (PC0204_18440)	comGE/cglE	1870456..1870758 (-)	303	WP_000413380.1	competence type IV pilus minor pilin ComGE	Machinery gene
QMM33_RS09540 (PC0204_18450)	comGD/cglD	1870721..1871125 (-)	405	WP_000588005.1	competence type IV pilus minor pilin ComGD	Machinery gene
QMM33_RS09545 (PC0204_18460)	comGC/cglC	1871118..1871444 (-)	327	WP_000738638.1	comG operon protein ComGC	Machinery gene
QMM33_RS09550 (PC0204_18470)	comGB/cglB	1871446..1872462 (-)	1017	WP_078133850.1	competence type IV pilus assembly protein ComGB	Machinery gene
QMM33_RS09555 (PC0204_18480)	comGA/cglA/cilD	1872410..1873351 (-)	942	WP_000249550.1	competence type IV pilus ATPase ComGA	Machinery gene
QMM33_RS09560 (PC0204_18490)	-	1873427..1873792 (-)	366	WP_000286415.1	DUF1033 family protein	-
QMM33_RS09565 (PC0204_18500)	-	1873943..1875001 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 100 a.a.
• Molecular weight: 11135.11 Da
• Isoelectric Point: 9.7273

>NTDB_id=95544 QMM33_RS09535 WP_000413380.1 1870456..1870758(-) (comGE/cglE) [Streptococcus pneumoniae strain PZ900700204]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVNINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide

• Length: 303 bp

>NTDB_id=95544 QMM33_RS09535 WP_000413380.1 1870456..1870758(-) (comGE/cglE) [Streptococcus pneumoniae strain PZ900700204]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCTTGCAGACAGGTCAAAATCAGGTAAACATAAACGGAGTTGAGATTCAGGTGTTTTCT
AGCGAAAAGGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

• Type II secretory pathway pseudopilin (ComGE) (16-97)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGE/cglE	Streptococcus mitis NCTC 12261	99	100	0.99
comGE/cglE	Streptococcus pneumoniae Rx1	99	100	0.99
comGE/cglE	Streptococcus pneumoniae D39	99	100	0.99
comGE/cglE	Streptococcus pneumoniae R6	99	100	0.99
comGE/cglE	Streptococcus pneumoniae TIGR4	99	100	0.99
comGE/cglE	Streptococcus mitis SK321	98	100	0.98
comYE	Streptococcus mutans UA140	43.333	90	0.39
comYE	Streptococcus mutans UA159	43.333	90	0.39