Detailed information NTG0954475

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: ACF1RT_RS09985
• Genome accession: NZ_CP172847
• Coordinates: 2004046..2006595 (-)
• Length: 849 a.a.
• NCBI ID: WP_226711214.1
• Uniprot ID: -
• Organism: Streptococcus mutans strain DPC6143
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1999046..2011595

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACF1RT_RS09965 (ACF1RT_09965)	-	2000175..2000735 (-)	561	WP_002268198.1	DNA-3-methyladenine glycosylase I	-
ACF1RT_RS09970 (ACF1RT_09970)	ruvA	2000817..2001410 (-)	594	WP_002262395.1	Holliday junction branch migration protein RuvA	Machinery gene
ACF1RT_RS09975 (ACF1RT_09975)	hexB	2001593..2003548 (-)	1956	WP_226711215.1	DNA mismatch repair endonuclease MutL	Machinery gene
ACF1RT_RS09980 (ACF1RT_09980)	-	2003773..2004051 (+)	279	Protein_1914	transposase	-
ACF1RT_RS09985 (ACF1RT_09985)	hexA	2004046..2006595 (-)	2550	WP_226711214.1	DNA mismatch repair protein MutS	Machinery gene
ACF1RT_RS09990 (ACF1RT_09990)	-	2006588..2006935 (-)	348	WP_002264540.1	YlbF family regulator	-
ACF1RT_RS09995 (ACF1RT_09995)	argR	2006932..2007369 (-)	438	WP_002262400.1	arginine repressor	-
ACF1RT_RS10000 (ACF1RT_10000)	-	2007766..2008221 (-)	456	WP_226705521.1	Crp/Fnr family transcriptional regulator	-
ACF1RT_RS10005 (ACF1RT_10005)	-	2008655..2008879 (-)	225	WP_002266969.1	hypothetical protein	-
ACF1RT_RS10010 (ACF1RT_10010)	-	2009184..2009654 (+)	471	Protein_1920	arginine repressor	-
ACF1RT_RS10015 (ACF1RT_10015)	argS	2009755..2011446 (+)	1692	WP_226711212.1	arginine--tRNA ligase	-

Sequence

Protein

• Length: 849 a.a.
• Molecular weight: 95296.64 Da
• Isoelectric Point: 4.9860

>NTDB_id=954475 ACF1RT_RS09985 WP_226711214.1 2004046..2006595(-) (hexA) [Streptococcus mutans strain DPC6143]
MTKEKLSPGMQQYLDIKKDYPDAFLLFRMGDFYELFYDDAIKAAQILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLI
DLGYKVAIAEQMEDPKKAVGVVKREVVQVITPGTVVDSTKPDSANNFLVSLDTDGSQFGLSYMDLSTGEFYATTLADLPA
VRSEVLNLKARELVIGFELSENEEQLFRKQMNLLLSFEKTVYDDVHLLDDQLKAIELAAAGKLLQYVHNTQKRELSHLQK
LVHYEIKDYLQMAYATKSSLDLLENARSGKKHGSLYWLLDETKTAMGTRLLRTWIDRPLVSSSLISKRQDIIQTFLDHFF
ERSDLSDSLKGVYDIERLASRVSFGKANPKDLLQLGQTLSQVPVIKTILESFASSSLESLINQIDTLPELEALIRSAIDS
NAPITITEGGMIREGFDETLDKYRTVMREGTSWIADIETKERQKSGISTLKIDYNKKDGYYFHVTNSNLSLVPDYFFKKA
TLKNSERFGTAELAKIEGEMLEAREESANLEYDIFMRIRSQVESYIERLQNLAKSLATVDVLQSLAVVAENNHYVRPSFN
HQQEISIENGRHAVVEKVMGSQEYIPNTINFDQKTSIQLITGPNMSGKSTYMRQLALTVIMAQLGSFVAADSADLPIFDA
IFTRIGAADDLISGQSTFMVEMMEANHAIKAATPNSLILFDELGRGTATYDGMALAQAIIEYIHNKVGAKTLFATHYHEL
TDLSTRLTSLVNVHVATLEKDGEVTFLHKIADGPADKSYGIHVAKIAGLPKDLLNRADHILVDLEKMSAAVSVNLKNETK
ESQPVEEQLSLFAIDNNYEELIKKLKQLDLTNLTPRESMNALFDLKELL

Nucleotide

• Length: 2550 bp

>NTDB_id=954475 ACF1RT_RS09985 WP_226711214.1 2004046..2006595(-) (hexA) [Streptococcus mutans strain DPC6143]
ATGACTAAGGAAAAACTCTCTCCAGGAATGCAGCAGTATTTGGATATCAAAAAAGACTATCCAGATGCTTTTTTGCTTTT
CCGCATGGGAGATTTTTATGAACTATTTTATGATGATGCTATCAAGGCCGCTCAAATTTTAGAAATTAGCTTAACAAGTC
GTAATAAAAATGCTGACAATCCTATTCCGATGGCTGGTGTCCCTTATCATTCAGCTCAACAGTATATTGATGTTTTGATT
GATTTGGGTTATAAGGTTGCCATTGCTGAGCAGATGGAAGACCCTAAAAAAGCTGTTGGCGTTGTCAAACGTGAAGTGGT
TCAAGTGATTACCCCGGGTACTGTTGTTGATTCAACTAAGCCAGACAGTGCTAATAATTTTTTAGTCTCTCTGGATACTG
ATGGCAGTCAGTTTGGCCTTTCTTACATGGATTTATCTACTGGGGAATTTTATGCGACAACATTAGCAGATTTGCCAGCA
GTGAGAAGCGAAGTCCTCAATCTCAAGGCGCGTGAATTAGTTATTGGTTTTGAACTGAGTGAGAATGAAGAACAGCTTTT
TCGTAAGCAGATGAACCTGCTCTTATCTTTTGAAAAAACTGTCTATGACGATGTACATTTATTGGATGATCAATTAAAAG
CAATAGAACTTGCTGCAGCTGGCAAACTCTTGCAATATGTTCATAACACACAAAAACGTGAGTTGAGTCATTTGCAAAAG
TTGGTGCATTATGAAATCAAAGATTACTTGCAGATGGCTTATGCTACAAAATCTAGCTTGGATCTGTTAGAAAATGCCAG
AAGCGGGAAAAAACATGGCAGTCTCTACTGGCTTTTAGATGAGACAAAAACAGCTATGGGGACACGTCTTTTGCGAACTT
GGATTGATCGTCCTTTGGTCAGTTCAAGCCTTATCAGTAAACGTCAAGATATTATTCAGACTTTTCTAGATCACTTTTTT
GAGCGCAGTGATCTTAGTGACAGCCTAAAAGGTGTTTATGATATTGAACGTTTGGCCAGCCGTGTTTCATTTGGGAAGGC
CAATCCTAAGGATTTATTGCAATTGGGTCAGACCTTAAGTCAAGTTCCTGTCATTAAGACTATTCTTGAAAGTTTTGCCA
GTTCTAGTTTGGAAAGCCTAATTAATCAAATTGATACTCTTCCAGAATTGGAAGCATTGATTCGTTCGGCTATTGACTCT
AATGCACCTATAACTATTACAGAAGGCGGTATGATTCGAGAGGGGTTTGATGAAACTTTAGATAAGTATCGAACGGTAAT
GCGCGAAGGGACGAGTTGGATTGCTGACATTGAGACTAAGGAACGTCAGAAAAGCGGCATCTCAACCTTGAAGATTGATT
ATAACAAAAAAGACGGTTATTATTTCCATGTCACCAACTCTAATTTGTCTTTAGTACCAGATTACTTCTTTAAAAAGGCA
ACGCTTAAAAATTCTGAGCGCTTTGGGACAGCAGAGCTTGCAAAAATTGAAGGTGAAATGTTAGAAGCGCGTGAAGAATC
AGCCAATTTAGAATATGATATTTTCATGCGTATCAGATCACAGGTTGAATCTTATATTGAGCGTCTTCAAAATCTGGCCA
AGAGTCTAGCGACTGTTGATGTTTTACAAAGTTTAGCAGTAGTAGCTGAGAATAATCATTATGTCAGACCTTCTTTTAAT
CATCAGCAGGAAATCAGTATTGAAAATGGTCGCCATGCTGTTGTTGAGAAGGTTATGGGAAGCCAAGAATATATTCCCAA
TACTATCAATTTTGACCAAAAGACTAGTATTCAACTGATTACTGGACCTAATATGAGCGGTAAGTCAACTTACATGCGGC
AATTAGCTCTGACAGTTATTATGGCTCAATTAGGTTCTTTTGTAGCAGCTGATTCAGCTGATTTACCGATTTTTGATGCT
ATTTTTACACGTATTGGTGCTGCAGATGATTTAATTTCAGGGCAGTCTACCTTTATGGTAGAGATGATGGAAGCCAATCA
TGCTATTAAGGCAGCGACACCTAATTCACTCATTTTATTTGATGAATTAGGACGTGGTACAGCAACTTATGATGGTATGG
CTTTAGCACAGGCTATTATTGAGTATATTCATAATAAAGTTGGGGCTAAAACGCTATTTGCTACCCATTATCATGAGTTG
ACAGACTTGTCAACTAGATTGACAAGTCTTGTCAATGTACATGTTGCTACTCTTGAAAAAGATGGAGAGGTCACTTTTCT
TCATAAAATTGCTGATGGACCAGCTGATAAATCTTATGGAATCCATGTTGCTAAAATTGCCGGCTTGCCTAAAGATTTAC
TTAATCGAGCTGATCACATATTAGTTGATTTAGAAAAAATGAGTGCAGCTGTCTCAGTCAATCTTAAAAACGAGACCAAA
GAAAGCCAACCTGTGGAAGAGCAGTTGTCACTTTTTGCTATTGATAATAATTATGAAGAATTAATCAAAAAATTGAAACA
GTTGGACCTTACCAATTTAACACCAAGAGAATCCATGAATGCCTTATTTGATTTGAAGGAACTATTATAA

Domains

Predicted by InterProScan.

• MutS domain II (MutS_II) (126-239)

• MutS domain I (MutS_I) (8-118)

• MutS domain III (MutS_III) (256-546)

• MutS domain V (MutS_V) (599-785)

• MutS family domain IV (MutS_IV) (415-506)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	72.15	100	0.723
mutS	Pseudomonas stutzeri strain ATCC 17587	37.223	100	0.376