Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ACF1RT_RS04405 Genome accession   NZ_CP172847
Coordinates   862566..864353 (+) Length   595 a.a.
NCBI ID   WP_002270646.1    Uniprot ID   -
Organism   Streptococcus mutans strain DPC6143     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 857566..869353
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACF1RT_RS04380 (ACF1RT_04380) - 857740..858381 (+) 642 WP_002263195.1 DUF4352 domain-containing protein -
  ACF1RT_RS04385 (ACF1RT_04385) eno 858777..860075 (+) 1299 WP_002263196.1 surface-displayed alpha-enolase -
  ACF1RT_RS04390 (ACF1RT_04390) - 860139..860435 (+) 297 WP_002264090.1 TetR/AcrR family transcriptional regulator -
  ACF1RT_RS04395 (ACF1RT_04395) - 860649..861344 (+) 696 WP_002264091.1 YjjG family noncanonical pyrimidine nucleotidase -
  ACF1RT_RS04400 (ACF1RT_04400) - 861388..862448 (-) 1061 Protein_826 low temperature requirement protein A -
  ACF1RT_RS04405 (ACF1RT_04405) uvrC 862566..864353 (+) 1788 WP_002270646.1 excinuclease ABC subunit UvrC Machinery gene
  ACF1RT_RS04410 (ACF1RT_04410) - 864499..865101 (+) 603 WP_002263202.1 nitroreductase family protein -
  ACF1RT_RS04415 (ACF1RT_04415) pepV 865116..866528 (+) 1413 WP_002279729.1 dipeptidase PepV -
  ACF1RT_RS04420 (ACF1RT_04420) - 866601..867188 (+) 588 WP_002270649.1 uracil-DNA glycosylase family protein -
  ACF1RT_RS04425 (ACF1RT_04425) - 867316..867618 (-) 303 WP_002265575.1 helix-turn-helix transcriptional regulator -
  ACF1RT_RS04430 (ACF1RT_04430) - 867709..868059 (+) 351 WP_002265574.1 nuclear transport factor 2 family protein -
  ACF1RT_RS04435 (ACF1RT_04435) - 868077..868880 (+) 804 WP_002265573.1 amidohydrolase family protein -

Sequence

Protein


Download         Length: 595 a.a.        Molecular weight: 68893.28 Da        Isoelectric Point: 9.3836

>NTDB_id=954411 ACF1RT_RS04405 WP_002270646.1 862566..864353(+) (uvrC) [Streptococcus mutans strain DPC6143]
MNELIKHKLELLPDSPGCYIHKDKNGTIIYVGKAKNLKNRVRSYFHGSHNTKTELLVSEIEDFEYIVTGSNTEALLLEIN
LIQENKPKYNIRLKDDKSYPFIKITNEPYPRLLITRQVKKDGGLYFGPYPDSGAATEIKRLLDRLFPFKKCTNPANKVCF
YYHLGQCKAHTICQTDQTYWDSLKEDVKNFLNGRDDKIVNELRDKMTKASELMEFERAAEYRDLIEGIGLLRTKQRVMNQ
DMQDRDIFGYYVDKGWMCVQVFFIRQGKLIQRDVNMFPYYNESEEDFLTYVGQFYQDNRHFIPKEIFIPRNIDETLVKAV
VNTKIIKPQRGEKKQLVNLATKNARVSLQQKFDLLEKDIRKTHGAIENIGDLLNIPKPVRIEAFDNSNIQGTSPVAAMVV
FVDGKPSKKDYRKFKIKTVIGPDDYASMREVIYRRYSRVMRDGLTPPDLIIIDGGQGQVNVARDVIENKLGLDIPIAGLQ
KNDKHQTHELLFGDPLEVIPLPRNSEEFFLLQRIQDEVHRFAITFHRQLRGKNTFSSKLDGIAGLGPKRKQLLMKHFKNL
PNIQKASLDDIINCGIPKNVAENIQESLREEREKG

Nucleotide


Download         Length: 1788 bp        

>NTDB_id=954411 ACF1RT_RS04405 WP_002270646.1 862566..864353(+) (uvrC) [Streptococcus mutans strain DPC6143]
ATGAACGAACTGATTAAACATAAGCTGGAATTGCTGCCAGATAGTCCTGGCTGTTATATTCACAAGGATAAAAACGGCAC
CATTATCTATGTCGGTAAGGCCAAGAACTTAAAAAACCGTGTGCGTAGCTATTTTCACGGCAGCCATAATACCAAGACAG
AATTGTTAGTTTCGGAAATTGAGGATTTTGAATACATTGTTACTGGGTCAAATACAGAAGCTTTACTTCTTGAGATTAAT
CTCATTCAGGAAAATAAGCCCAAGTACAATATCAGACTCAAAGATGATAAGTCTTATCCTTTTATTAAAATTACCAATGA
ACCTTATCCGCGTTTATTGATTACCCGTCAGGTGAAAAAGGATGGCGGTCTTTATTTTGGTCCCTACCCTGATTCGGGAG
CTGCTACTGAAATTAAGCGACTTTTAGATCGTCTCTTTCCCTTTAAAAAATGCACCAACCCAGCCAACAAGGTCTGTTTT
TATTATCATCTCGGGCAATGCAAGGCGCATACCATTTGTCAGACCGACCAAACCTATTGGGATAGTCTTAAAGAAGATGT
GAAAAACTTTCTCAATGGCAGGGACGATAAGATTGTCAATGAACTGCGCGATAAAATGACCAAAGCTTCTGAGCTCATGG
AATTTGAACGTGCAGCTGAATACCGAGATCTTATTGAGGGCATTGGTCTGTTGCGAACCAAGCAGCGCGTCATGAATCAG
GATATGCAGGATCGTGATATTTTTGGTTATTATGTTGATAAAGGCTGGATGTGTGTGCAGGTTTTCTTTATTCGTCAGGG
AAAGCTTATTCAGCGCGATGTCAATATGTTTCCTTATTACAATGAGTCTGAGGAAGATTTTCTGACCTATGTAGGACAGT
TCTATCAGGATAACCGTCACTTTATTCCAAAGGAGATTTTTATTCCTAGAAATATTGATGAAACTTTGGTTAAAGCGGTG
GTCAATACTAAGATTATCAAACCGCAGCGCGGCGAGAAGAAGCAGTTAGTCAATCTGGCAACGAAAAATGCTCGTGTTAG
CCTGCAGCAGAAATTTGATCTCTTGGAAAAAGATATTCGAAAAACGCATGGTGCGATTGAAAATATTGGAGATTTACTTA
ATATTCCTAAGCCAGTGCGCATTGAAGCCTTTGATAATTCCAACATTCAAGGAACCAGTCCTGTTGCAGCTATGGTTGTT
TTTGTGGACGGCAAGCCAAGTAAGAAGGATTATCGTAAATTTAAAATCAAAACCGTTATCGGACCTGATGACTATGCCAG
CATGCGTGAGGTTATTTATCGCAGATATAGCCGTGTCATGCGAGATGGACTGACACCACCAGACCTGATTATTATTGATG
GGGGACAAGGTCAGGTTAATGTAGCGCGTGACGTTATCGAAAATAAATTGGGACTCGATATTCCTATCGCTGGTTTGCAA
AAAAATGATAAGCACCAAACCCATGAGCTGCTCTTTGGTGATCCGCTGGAAGTGATTCCTCTGCCTAGAAATTCAGAAGA
GTTCTTTCTCTTGCAGCGCATTCAAGACGAAGTGCATCGCTTTGCCATTACATTTCATAGGCAGCTGCGCGGTAAAAACA
CCTTCTCATCAAAGCTGGACGGTATTGCAGGGCTCGGCCCTAAGCGCAAGCAATTGCTGATGAAACACTTTAAGAATCTT
CCTAATATTCAAAAGGCCAGCCTAGATGATATTATCAACTGCGGCATTCCAAAAAATGTCGCAGAGAACATTCAAGAGAG
CTTGCGAGAGGAAAGAGAAAAAGGTTAA

Domains

Predicted by InterProScan.

GIY-YIG catalytic domain (GIY-YIG)

(17-90)

UvrB/uvrC motif (UVR)

(196-228)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(372-523)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

76.897

99.664

0.766
  uvrC Streptococcus pneumoniae R6

76.56

99.664

0.763
  uvrC Streptococcus pneumoniae D39

76.56

99.664

0.763