Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ACIA68_RS09810 Genome accession   NZ_CP172818
Coordinates   1948899..1949555 (-) Length   218 a.a.
NCBI ID   WP_022645829.1    Uniprot ID   -
Organism   Escherichia coli strain HS-02     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1943899..1954555
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACIA68_RS09780 yecA 1945150..1945815 (-) 666 WP_022645821.1 UPF0149 family protein YecA -
  ACIA68_RS09800 pgsA 1946465..1947013 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ACIA68_RS09805 uvrC 1947070..1948902 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  ACIA68_RS09810 letA 1948899..1949555 (-) 657 WP_022645829.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ACIA68_RS09815 yecU 1949851..1950027 (+) 177 WP_001307856.1 protein YecU -
  ACIA68_RS09820 yecF 1950014..1950238 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  ACIA68_RS09825 sdiA 1950305..1951027 (-) 723 WP_001154255.1 transcriptional regulator SdiA -
  ACIA68_RS09830 tcyN 1951257..1952009 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  ACIA68_RS09835 tcyL 1952006..1952674 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  ACIA68_RS09840 dcyD 1952689..1953675 (-) 987 WP_001128235.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23938.73 Da        Isoelectric Point: 6.9612

>NTDB_id=954231 ACIA68_RS09810 WP_022645829.1 1948899..1949555(-) (letA) [Escherichia coli strain HS-02]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIAYDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=954231 ACIA68_RS09810 WP_022645829.1 1948899..1949555(-) (letA) [Escherichia coli strain HS-02]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACTGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTATGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482