Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ACIA67_RS09560 Genome accession   NZ_CP172816
Coordinates   1937294..1937950 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain BS-01     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1932294..1942950
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACIA67_RS09530 yecA 1933546..1934211 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  ACIA67_RS09550 pgsA 1934860..1935408 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ACIA67_RS09555 uvrC 1935465..1937297 (-) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  ACIA67_RS09560 letA 1937294..1937950 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ACIA67_RS09565 - 1938092..1938208 (+) 117 Protein_1874 transcriptional regulator -
  ACIA67_RS09570 yecU 1938246..1938422 (+) 177 WP_000590344.1 protein YecU -
  ACIA67_RS09575 yecF 1938409..1938633 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  ACIA67_RS09580 sdiA 1938701..1939423 (-) 723 WP_001152713.1 transcriptional regulator SdiA -
  ACIA67_RS09585 tcyN 1939653..1940404 (-) 752 Protein_1878 L-cystine ABC transporter ATP-binding protein TcyN -
  ACIA67_RS09590 tcyL 1940401..1941069 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  ACIA67_RS09595 dcyD 1941084..1942070 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=954070 ACIA67_RS09560 WP_000611335.1 1937294..1937950(-) (letA) [Escherichia coli strain BS-01]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=954070 ACIA67_RS09560 WP_000611335.1 1937294..1937950(-) (letA) [Escherichia coli strain BS-01]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486