Detailed information    

insolico Bioinformatically predicted

Overview

Name   disA   Type   Machinery gene
Locus tag   ACGH52_RS21495 Genome accession   NZ_CP172447
Coordinates   4708704..4709828 (-) Length   374 a.a.
NCBI ID   WP_030184212.1    Uniprot ID   A0ABV1ST49
Organism   Streptomyces sp. BBFR25     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 4703704..4714828
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACGH52_RS21475 (ACGH52_21475) - 4704622..4706307 (+) 1686 WP_399941550.1 sensor histidine kinase -
  ACGH52_RS21480 (ACGH52_21480) - 4706304..4706975 (+) 672 WP_059302187.1 response regulator transcription factor -
  ACGH52_RS21485 (ACGH52_21485) - 4706994..4707647 (-) 654 WP_193777596.1 phosphatase PAP2 family protein -
  ACGH52_RS21490 (ACGH52_21490) - 4707821..4708657 (+) 837 WP_399941553.1 hypothetical protein -
  ACGH52_RS21495 (ACGH52_21495) disA 4708704..4709828 (-) 1125 WP_030184212.1 DNA integrity scanning diadenylate cyclase DisA Machinery gene
  ACGH52_RS21500 (ACGH52_21500) radA/sms 4709910..4711319 (-) 1410 WP_121701960.1 DNA repair protein RadA Machinery gene
  ACGH52_RS21505 (ACGH52_21505) - 4711902..4713704 (+) 1803 WP_399941558.1 hypothetical protein -
  ACGH52_RS21510 (ACGH52_21510) - 4713731..4714555 (-) 825 WP_210978158.1 hypothetical protein -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40094.85 Da        Isoelectric Point: 5.0058

>NTDB_id=953922 ACGH52_RS21495 WP_030184212.1 4708704..4709828(-) (disA) [Streptomyces sp. BBFR25]
MAANDRAAAPGKSGGSAGADGLMRASLSAVAPGTPLRDGLERVLRGNTGGLIVLGSDKTVEQMCTGGFVLDVEFTATRLR
ELCKLDGGIVLSSDLSKILRAGVQLLPDPTIPTEETGTRHRTADRVSKQVGFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVDEALAELDKLSHAELLELSTVARALGYTGSPETLDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=953922 ACGH52_RS21495 WP_030184212.1 4708704..4709828(-) (disA) [Streptomyces sp. BBFR25]
GTGGCAGCCAACGACCGGGCAGCAGCTCCCGGAAAGTCCGGTGGGAGTGCCGGTGCCGATGGCCTGATGCGCGCCTCACT
GAGCGCCGTGGCGCCCGGCACGCCCCTGCGCGACGGCCTGGAGCGGGTCCTGCGGGGCAACACCGGCGGGCTGATCGTGC
TGGGTTCCGACAAGACCGTCGAGCAGATGTGCACGGGCGGTTTCGTGCTGGACGTCGAGTTCACCGCGACCCGGCTGCGC
GAGCTGTGCAAGCTCGACGGCGGCATCGTGCTGTCCTCGGACCTGTCGAAGATCCTGCGGGCGGGGGTGCAGCTGCTTCC
GGATCCCACCATTCCGACGGAGGAGACCGGTACGCGGCACCGGACTGCCGACCGGGTGAGCAAGCAGGTCGGCTTTCCCG
TCGTGTCGGTTTCGCAGTCGATGCGGCTGATCGCCTTGTACGTGGACGGGCAGCGCAGGGTGCTGGAGGATTCGGCCGCG
ATCCTGTCGCGGGCCAATCAGGCGCTGGCGACCCTGGAGCGGTACAAGCTGCGTCTCGACGAGGTCGCGGGCACGCTGTC
GGCCTTGGAGATCGAGGACCTGGTGACGGTGCGGGACGTCTCGGCGGTCGCGCAGCGACTGGAGATGGTGCGCCGGATCG
CCACCGAGATCGCCGAGTACGTGGTGGAGCTGGGGACGGACGGGCGGCTGCTGGCGCTGCAGCTCGACGAGTTGATCGCC
GGTGTGGAGCCGGAGCGCGAGCTGGTCGTGCGGGACTACGTGCCCGAGCCGACCGCGAAGCGGTCGCGGACGGTCGACGA
GGCGCTCGCCGAGCTGGACAAGCTCAGCCATGCGGAGTTGCTGGAGCTGTCGACGGTGGCACGGGCGCTGGGGTACACCG
GGTCGCCCGAGACGCTGGACTCGGCCGTGTCGCCGCGCGGGTTCCGGCTGCTGGCCAAGGTGCCGCGGCTGCCGGGCGCG
ATCATCGACCGGCTGGTGGAGCACTTCGGCGGACTGCAGAAGCTGCTCGCCGCCAGTGTCGACGACCTCCAGACGGTGGA
CGGCGTCGGCGAGGCGCGGGCGCGCAGTGTCCGGGAGGGGCTGTCACGGCTGGCGGAGTCGTCGATCCTGGAGCGTTACG
TCTGA

Domains

Predicted by InterProScan.

Helix-hairpin-helix motif (HHH_2)

(324-359)

DisA bacterial checkpoint controller nucleotide-binding (DAC)

(38-151)

DisA bacterial checkpoint controller linker region (DisA-linker)

(155-297)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  disA Bacillus subtilis subsp. subtilis str. 168

46.537

96.524

0.449