Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ACHZXT_RS06055 Genome accession   NZ_CP172336
Coordinates   1268862..1269518 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain CE-O153H30     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1263862..1274518
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACHZXT_RS06025 (ACHZXT_06020) yecA 1265114..1265779 (-) 666 WP_000847882.1 UPF0149 family protein YecA -
  ACHZXT_RS06045 (ACHZXT_06040) pgsA 1266428..1266976 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ACHZXT_RS06050 (ACHZXT_06045) uvrC 1267033..1268865 (-) 1833 WP_075862275.1 excinuclease ABC subunit UvrC Machinery gene
  ACHZXT_RS06055 (ACHZXT_06050) letA 1268862..1269518 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ACHZXT_RS06060 (ACHZXT_06055) yecU 1269814..1269990 (+) 177 WP_032160694.1 protein YecU -
  ACHZXT_RS06065 (ACHZXT_06060) yecF 1269977..1270201 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  ACHZXT_RS06070 (ACHZXT_06065) sdiA 1270268..1270990 (-) 723 WP_001461118.1 transcriptional regulator SdiA -
  ACHZXT_RS06075 (ACHZXT_06070) tcyN 1271220..1271972 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  ACHZXT_RS06080 (ACHZXT_06075) tcyL 1271969..1272637 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  ACHZXT_RS06085 (ACHZXT_06080) dcyD 1272652..1273638 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=951935 ACHZXT_RS06055 WP_000611328.1 1268862..1269518(-) (letA) [Escherichia coli strain CE-O153H30]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=951935 ACHZXT_RS06055 WP_000611328.1 1268862..1269518(-) (letA) [Escherichia coli strain CE-O153H30]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGCCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACGGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482