Detailed information NTG0095161

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: AABA08_RS08990
• Genome accession: NZ_AP028602
• Coordinates: 1767299..1768198 (-)
• Length: 299 a.a.
• NCBI ID: WP_000904867.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PF2
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1762299..1773198

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AABA08_RS08970 (TKY092604_17570)	rsmA	1763053..1763925 (-)	873	WP_001216869.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
AABA08_RS08975 (TKY092604_17580)	-	1764056..1764364 (-)	309	WP_000333257.1	hypothetical protein	-
AABA08_RS08980 (TKY092604_17590)	-	1764357..1764998 (-)	642	WP_000565531.1	ABC transporter ATP-binding protein	-
AABA08_RS08985 (TKY092604_17600)	-	1765000..1767030 (-)	2031	WP_000825281.1	bacteriocin-associated integral membrane family protein	-
AABA08_RS08990 (TKY092604_17610)	comR	1767299..1768198 (-)	900	WP_000904867.1	helix-turn-helix domain-containing protein	Regulator
AABA08_RS08995 (TKY092604_17620)	rnmV	1768270..1768830 (-)	561	WP_000664448.1	ribonuclease M5	-
AABA08_RS09000 (TKY092604_17630)	-	1768830..1769603 (-)	774	WP_000575607.1	TatD family hydrolase	-
AABA08_RS09005 (TKY092604_17640)	-	1769909..1770628 (-)	720	Protein_1762	DUF1542 domain-containing protein	-
AABA08_RS09010 (TKY092604_17650)	rpmH	1770837..1770971 (-)	135	WP_000831905.1	50S ribosomal protein L34	-
AABA08_RS09015 (TKY092604_17660)	-	1771116..1772330 (-)	1215	WP_000666469.1	pyridoxal phosphate-dependent aminotransferase	-
AABA08_RS09020 (TKY092604_17670)	-	1772486..1772779 (-)	294	WP_000977365.1	hypothetical protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35191.04 Da
• Isoelectric Point: 5.0703

>NTDB_id=95161 AABA08_RS08990 WP_000904867.1 1767299..1768198(-) (comR) [Streptococcus pneumoniae strain PF2]
MLIGQKIKEIRIEKGISRPDFCGDEQGLTVRQLSRIESGASQPSLPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQI
LREPIYGKEEEYDKKEACLEEIYKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDY
QKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAKLIGDGFLVKKLTEEWQEDVKKYL

Nucleotide

• Length: 900 bp

>NTDB_id=95161 AABA08_RS08990 WP_000904867.1 1767299..1768198(-) (comR) [Streptococcus pneumoniae strain PF2]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGG
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGCCTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTTCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTACGATAAGAAGGAAGCGTGTTTGGAAGAGATTTATAAAACATACTT
TGATAATCTTCCTAAAGAAGAACAATTAGCATGTGAAGTATTGCAGGCGTGTTTGGATACTTCTAGAACTAGAAGGCCTG
AATATGCAGAGTTAATACTTGAGGAACATATGCCTCAGATTATAGAAAAAGAAGCTTATTCAATAAATGATATGTTGTTG
ATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTCTT
TCTTTTGGAACAGAAGAAGGTAACTCAAATAGAGAATTACTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTGTC
TTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCGTGTTTACAAGAAATTATGGATAAAACTCAAGATTAT
CAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGTAGAAAGAGATTTTAGTTTAGCTGAATCATT
TTATCAGTCTTCTAAAACATTTGCGAAGCTAATTGGAGATGGATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGAGG
ATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (7-59)

• ComR tetratricopeptide (ComR_TPR) (70-291)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	37.755	98.328	0.371
comR	Streptococcus suis P1/7	37.801	97.324	0.368
comR	Streptococcus suis 05ZYH33	37.801	97.324	0.368