Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   AABA08_RS01745 Genome accession   NZ_AP028602
Coordinates   339700..340332 (+) Length   210 a.a.
NCBI ID   WP_000698432.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PF2     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 334700..345332
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AABA08_RS01720 (TKY092604_03300) mvaD 334977..335930 (+) 954 WP_000373475.1 diphosphomevalonate decarboxylase -
  AABA08_RS01725 (TKY092604_03310) - 335917..336924 (+) 1008 WP_000562442.1 phosphomevalonate kinase -
  AABA08_RS01730 (TKY092604_03320) fni 336908..337918 (+) 1011 WP_000210623.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  AABA08_RS01735 (TKY092604_03330) liaF 337996..338694 (+) 699 WP_001224634.1 cell wall-active antibiotics response protein LiaF -
  AABA08_RS01740 (TKY092604_03340) - 338691..339686 (+) 996 WP_000743661.1 sensor histidine kinase -
  AABA08_RS01745 (TKY092604_03350) vraR 339700..340332 (+) 633 WP_000698432.1 response regulator transcription factor Regulator
  AABA08_RS01750 (TKY092604_03360) - 340333..340575 (+) 243 WP_001820556.1 DNA alkylation repair protein -
  AABA08_RS01755 (TKY092604_03370) - 340557..340811 (+) 255 WP_000729868.1 DNA alkylation repair protein -
  AABA08_RS01760 - 340888..340983 (+) 96 Protein_344 DNA alkylation repair protein -
  AABA08_RS01765 (TKY092604_03380) - 341442..342044 (+) 603 Protein_345 trypsin-like serine peptidase -
  AABA08_RS01770 (TKY092604_03390) - 342400..342705 (+) 306 WP_000889974.1 tyrosine-type recombinase/integrase -
  AABA08_RS01775 (TKY092604_03400) - 343059..344012 (+) 954 WP_001155321.1 IS30-like element ISSpn8 family transposase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23562.04 Da        Isoelectric Point: 4.6491

>NTDB_id=95089 AABA08_RS01745 WP_000698432.1 339700..340332(+) (vraR) [Streptococcus pneumoniae strain PF2]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGHEEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=95089 AABA08_RS01745 WP_000698432.1 339700..340332(+) (vraR) [Streptococcus pneumoniae strain PF2]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGTTTGGGTTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGGATTGACGCGACCTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCATGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGATGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAACATTCTTGCCAAACT
TGAAGTTAGCGATCGTACCCAGGCGGCTGTCTATGCCTTTCAGCACCATTTGGTCGGGCATGAGGAGTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41

Multiple sequence alignment