Detailed information NTG0950786

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: WHO49_RS19165
• Genome accession: NZ_CP148110
• Coordinates: 3644611..3645768 (-)
• Length: 385 a.a.
• NCBI ID: WP_003227983.1
• Uniprot ID: A0A199WDV9
• Organism: Bacillus subtilis isolate FELIX_MS499
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3639611..3650768

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WHO49_RS19135	yvyF	3639864..3640283 (-)	420	WP_003227995.1	TIGR03826 family flagellar region protein	-
WHO49_RS19140	comFC	3640357..3641079 (-)	723	WP_003227991.1	comF operon protein ComFC	Machinery gene
WHO49_RS19145	comFB	3641043..3641339 (-)	297	WP_003227989.1	late competence protein ComFB	-
WHO49_RS19150	comFA	3641399..3642790 (-)	1392	WP_003243962.1	ATP-dependent helicase ComFA	Machinery gene
WHO49_RS19155	fakBA	3642896..3643741 (-)	846	WP_003244125.1	DegV family protein	-
WHO49_RS19160	degU	3643839..3644528 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
WHO49_RS19165	degS	3644611..3645768 (-)	1158	WP_003227983.1	two-component sensor histidine kinase DegS	Regulator
WHO49_RS19170	yvyE	3645985..3646638 (+)	654	WP_003227979.1	YigZ family protein	-
WHO49_RS19175	tagV	3646638..3647813 (+)	1176	WP_003244117.1	polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagV	-
WHO49_RS19180	tagO	3647886..3648962 (-)	1077	WP_003227975.1	MraY family glycosyltransferase	-
WHO49_RS19185	tuaH	3649107..3650300 (-)	1194	WP_003243252.1	glycosyltransferase family 1 protein	-

Sequence

Protein

• Length: 385 a.a.
• Molecular weight: 44957.76 Da
• Isoelectric Point: 6.2957

>NTDB_id=950786 WHO49_RS19165 WP_003227983.1 3644611..3645768(-) (degS) [Bacillus subtilis isolate FELIX_MS499]
MNKTKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVQTRHARNRLSEVSR
NFHRFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLREVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGAEDGFQEIKNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGETEDQRLAPQFEVALFRLAQEAVSNALKHSESEEITVKVEI
TKDFVILMIKDNGKGFDLKEAKEKKNKSFGLLGMKERVDLLEGTMTIDSKIGLGTFIMIKVPLSL

Nucleotide

• Length: 1158 bp

>NTDB_id=950786 WHO49_RS19165 WP_003227983.1 3644611..3645768(-) (degS) [Bacillus subtilis isolate FELIX_MS499]
ATGAATAAAACAAAGATGGATTCCAAAGTGCTGGATTCTATTTTGATGAAGATGCTGAAAACCGTTGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGGGAGCAGTCACGCCAGCAGTATGAACAGCTGGTCGAAGAACTGAAACAAATTAAACAGCAGG
TGTATGAAGTGATTGAGCTTGGCGATAAACTTGAAGTGCAAACTCGCCATGCGAGAAACCGTTTATCCGAGGTCAGCCGT
AATTTTCATAGATTCAGTGAAGAGGAAATCCGCAATGCTTATGAAAAAGCCCATAAGCTGCAGGTAGAATTGACGATGAT
CCAGCAGCGTGAGAAGCAATTGCGCGAACGGCGGGACGATTTGGAGCGCAGATTGCTAGGGCTTCAGGAAATCATTGAGC
GGTCAGAATCATTAGTAAGCCAAATTACAGTTGTGCTCAACTACTTGAATCAGGATTTGCGCGAAGTTGGACTGCTTCTT
GCTGATGCTCAGGCAAAACAGGATTTCGGCTTAAGAATTATTGAGGCGCAGGAAGAAGAGCGAAAAAGAGTCTCAAGAGA
AATCCATGACGGACCCGCTCAAATGCTGGCGAATGTTATGATGAGATCGGAATTAATCGAGCGGATTTTCCGTGACCGGG
GCGCAGAGGACGGATTCCAAGAAATTAAAAATCTCCGCCAAAATGTTCGGAATGCCCTTTACGAAGTGAGAAGGATTATA
TATGATTTAAGACCGATGGCCCTTGATGACCTAGGCCTGATTCCAACTTTAAGAAAATATCTATATACAACCGAGGAATA
TAACGGGAAGGTCAAAATACATTTTCAGTGCATTGGAGAAACAGAGGATCAGAGGCTAGCGCCTCAGTTTGAGGTTGCGC
TCTTCAGGCTCGCACAGGAAGCTGTGTCTAATGCGCTAAAGCATTCTGAATCTGAAGAAATTACAGTCAAAGTTGAGATC
ACAAAGGATTTTGTGATTTTAATGATAAAAGATAACGGTAAAGGGTTCGACCTGAAGGAAGCGAAAGAGAAGAAAAACAA
ATCATTCGGCTTGCTGGGCATGAAAGAAAGAGTAGATTTATTGGAAGGAACGATGACAATAGATTCGAAAATAGGTCTTG
GGACATTTATTATGATTAAGGTTCCGTTATCTCTTTGA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (180-248)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

3D structure

• AlphaFold DB: A0A199WDV9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	100	100	1