Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ACHP5P_RS09225 Genome accession   NZ_CP172145
Coordinates   1897919..1898575 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain GF66.2     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1892919..1903575
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACHP5P_RS09190 (ACHP5P_09190) dcyD 1893798..1894784 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  ACHP5P_RS09195 (ACHP5P_09195) tcyL 1894799..1895467 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  ACHP5P_RS09200 (ACHP5P_09200) tcyN 1895464..1896216 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  ACHP5P_RS09205 (ACHP5P_09205) sdiA 1896446..1897168 (+) 723 WP_395763314.1 transcriptional regulator SdiA -
  ACHP5P_RS09210 (ACHP5P_09210) yecF 1897236..1897460 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  ACHP5P_RS09215 (ACHP5P_09215) yecU 1897447..1897623 (-) 177 WP_000590344.1 protein YecU -
  ACHP5P_RS09220 (ACHP5P_09220) - 1897661..1897777 (-) 117 WP_001302039.1 hypothetical protein -
  ACHP5P_RS09225 (ACHP5P_09225) letA 1897919..1898575 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ACHP5P_RS09230 (ACHP5P_09230) uvrC 1898572..1900404 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  ACHP5P_RS09235 (ACHP5P_09235) pgsA 1900461..1901009 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ACHP5P_RS09255 (ACHP5P_09255) yecA 1901659..1902324 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=950410 ACHP5P_RS09225 WP_000611335.1 1897919..1898575(+) (letA) [Escherichia coli strain GF66.2]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=950410 ACHP5P_RS09225 WP_000611335.1 1897919..1898575(+) (letA) [Escherichia coli strain GF66.2]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486