Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ACHP5Q_RS01510 Genome accession   NZ_CP172140
Coordinates   294431..295087 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain GF130     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 289431..300087
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACHP5Q_RS01480 (ACHP5Q_01480) dcyD 290310..291296 (+) 987 WP_024705307.1 D-cysteine desulfhydrase -
  ACHP5Q_RS01485 (ACHP5Q_01485) tcyL 291311..291979 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  ACHP5Q_RS01490 (ACHP5Q_01490) tcyN 291976..292728 (+) 753 WP_001273000.1 L-cystine ABC transporter ATP-binding protein TcyN -
  ACHP5Q_RS01495 (ACHP5Q_01495) sdiA 292958..293680 (+) 723 WP_001154255.1 transcriptional regulator SdiA -
  ACHP5Q_RS01500 (ACHP5Q_01500) yecF 293748..293972 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  ACHP5Q_RS01505 (ACHP5Q_01505) yecU 293959..294135 (-) 177 WP_001307856.1 protein YecU -
  ACHP5Q_RS01510 (ACHP5Q_01510) letA 294431..295087 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ACHP5Q_RS01515 (ACHP5Q_01515) uvrC 295084..296916 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  ACHP5Q_RS01520 (ACHP5Q_01520) pgsA 296973..297521 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ACHP5Q_RS01540 (ACHP5Q_01540) yecA 298170..298835 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=950292 ACHP5Q_RS01510 WP_000611328.1 294431..295087(+) (letA) [Escherichia coli strain GF130]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=950292 ACHP5Q_RS01510 WP_000611328.1 294431..295087(+) (letA) [Escherichia coli strain GF130]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482