Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ACHP5R_RS08885 Genome accession   NZ_CP172134
Coordinates   1848273..1848929 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain GF131     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1843273..1853929
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACHP5R_RS08850 (ACHP5R_08850) dcyD 1844153..1845139 (+) 987 WP_001128235.1 D-cysteine desulfhydrase -
  ACHP5R_RS08855 (ACHP5R_08855) tcyL 1845154..1845822 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  ACHP5R_RS08860 (ACHP5R_08860) tcyN 1845819..1846571 (+) 753 WP_001273000.1 L-cystine ABC transporter ATP-binding protein TcyN -
  ACHP5R_RS08865 (ACHP5R_08865) sdiA 1846801..1847523 (+) 723 WP_001154255.1 transcriptional regulator SdiA -
  ACHP5R_RS08870 (ACHP5R_08870) yecF 1847590..1847814 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  ACHP5R_RS08875 (ACHP5R_08875) yecU 1847801..1847977 (-) 177 WP_032160694.1 protein YecU -
  ACHP5R_RS08880 (ACHP5R_08880) - 1848060..1848131 (-) 72 Protein_1730 transcriptional regulator -
  ACHP5R_RS08885 (ACHP5R_08885) letA 1848273..1848929 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ACHP5R_RS08890 (ACHP5R_08890) uvrC 1848926..1850758 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  ACHP5R_RS08895 (ACHP5R_08895) pgsA 1850815..1851363 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ACHP5R_RS08915 (ACHP5R_08915) - 1851948..1852964 (-) 1017 WP_104274773.1 tyrosine-type recombinase/integrase -
  ACHP5R_RS08920 (ACHP5R_08920) - 1852933..1853196 (-) 264 WP_000833838.1 DUF4224 domain-containing protein -
  ACHP5R_RS08925 (ACHP5R_08925) - 1853406..1853588 (-) 183 WP_096839898.1 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=950231 ACHP5R_RS08885 WP_000611328.1 1848273..1848929(+) (letA) [Escherichia coli strain GF131]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=950231 ACHP5R_RS08885 WP_000611328.1 1848273..1848929(+) (letA) [Escherichia coli strain GF131]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACTGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482