Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   AAA982_RS07455 Genome accession   NZ_AP028601
Coordinates   1458820..1459497 (-) Length   225 a.a.
NCBI ID   WP_000548991.1    Uniprot ID   A0A501PEF7
Organism   Streptococcus pneumoniae strain PF1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1453820..1464497
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAA982_RS07430 (TKY113292_14680) - 1453994..1454623 (-) 630 WP_000762097.1 NAD(P)-dependent oxidoreductase -
  AAA982_RS07435 - 1454860..1455223 (+) 364 Protein_1470 hypothetical protein -
  AAA982_RS07440 (TKY113292_14690) - 1455480..1455803 (+) 324 Protein_1471 MazG-like protein -
  AAA982_RS07445 (TKY113292_14700) thrS 1455861..1457804 (+) 1944 WP_338168256.1 threonine--tRNA ligase -
  AAA982_RS07450 (TKY113292_14710) - 1457853..1458827 (-) 975 WP_000887964.1 HAMP domain-containing histidine kinase -
  AAA982_RS07455 (TKY113292_14720) braR 1458820..1459497 (-) 678 WP_000548991.1 response regulator transcription factor Regulator
  AAA982_RS07460 (TKY113292_14730) - 1459653..1460726 (+) 1074 WP_317649087.1 DUF2974 domain-containing protein -
  AAA982_RS07465 (TKY113292_14740) - 1460817..1461119 (-) 303 WP_000281594.1 hypothetical protein -
  AAA982_RS07470 (TKY113292_14750) - 1461188..1461625 (-) 438 WP_001166786.1 Rrf2 family transcriptional regulator -
  AAA982_RS07475 (TKY113292_14760) - 1461701..1462543 (-) 843 WP_000160934.1 metallophosphoesterase family protein -
  AAA982_RS07480 (TKY113292_14770) - 1462655..1463305 (+) 651 WP_000188505.1 metal-dependent transcriptional regulator -
  AAA982_RS07485 (TKY113292_14780) - 1463482..1464014 (+) 533 Protein_1480 nicotinamide mononucleotide transporter -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25936.11 Da        Isoelectric Point: 5.1362

>NTDB_id=95021 AAA982_RS07455 WP_000548991.1 1458820..1459497(-) (braR) [Streptococcus pneumoniae strain PF1]
MHKILLVEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide


Download         Length: 678 bp        

>NTDB_id=95021 AAA982_RS07455 WP_000548991.1 1458820..1459497(-) (braR) [Streptococcus pneumoniae strain PF1]
ATGCACAAGATTTTATTAGTGGAAGATGATCAGGTCATTCGTCAACAGGTCGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTCCTGGTAGAAGACTTTATGGAAGTTTTGAGTCTATTTGTTCAGTCGGAACCTCATCTGGTCCTCATGGATATTG
GTTTGCCCTTGTTTAATGGTTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTACCTATCATGTTTCTTTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGGGCAGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCCAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGATGAGAGTTTGCTGGAATATGCTGGTG
TTATCCTCAATACCAAATCCATGGATTTACATTATCAAGGGCAAGTCTTGAATTTGACCAAGAACGAATTCCAGATTTTA
CGCGTGTTATTTGAGCATGCAGGCAACATCGTAGCACGTGACGATCTGATGCGAGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCTGTCAATGTGGCTCGTTTGCGTAAAAAGTTGGAGGAGCAGGGATTGGTAGGATTTATCGAGA
CCAAGAAAGGAATAGGGTACGGATTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A501PEF7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

49.083

96.889

0.476
  vicR Streptococcus mutans UA159

35.319

100

0.369

Multiple sequence alignment