Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ACHP5S_RS01345 Genome accession   NZ_CP172127
Coordinates   250383..251039 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain GF43     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 245383..256039
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACHP5S_RS01315 (ACHP5S_01315) dcyD 246262..247248 (+) 987 WP_042003790.1 D-cysteine desulfhydrase -
  ACHP5S_RS01320 (ACHP5S_01320) tcyL 247263..247931 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  ACHP5S_RS01325 (ACHP5S_01325) tcyN 247928..248680 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  ACHP5S_RS01330 (ACHP5S_01330) sdiA 248910..249632 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  ACHP5S_RS01335 (ACHP5S_01335) yecF 249700..249924 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  ACHP5S_RS01340 (ACHP5S_01340) yecU 249911..250087 (-) 177 WP_000590347.1 protein YecU -
  ACHP5S_RS01345 (ACHP5S_01345) letA 250383..251039 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ACHP5S_RS01350 (ACHP5S_01350) uvrC 251036..252868 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  ACHP5S_RS01355 (ACHP5S_01355) pgsA 252925..253473 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ACHP5S_RS01375 (ACHP5S_01375) yecA 254123..254788 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=950120 ACHP5S_RS01345 WP_000611328.1 250383..251039(+) (letA) [Escherichia coli strain GF43]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=950120 ACHP5S_RS01345 WP_000611328.1 250383..251039(+) (letA) [Escherichia coli strain GF43]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482