Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ACHOXR_RS09270 Genome accession   NZ_CP172108
Coordinates   1903121..1903777 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain QL57EC     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1898121..1908777
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACHOXR_RS09235 (ACHOXR_09235) dcyD 1899000..1899986 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  ACHOXR_RS09240 (ACHOXR_09240) tcyL 1900001..1900669 (+) 669 WP_272724800.1 cystine ABC transporter permease -
  ACHOXR_RS09245 (ACHOXR_09245) tcyN 1900666..1901418 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  ACHOXR_RS09250 (ACHOXR_09250) sdiA 1901648..1902370 (+) 723 WP_001154260.1 transcriptional regulator SdiA -
  ACHOXR_RS09255 (ACHOXR_09255) yecF 1902438..1902662 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  ACHOXR_RS09260 (ACHOXR_09260) yecU 1902649..1902825 (-) 177 WP_000590344.1 protein YecU -
  ACHOXR_RS09265 (ACHOXR_09265) - 1902863..1902979 (-) 117 WP_001302039.1 hypothetical protein -
  ACHOXR_RS09270 (ACHOXR_09270) letA 1903121..1903777 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ACHOXR_RS09275 (ACHOXR_09275) uvrC 1903774..1905606 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  ACHOXR_RS09280 (ACHOXR_09280) pgsA 1905663..1906211 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ACHOXR_RS09300 (ACHOXR_09300) - 1906907..1907647 (-) 741 WP_088543191.1 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=949989 ACHOXR_RS09270 WP_000611328.1 1903121..1903777(+) (letA) [Escherichia coli strain QL57EC]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=949989 ACHOXR_RS09270 WP_000611328.1 1903121..1903777(+) (letA) [Escherichia coli strain QL57EC]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCTGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482