Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ACHWYH_RS04095 Genome accession   NZ_CP172084
Coordinates   830846..832675 (-) Length   609 a.a.
NCBI ID   WP_112103422.1    Uniprot ID   -
Organism   Haemophilus influenzae strain GA81666     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 825846..837675
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACHWYH_RS04080 - 828023..828778 (+) 756 WP_005652574.1 FCD domain-containing protein -
  ACHWYH_RS04085 uxuA 828798..829982 (+) 1185 WP_112095944.1 mannonate dehydratase -
  ACHWYH_RS04090 - 830035..830748 (-) 714 WP_005693866.1 TerC family protein -
  ACHWYH_RS04095 uvrC 830846..832675 (-) 1830 WP_112103422.1 excinuclease ABC subunit UvrC Machinery gene
  ACHWYH_RS04100 kdsB 832821..833585 (-) 765 WP_112095948.1 3-deoxy-manno-octulosonate cytidylyltransferase -
  ACHWYH_RS04105 lpxK 833656..834654 (-) 999 WP_112103421.1 tetraacyldisaccharide 4'-kinase -
  ACHWYH_RS04110 msbA 834727..836490 (-) 1764 WP_011271803.1 lipid A ABC transporter ATP-binding protein/permease MsbA -

Sequence

Protein


Download         Length: 609 a.a.        Molecular weight: 69641.48 Da        Isoelectric Point: 9.2288

>NTDB_id=949906 ACHWYH_RS04095 WP_112103422.1 830846..832675(-) (uvrC) [Haemophilus influenzae strain GA81666]
MFNYKKFLADVSHEPGVYRMYDDKDQVIYVGKAKDLKKRLSSYFRKNLSSKKTETLVASIHHIDTTLTSSETEALLLEHN
FIKLYQPRYNVLLRDDKSYPFILLTKERHPRITSYRGSKKFAGEYFGPYPHAGAVRETLSLLQKLFPVRQCENSVYSNRS
RPCLQYQIGRCSAPCVQGYVSDEEYNQQVELARLFLQGKDQLVLDYLIGKMEQASRNLDFEQAARYRDQIQAVRSVIEKQ
FVSNERLDDMDIMSIAYQHGLACVQVMFIRQGKVLGNRSYFPKVPANTDLSELTETFVGQFYLQGHQGRSIPNSIIVDRQ
LAEKSELEQLLTEQAGRKVTIQESVKGDKSKYLQLAQVNAKAALNVQLKQSSRMSERYQALCDLLNLPEIKRMECFDISH
TMGNQTVASCVVFNQEGPLKSDYRRFNIEGITGGDDYAAMEQALQKRYERDLEEDKIPDIIFIDGGKGQLNRALNVFQHL
QVKWDKNRPHLIGVAKGVDRRAGQEVLIISKQDREIHLPDDSLALHLIQHIRDESHNHAISGHRKKRQKAFTQSGLETIE
GVGAKRRQALLKYLGGLQGVKKATLDEIASVPGISPKLAERIFETLKND

Nucleotide


Download         Length: 1830 bp        

>NTDB_id=949906 ACHWYH_RS04095 WP_112103422.1 830846..832675(-) (uvrC) [Haemophilus influenzae strain GA81666]
ATGTTCAATTACAAAAAATTCCTCGCTGATGTCTCTCACGAACCTGGTGTTTATCGTATGTATGACGATAAAGATCAGGT
TATTTATGTTGGGAAAGCAAAGGATCTAAAAAAACGTCTTTCAAGCTATTTTCGTAAAAATCTGAGCAGTAAAAAAACAG
AGACGTTGGTTGCGTCAATTCATCATATTGACACCACGCTAACTTCATCTGAAACGGAAGCTTTACTGCTAGAGCATAAT
TTCATCAAGCTTTATCAGCCTCGTTATAACGTGTTATTGCGCGATGATAAATCCTATCCATTTATTTTACTAACCAAAGA
ACGTCATCCAAGAATCACTTCCTATCGTGGTTCTAAAAAATTTGCCGGTGAATATTTCGGGCCTTATCCTCACGCAGGAG
CCGTGCGTGAAACGTTATCGCTTTTGCAAAAACTTTTTCCTGTTCGCCAATGTGAAAATTCCGTTTATTCCAACCGCTCT
CGTCCTTGTTTGCAATATCAAATTGGGCGTTGTTCCGCACCTTGTGTACAGGGATATGTTTCCGATGAAGAATATAATCA
ACAAGTTGAATTAGCCCGTTTATTTTTACAAGGCAAAGATCAACTGGTGTTAGATTATTTAATCGGGAAAATGGAGCAGG
CAAGCAGAAATTTAGATTTTGAACAGGCGGCTCGTTATCGTGATCAGATTCAGGCGGTGCGTTCGGTTATTGAAAAACAA
TTTGTATCCAATGAACGTTTAGATGATATGGATATTATGTCCATCGCTTACCAACACGGTTTGGCTTGTGTACAAGTGAT
GTTTATTCGTCAAGGAAAAGTGCTAGGCAATCGCAGTTATTTCCCAAAAGTCCCTGCCAATACGGATTTATCGGAACTTA
CCGAAACTTTTGTGGGACAATTTTATTTACAAGGTCATCAAGGGCGAAGTATCCCAAATAGTATTATTGTCGATCGTCAA
TTAGCTGAAAAATCAGAGCTTGAGCAACTTCTTACGGAGCAAGCAGGCAGAAAAGTGACGATTCAAGAAAGTGTAAAAGG
CGATAAGAGTAAATACTTACAGCTCGCACAAGTTAATGCTAAAGCGGCTTTAAATGTACAACTTAAACAATCTTCACGAA
TGTCAGAGCGTTATCAAGCGTTGTGTGATCTGTTAAATCTCCCTGAAATTAAGCGTATGGAGTGTTTCGATATAAGCCAC
ACGATGGGAAATCAAACGGTAGCATCTTGTGTTGTCTTTAATCAAGAAGGCCCACTGAAATCTGATTATCGTCGTTTTAA
TATTGAAGGCATTACTGGTGGGGATGATTATGCAGCAATGGAACAAGCGTTGCAGAAACGTTATGAGCGTGATTTAGAAG
AAGATAAAATTCCCGATATTATTTTTATTGATGGTGGAAAAGGGCAATTAAATCGTGCGCTGAACGTGTTCCAACATCTT
CAAGTAAAATGGGATAAAAATAGACCGCACTTAATTGGCGTGGCAAAAGGTGTGGATCGTCGAGCTGGGCAGGAAGTACT
GATCATCAGCAAACAAGACCGCGAAATTCATTTGCCTGATGATAGTTTGGCATTGCATTTGATTCAACACATCCGTGATG
AAAGTCATAATCACGCAATAAGCGGACACCGTAAAAAACGTCAAAAAGCCTTTACACAAAGTGGTTTAGAAACTATTGAA
GGTGTGGGCGCTAAACGTCGTCAGGCTTTACTGAAATATCTTGGCGGTTTACAAGGTGTGAAAAAGGCGACCTTAGATGA
AATAGCCTCTGTACCGGGCATTTCCCCTAAACTTGCTGAAAGGATTTTTGAAACGCTTAAAAACGACTAA

Domains

Predicted by InterProScan.

GIY-YIG catalytic domain (GIY-YIG)

(15-90)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(384-540)

Helix-hairpin-helix domain (HHH_5)

(556-607)

UvrB/uvrC motif (UVR)

(210-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

37.479

97.701

0.366
  uvrC Streptococcus pneumoniae R6

37.143

97.701

0.363
  uvrC Streptococcus pneumoniae D39

37.143

97.701

0.363