Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ACHMKG_RS09745 Genome accession   NZ_CP171874
Coordinates   2026735..2027391 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain YZ22PE67     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2021735..2032391
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACHMKG_RS09710 dcyD 2022614..2023600 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  ACHMKG_RS09715 tcyL 2023615..2024283 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  ACHMKG_RS09720 tcyN 2024280..2025032 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  ACHMKG_RS09725 sdiA 2025262..2025984 (+) 723 WP_001154260.1 transcriptional regulator SdiA -
  ACHMKG_RS09730 yecF 2026052..2026276 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  ACHMKG_RS09735 yecU 2026263..2026439 (-) 177 WP_000590347.1 protein YecU -
  ACHMKG_RS09740 - 2026522..2026593 (-) 72 Protein_1904 transcriptional regulator -
  ACHMKG_RS09745 letA 2026735..2027391 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ACHMKG_RS09750 uvrC 2027388..2029220 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  ACHMKG_RS09755 pgsA 2029277..2029825 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ACHMKG_RS09775 yecA 2030475..2031140 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=949608 ACHMKG_RS09745 WP_000611335.1 2026735..2027391(+) (letA) [Escherichia coli strain YZ22PE67]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=949608 ACHMKG_RS09745 WP_000611335.1 2026735..2027391(+) (letA) [Escherichia coli strain YZ22PE67]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486