Detailed information NTG0949177

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: WFE12_RS19185
• Genome accession: NZ_CP147877
• Coordinates: 3646790..3647947 (-)
• Length: 385 a.a.
• NCBI ID: WP_003227983.1
• Uniprot ID: A0A199WDV9
• Organism: Bacillus subtilis subsp. subtilis str. 168
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3641790..3652947

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WFE12_RS19155	yvyF	3642043..3642462 (-)	420	WP_003227995.1	TIGR03826 family flagellar region protein	-
WFE12_RS19160	comFC	3642536..3643258 (-)	723	WP_003227991.1	comF operon protein ComFC	Machinery gene
WFE12_RS19165	comFB	3643222..3643518 (-)	297	WP_003227989.1	late competence protein ComFB	-
WFE12_RS19170	comFA	3643578..3644969 (-)	1392	WP_003243962.1	ATP-dependent helicase ComFA	Machinery gene
WFE12_RS19175	fakBA	3645075..3645920 (-)	846	WP_003244125.1	DegV family protein	-
WFE12_RS19180	degU	3646018..3646707 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
WFE12_RS19185	degS	3646790..3647947 (-)	1158	WP_003227983.1	two-component sensor histidine kinase DegS	Regulator
WFE12_RS19190	yvyE	3648164..3648817 (+)	654	WP_003227979.1	YigZ family protein	-
WFE12_RS19195	tagV	3648817..3649992 (+)	1176	WP_003244117.1	polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagV	-
WFE12_RS19200	tagO	3650065..3651141 (-)	1077	WP_003227975.1	MraY family glycosyltransferase	-
WFE12_RS19205	tuaH	3651286..3652479 (-)	1194	WP_003243252.1	glycosyltransferase family 1 protein	-

Sequence

Protein

• Length: 385 a.a.
• Molecular weight: 44957.76 Da
• Isoelectric Point: 6.2957

>NTDB_id=949177 WFE12_RS19185 WP_003227983.1 3646790..3647947(-) (degS) [Bacillus subtilis subsp. subtilis str. 168]
MNKTKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVQTRHARNRLSEVSR
NFHRFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLREVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGAEDGFQEIKNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGETEDQRLAPQFEVALFRLAQEAVSNALKHSESEEITVKVEI
TKDFVILMIKDNGKGFDLKEAKEKKNKSFGLLGMKERVDLLEGTMTIDSKIGLGTFIMIKVPLSL

Nucleotide

• Length: 1158 bp

>NTDB_id=949177 WFE12_RS19185 WP_003227983.1 3646790..3647947(-) (degS) [Bacillus subtilis subsp. subtilis str. 168]
ATGAATAAAACAAAGATGGATTCCAAAGTGCTGGATTCTATTTTGATGAAGATGCTGAAAACCGTTGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGGGAGCAGTCACGCCAGCAGTATGAACAGCTGGTCGAAGAACTGAAACAAATTAAACAGCAGG
TGTATGAAGTGATTGAGCTTGGCGATAAACTTGAAGTGCAAACTCGCCATGCGAGAAACCGTTTATCCGAGGTCAGCCGT
AATTTTCATAGATTCAGTGAAGAGGAAATCCGCAATGCTTATGAAAAAGCCCATAAGCTGCAGGTAGAATTGACGATGAT
CCAGCAGCGTGAGAAGCAATTGCGCGAACGGCGGGACGATTTGGAGCGCAGATTGCTAGGGCTTCAGGAAATCATTGAGC
GGTCAGAATCATTAGTAAGCCAAATTACAGTTGTGCTCAACTACTTGAATCAGGATTTGCGCGAAGTTGGACTGCTTCTT
GCTGATGCTCAGGCAAAACAGGATTTCGGCTTAAGAATTATTGAGGCGCAGGAAGAAGAGCGAAAAAGAGTCTCAAGAGA
AATCCATGACGGACCCGCTCAAATGCTGGCGAATGTTATGATGAGATCGGAATTAATCGAGCGGATTTTCCGTGACCGGG
GCGCAGAGGACGGATTCCAAGAAATTAAAAATCTCCGCCAAAATGTTCGGAATGCCCTTTACGAAGTGAGAAGGATTATA
TATGATTTAAGACCGATGGCCCTTGATGACCTAGGCCTGATTCCAACTTTAAGAAAATATCTATATACAACCGAGGAATA
TAACGGGAAGGTCAAAATACATTTTCAGTGCATTGGAGAAACAGAGGATCAGAGGCTAGCGCCTCAGTTTGAGGTTGCGC
TCTTCAGGCTCGCACAGGAAGCTGTGTCTAATGCGCTAAAGCATTCTGAATCTGAAGAAATTACAGTCAAAGTTGAGATC
ACAAAGGATTTTGTGATTTTAATGATAAAAGATAACGGTAAAGGGTTCGACCTGAAGGAAGCGAAAGAGAAGAAAAACAA
ATCATTCGGCTTGCTGGGCATGAAAGAAAGAGTAGATTTATTGGAAGGAACGATGACAATAGATTCGAAAATAGGTCTTG
GGACATTTATTATGATTAAGGTTCCGTTATCTCTTTGA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (180-248)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

3D structure

• AlphaFold DB: A0A199WDV9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	100	100	1