Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   WFE12_RS06375 Genome accession   NZ_CP147877
Coordinates   1230480..1231136 (+) Length   218 a.a.
NCBI ID   WP_003245194.1    Uniprot ID   A0AAE2VF25
Organism   Bacillus subtilis subsp. subtilis str. 168     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1225480..1236136
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WFE12_RS06345 oppF 1225945..1226862 (+) 918 WP_003245567.1 oligopeptide ABC transporter ATP-binding protein OppF -
  WFE12_RS06350 yjbB 1226969..1228186 (+) 1218 WP_010886478.1 MFS transporter -
  WFE12_RS06355 yjbC 1228350..1228928 (+) 579 WP_003244921.1 GNAT family N-acetyltransferase -
  WFE12_RS06360 spx 1229109..1229504 (+) 396 WP_003245483.1 transcriptional regulator Spx -
  WFE12_RS06365 yjbE 1229547..1230203 (-) 657 WP_003232944.1 TerC family protein -
  WFE12_RS06370 - 1230373..1230513 (+) 141 WP_119122854.1 hypothetical protein -
  WFE12_RS06375 mecA 1230480..1231136 (+) 657 WP_003245194.1 adaptor protein MecA Regulator
  WFE12_RS06380 - 1231131..1231253 (-) 123 WP_003245684.1 hypothetical protein -
  WFE12_RS06385 coiA 1231297..1232448 (+) 1152 WP_003245839.1 competence protein CoiA Machinery gene
  WFE12_RS06390 pepF 1232678..1234507 (+) 1830 WP_003245178.1 oligoendopeptidase F -
  WFE12_RS06395 - 1234545..1234712 (-) 168 WP_003244944.1 hypothetical protein -
  WFE12_RS06400 spxH 1235026..1235925 (-) 900 WP_003245184.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25763.69 Da        Isoelectric Point: 4.1174

>NTDB_id=949130 WFE12_RS06375 WP_003245194.1 1230480..1231136(+) (mecA) [Bacillus subtilis subsp. subtilis str. 168]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSKLNVNGSKTTLYSFENR
YYLYVDFCNMTDEEVENQLSILLEYATESSISIHRLEEYGKLIISEHALETIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=949130 WFE12_RS06375 WP_003245194.1 1230480..1231136(+) (mecA) [Bacillus subtilis subsp. subtilis str. 168]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTTTTCTGGGAAGTCATGGATGAAGTTCATGAAGAAGAGGAAT
TCGCTGTGGAAGGCCCACTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGATTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAAATTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTTGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGCTGGAGTACGCAAC
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTAGAAACGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

100

100

1