Detailed information NTG0948142

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: ACG4IV_RS05975
• Genome accession: NZ_CP171688
• Coordinates: 1358327..1359607 (-)
• Length: 426 a.a.
• NCBI ID: WP_000130332.1
• Uniprot ID: A0AAU8WEE3
• Organism: Vibrio cholerae strain M647
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1353327..1364607

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACG4IV_RS05960	ppiD	1353376..1355235 (-)	1860	WP_000969331.1	peptidylprolyl isomerase	-
ACG4IV_RS05965	-	1355388..1355660 (-)	273	WP_001044516.1	HU family DNA-binding protein	-
ACG4IV_RS05970	lon	1355844..1358204 (-)	2361	WP_001047611.1	endopeptidase La	-
ACG4IV_RS05975	clpX	1358327..1359607 (-)	1281	WP_000130332.1	ATP-dependent protease ATP-binding subunit ClpX	Regulator
ACG4IV_RS05980	clpP	1359687..1360313 (-)	627	WP_000121678.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
ACG4IV_RS05985	tig	1360419..1361720 (-)	1302	WP_001198446.1	trigger factor	-
ACG4IV_RS05990	-	1362011..1362229 (-)	219	WP_001881672.1	hypothetical protein	-
ACG4IV_RS05995	-	1362219..1364012 (+)	1794	WP_001139306.1	sensor histidine kinase	-

Sequence

Protein

• Length: 426 a.a.
• Molecular weight: 46490.23 Da
• Isoelectric Point: 4.7780

>NTDB_id=948142 ACG4IV_RS05975 WP_000130332.1 1358327..1359607(-) (clpX) [Vibrio cholerae strain M647]
MTDKSKEGGSSKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKDVLPKKESAALPTPRKIREHLDDYVI
GQEHAKKVLAVAVYNHYKRLRNGDTTSEGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDV
ENIIQKLLQKCDYDVAKAERGIVYIDEIDKISRKSENPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQV
DTSKILFICGGAFAGLDKVIEQRVATGTGIGFGADVRSKDNSKTLSELFTQVEPEDLVKYGLIPEFIGRLPVTATLTELD
EAALIQILCEPKNALTKQYAALFELENVDLEFREDALKAIAAKAMKRKTGARGLRSILEAVLLETMYELPSMEEVSKVVI
DESVINGESAPLLIYSANESQAAGAE

Nucleotide

• Length: 1281 bp

>NTDB_id=948142 ACG4IV_RS05975 WP_000130332.1 1358327..1359607(-) (clpX) [Vibrio cholerae strain M647]
ATGACAGACAAAAGCAAAGAGGGCGGTAGTAGTAAACTGCTGTACTGCTCTTTCTGTGGCAAAAGCCAGCACGAAGTTCG
CAAACTGATCGCAGGTCCGTCCGTGTATATTTGTGATGAGTGCGTTGATTTATGCAACGACATCATCCGCGAAGAGATCA
AAGATGTTCTGCCAAAAAAGGAATCAGCGGCGTTACCGACGCCAAGAAAGATTCGTGAACATCTCGACGATTATGTGATT
GGTCAAGAACACGCCAAAAAAGTGCTAGCCGTTGCGGTATATAACCACTACAAGCGTTTACGTAATGGTGATACGACTAG
CGAAGGCGTTGAGCTGGGCAAGAGTAACATTTTGCTGATTGGCCCAACGGGTAGCGGTAAAACACTACTGGCTGAAACGC
TGGCGCGTTTGCTGGATGTGCCATTTACCATGGCGGATGCGACCACATTAACCGAAGCGGGTTATGTGGGCGAAGATGTA
GAAAATATCATTCAAAAGCTGCTGCAAAAATGCGATTACGATGTTGCAAAAGCGGAGCGTGGTATCGTCTATATCGATGA
AATTGACAAAATTTCTCGTAAGTCTGAAAACCCATCCATCACACGTGACGTGTCGGGTGAAGGGGTTCAGCAAGCGCTGT
TAAAACTGATTGAAGGTACAGTTGCTTCGGTTCCACCACAAGGTGGCCGTAAACATCCTCAGCAGGAATTCCTGCAAGTC
GACACCTCAAAAATCCTATTTATCTGTGGTGGCGCGTTTGCTGGCCTAGATAAAGTGATTGAACAGCGTGTTGCGACAGG
GACTGGTATCGGTTTTGGCGCGGATGTGCGTTCTAAAGACAACAGCAAAACCTTGAGCGAACTGTTTACTCAGGTTGAAC
CTGAAGATTTGGTGAAATACGGTTTGATCCCAGAGTTCATTGGTCGTCTGCCTGTTACGGCAACGCTGACTGAACTGGAT
GAAGCGGCATTGATTCAAATTCTGTGTGAACCAAAGAATGCACTGACCAAACAGTATGCGGCGTTGTTTGAACTGGAAAA
CGTTGATCTGGAGTTTCGTGAAGATGCGCTGAAAGCGATTGCCGCTAAAGCGATGAAGCGTAAAACCGGTGCGCGTGGTC
TACGTTCAATCCTTGAAGCAGTTCTACTGGAAACCATGTATGAACTGCCTTCAATGGAAGAGGTCAGCAAGGTGGTGATT
GACGAATCTGTGATCAACGGAGAGTCCGCACCGCTACTGATTTACAGCGCTAATGAGAGCCAAGCCGCTGGTGCGGAGTA
A

Domains

Predicted by InterProScan.

• ClpX C4-type zinc finger (zf-C4_ClpX) (14-51)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (319-396)

• AAA domain (Cdc48 subfamily) (AAA_2) (114-312)

3D structure

• AlphaFold DB: A0AAU8WEE3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	58.706	94.366	0.554
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	53.333	95.07	0.507