Detailed information NTG0946512

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: ACGS2V_RS05495
• Genome accession: NZ_CP171472
• Coordinates: 1160609..1161883 (+)
• Length: 424 a.a.
• NCBI ID: WP_000130305.1
• Uniprot ID: P0A6H2
• Organism: Escherichia coli strain 1070/13 pAA-
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1155609..1166883

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACGS2V_RS05475 (ACGS2V_05475)	yajG	1156772..1157350 (-)	579	WP_000473497.1	lipoprotein	-
ACGS2V_RS05480 (ACGS2V_05480)	bolA	1157655..1157972 (+)	318	WP_000973448.1	transcriptional regulator BolA	-
ACGS2V_RS05485 (ACGS2V_05485)	tig	1158316..1159614 (+)	1299	WP_001198386.1	trigger factor	-
ACGS2V_RS05490 (ACGS2V_05490)	clpP	1159860..1160483 (+)	624	WP_000122253.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
ACGS2V_RS05495 (ACGS2V_05495)	clpX	1160609..1161883 (+)	1275	WP_000130305.1	ATP-dependent protease ATP-binding subunit ClpX	Regulator
ACGS2V_RS05500 (ACGS2V_05500)	lon	1162071..1164425 (+)	2355	WP_001295325.1	endopeptidase La	-
ACGS2V_RS05505 (ACGS2V_05505)	hupB	1164616..1164906 (+)	291	WP_254892905.1	nucleoid-associated protein HU-beta	-

Sequence

Protein

• Length: 424 a.a.
• Molecular weight: 46356.01 Da
• Isoelectric Point: 4.9982

>NTDB_id=946512 ACGS2V_RS05495 WP_000130305.1 1160609..1161883(+) (clpX) [Escherichia coli strain 1070/13 pAA-]
MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVAPHRERSALPTPHEIRNHLDDYVIG
QEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVEN
IIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDT
SKILFICGGAFAGLDKVISHRVETGSGIGFGATVKAKSDKASEGELLAQVEPEDLIKFGLIPEFIGRLPVVATLNELSEE
ALIQILKEPKNALTKQYQALFNLEGVDLEFRDEALDAIAKKAMARKTGARGLRSIVEAALLDTMYDLPSMEDVEKVVIDE
SVIDGQSKPLLIYGKPEAQQASGE

Nucleotide

• Length: 1275 bp

>NTDB_id=946512 ACGS2V_RS05495 WP_000130305.1 1160609..1161883(+) (clpX) [Escherichia coli strain 1070/13 pAA-]
ATGACAGATAAACGCAAAGATGGCTCAGGCAAATTGCTGTATTGCTCTTTTTGCGGCAAAAGCCAGCATGAAGTGCGCAA
GCTGATTGCCGGTCCATCCGTGTATATCTGCGACGAATGTGTTGATTTATGTAACGACATCATTCGCGAAGAGATTAAAG
AAGTTGCACCGCATCGTGAACGCAGTGCGCTACCGACGCCGCATGAAATTCGCAACCACCTGGACGATTACGTTATCGGC
CAGGAACAGGCGAAAAAAGTGCTGGCGGTCGCGGTATACAACCATTACAAACGTCTGCGCAACGGCGATACCAGCAATGG
TGTCGAGTTGGGCAAAAGTAACATTCTGCTGATCGGTCCGACCGGTTCCGGTAAAACGCTGCTGGCTGAAACGCTGGCGC
GCCTGCTGGACGTCCCGTTCACCATGGCCGACGCAACCACGCTGACCGAAGCCGGTTATGTGGGCGAAGACGTTGAAAAC
ATCATTCAGAAACTGTTGCAGAAATGCGACTACGATGTCCAGAAAGCACAGCGTGGTATTGTCTACATCGATGAAATCGA
CAAGATTTCTCGTAAGTCGGACAACCCGTCTATTACCCGTGACGTTTCCGGTGAAGGCGTACAGCAGGCACTGTTGAAAC
TGATCGAAGGTACTGTTGCTGCCGTTCCACCGCAGGGCGGGCGTAAGCATCCGCAGCAGGAATTTTTGCAGGTTGATACC
TCCAAGATCCTGTTTATTTGTGGCGGTGCGTTTGCCGGTCTGGATAAAGTGATTTCCCACCGTGTAGAAACCGGCTCCGG
CATTGGTTTTGGCGCGACGGTAAAAGCGAAGTCCGACAAAGCAAGCGAAGGCGAGCTGCTGGCGCAGGTTGAACCGGAAG
ATCTGATCAAGTTTGGTCTTATCCCTGAGTTCATTGGTCGTCTGCCGGTTGTCGCAACGTTGAATGAACTGAGCGAAGAA
GCTCTGATTCAGATCCTCAAAGAGCCGAAAAACGCCCTGACCAAGCAGTATCAGGCGCTGTTTAATCTGGAAGGCGTGGA
TCTGGAATTCCGTGACGAGGCGCTGGATGCTATCGCTAAGAAAGCGATGGCGCGTAAAACCGGTGCCCGTGGCCTGCGTT
CCATCGTAGAAGCCGCACTGCTCGATACCATGTACGATCTGCCGTCCATGGAAGACGTCGAAAAAGTGGTTATCGACGAG
TCGGTAATTGATGGTCAAAGCAAACCGTTGCTGATTTATGGTAAGCCGGAAGCGCAACAGGCATCTGGTGAATAA

Domains

Predicted by InterProScan.

• ClpX C4-type zinc finger (zf-C4_ClpX) (13-50)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (317-395)

• AAA domain (Cdc48 subfamily) (AAA_2) (112-310)

3D structure

• AlphaFold DB: P0A6H2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	59.85	94.575	0.566
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	55.392	96.226	0.533