Detailed information NTG0945704

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: ACF0HW_RS10845
• Genome accession: NZ_CP171208
• Coordinates: 2224446..2225468 (-)
• Length: 340 a.a.
• NCBI ID: WP_012117493.1
• Uniprot ID: A7Z4C8
• Organism: Bacillus amyloliquefaciens strain HN11
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 2219446..2230468

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACF0HW_RS10815	-	2219952..2220833 (-)	882	WP_012117498.1	2-dehydropantoate 2-reductase	-
ACF0HW_RS10820	-	2220996..2221478 (+)	483	WP_012117497.1	N-acetyltransferase	-
ACF0HW_RS10825	gerR	2221518..2222093 (-)	576	WP_012117496.1	sporulation-specific transcriptional regulator GerR	-
ACF0HW_RS10830	rpmF	2222252..2222431 (-)	180	WP_003154457.1	50S ribosomal protein L32	-
ACF0HW_RS10835	-	2222453..2222971 (-)	519	WP_012117495.1	DUF177 domain-containing protein	-
ACF0HW_RS10840	-	2223180..2224427 (+)	1248	WP_012117494.1	nucleotidyltransferase	-
ACF0HW_RS10845	sepM	2224446..2225468 (-)	1023	WP_012117493.1	SepM family pheromone-processing serine protease	Regulator
ACF0HW_RS10850	-	2225474..2226253 (-)	780	WP_007409696.1	patatin family protein	-
ACF0HW_RS10855	ylbJ	2226433..2227659 (+)	1227	WP_012117492.1	sporulation integral membrane protein YlbJ	-
ACF0HW_RS10860	coaD	2227678..2228160 (-)	483	WP_007409694.1	pantetheine-phosphate adenylyltransferase	-
ACF0HW_RS10865	rsmD	2228165..2228719 (-)	555	WP_007409693.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
ACF0HW_RS10870	-	2229019..2229291 (-)	273	WP_003154470.1	YlbG family protein	-
ACF0HW_RS10875	ylbF	2229350..2229799 (-)	450	WP_003154472.1	YlbF family regulator	Regulator
ACF0HW_RS10880	-	2229870..2230109 (-)	240	WP_003154475.1	YlbE-like family protein	-

Sequence

Protein

• Length: 340 a.a.
• Molecular weight: 37434.97 Da
• Isoelectric Point: 7.3836

>NTDB_id=945704 ACF0HW_RS10845 WP_012117493.1 2224446..2225468(-) (sepM) [Bacillus amyloliquefaciens strain HN11]
MKAKHFRWVFIILILLIAVTFIKLPYYITQPGEASELRPLIKVDGGYPEKGSLSLMTVKVGPANPYTYLWAKVHPYDEIV
PDESIKEEGESDSDYMKRQLQMMKSSQENAVIAAYQKAGKQVKYSFNGIYASSVVSDMPAKGKIEVGDKIISADGKTYES
AEKLIDYISSKKAGEKVTFHIERDTKEKTVDIVLKSFPDDPKRAGIGVALYTDRNVKVKPDLHFSIENIGGPSAGLMMSL
EIYNQLTKPDETKGYNIAGTGTIDVDGKVGPIGGIDQKVVAADKAGKDIFFAPNQNGAENSDYKNAVKTAKAIKSDMKIV
PVDTMQDALDYLDQLKVKST

Nucleotide

• Length: 1023 bp

>NTDB_id=945704 ACF0HW_RS10845 WP_012117493.1 2224446..2225468(-) (sepM) [Bacillus amyloliquefaciens strain HN11]
ATGAAAGCAAAACATTTTCGCTGGGTGTTTATCATCCTGATCTTATTAATCGCTGTTACATTTATTAAGCTTCCGTATTA
CATCACACAGCCGGGAGAAGCATCAGAGCTGAGACCGCTGATTAAGGTGGACGGAGGCTATCCTGAAAAAGGAAGCCTTT
CCTTGATGACTGTCAAAGTAGGCCCTGCCAATCCGTATACATATCTTTGGGCGAAAGTGCATCCTTATGATGAAATCGTC
CCTGACGAAAGCATAAAAGAAGAGGGCGAATCGGACTCGGATTATATGAAGCGCCAGCTGCAAATGATGAAAAGCTCCCA
AGAAAACGCGGTCATTGCCGCTTATCAAAAAGCCGGGAAACAGGTGAAATACTCATTTAACGGAATTTATGCCAGCTCAG
TCGTCTCTGACATGCCGGCAAAAGGAAAAATAGAGGTCGGTGATAAAATCATCAGCGCGGACGGGAAAACATACGAATCC
GCTGAAAAGCTGATTGATTATATCAGCAGCAAAAAAGCAGGGGAAAAAGTAACGTTTCACATTGAACGGGACACGAAAGA
AAAGACCGTTGACATTGTGCTGAAATCATTCCCGGACGACCCGAAAAGAGCGGGAATCGGTGTCGCATTATATACGGACC
GGAACGTGAAAGTGAAGCCGGATCTTCATTTCAGCATTGAAAACATCGGCGGGCCTTCTGCGGGTCTCATGATGTCTTTA
GAAATTTACAACCAGCTGACAAAACCTGACGAAACAAAAGGCTATAATATAGCCGGAACGGGGACAATCGACGTGGACGG
CAAAGTCGGACCGATCGGCGGAATCGATCAGAAAGTCGTCGCCGCAGACAAAGCGGGAAAAGATATTTTCTTTGCGCCGA
ATCAAAACGGGGCTGAAAATTCTGATTACAAAAATGCGGTAAAAACGGCGAAAGCAATCAAGTCCGATATGAAAATCGTC
CCTGTCGACACCATGCAGGACGCACTTGACTATTTGGATCAGCTGAAAGTAAAAAGCACCTGA

Domains

Predicted by InterProScan.

• PDZ domain (PDZ_2) (127-193)

• Peptidase family M50 (Peptidase_M50) (100-218)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-330)

3D structure

• AlphaFold DB: A7Z4C8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	38.953	100	0.394