Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   ACFIOI_RS05850 Genome accession   NZ_CP170432
Coordinates   1121745..1123007 (+) Length   420 a.a.
NCBI ID   WP_000472302.1    Uniprot ID   P63789
Organism   Staphylococcus aureus strain t1476     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1116745..1128007
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFIOI_RS05815 infC 1117273..1117800 (+) 528 WP_001791162.1 translation initiation factor IF-3 -
  ACFIOI_RS05820 rpmI 1117829..1118029 (+) 201 WP_001125540.1 50S ribosomal protein L35 -
  ACFIOI_RS05825 rplT 1118076..1118432 (+) 357 WP_001138360.1 50S ribosomal protein L20 -
  ACFIOI_RS05830 - 1118574..1119182 (+) 609 WP_000032659.1 NUDIX domain-containing protein -
  ACFIOI_RS05835 - 1119201..1120130 (+) 930 WP_001280018.1 hypothetical protein -
  ACFIOI_RS05840 - 1120135..1120245 (+) 111 WP_001790560.1 hypothetical protein -
  ACFIOI_RS05845 tig 1120293..1121594 (+) 1302 WP_000127573.1 trigger factor -
  ACFIOI_RS05850 clpX 1121745..1123007 (+) 1263 WP_000472302.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  ACFIOI_RS05855 yihA 1123161..1123751 (+) 591 WP_000867697.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  ACFIOI_RS05860 hemA 1123968..1125314 (+) 1347 WP_000545451.1 glutamyl-tRNA reductase -
  ACFIOI_RS05865 ccsA 1125336..1126151 (+) 816 WP_001157329.1 cytochrome c biogenesis protein -
  ACFIOI_RS05870 hemC 1126193..1127119 (+) 927 WP_001230228.1 hydroxymethylbilane synthase -
  ACFIOI_RS05875 - 1127141..1127809 (+) 669 WP_000805950.1 uroporphyrinogen-III synthase -

Sequence

Protein


Download         Length: 420 a.a.        Molecular weight: 46297.48 Da        Isoelectric Point: 4.2645

>NTDB_id=944219 ACFIOI_RS05850 WP_000472302.1 1121745..1123007(+) (clpX) [Staphylococcus aureus strain t1476]
MFKFNEDEENLKCSFCGKDQDQVKKLVAGSGVYICNECIELCSEIVEEELAQNTSEAMTELPTPKEIMDHLNEYVIGQEK
AKKSLAVAVYNHYKRIQQLGPKEDDVELQKSNIALIGPTGSGKTLLAQTLAKTLNVPFAIADATSLTEAGYVGDDVENIL
LRLIQAADFDIDKAEKGIIYVDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPNQEMIQIDTTN
ILFILGGAFDGIEEVIKRRLGEKVIGFSSNEADKYDEQALLAQIRPEDLQAYGLIPEFIGRVPIVANLETLDVTALKNIL
TQPKNALVKQYTKMLELDDVDLEFTEEALSAISEKAIERKTGARGLRSIIEESLIDIMFDVPSNENVTKVVITAQTINEE
TEPELYDAEGNLINNSKTSA

Nucleotide


Download         Length: 1263 bp        

>NTDB_id=944219 ACFIOI_RS05850 WP_000472302.1 1121745..1123007(+) (clpX) [Staphylococcus aureus strain t1476]
ATGTTTAAATTCAATGAAGATGAAGAAAATTTGAAATGCTCTTTTTGCGGAAAAGACCAAGATCAAGTAAAAAAACTTGT
AGCAGGAAGTGGTGTATATATTTGTAATGAGTGTATTGAATTATGCTCAGAAATCGTCGAAGAAGAATTAGCTCAAAACA
CTTCTGAAGCGATGACAGAATTACCTACTCCTAAAGAAATTATGGATCATTTAAACGAATATGTTATTGGTCAAGAAAAA
GCTAAAAAATCTTTAGCTGTAGCTGTTTATAACCACTATAAGCGTATTCAACAATTAGGACCAAAAGAAGATGATGTTGA
ATTACAAAAAAGTAACATTGCATTAATTGGGCCAACAGGTAGTGGTAAAACATTATTAGCTCAAACCTTAGCCAAGACGT
TGAATGTACCATTTGCAATTGCAGATGCGACAAGTTTAACTGAAGCTGGTTATGTAGGCGATGATGTTGAAAATATCTTG
TTGAGATTAATTCAAGCAGCTGACTTTGACATTGATAAAGCCGAAAAAGGTATTATTTATGTAGATGAAATTGATAAAAT
TGCACGTAAATCTGAAAACACATCTATAACACGTGACGTTTCAGGTGAAGGTGTTCAACAAGCATTGCTTAAAATCTTAG
AAGGTACGACTGCAAGTGTTCCGCCACAAGGTGGACGCAAACATCCAAACCAAGAAATGATTCAAATTGATACAACAAAT
ATCTTATTTATTCTTGGTGGTGCCTTTGATGGTATTGAAGAAGTGATTAAGCGCCGTCTTGGTGAAAAAGTTATTGGTTT
CTCAAGCAATGAAGCTGATAAATATGACGAACAAGCATTATTAGCACAAATTCGCCCAGAAGATTTGCAAGCCTATGGTT
TGATTCCTGAATTTATCGGACGTGTGCCAATTGTAGCTAATTTAGAAACATTAGATGTAACTGCGTTGAAAAACATCTTA
ACGCAACCTAAAAATGCACTTGTGAAACAATATACTAAAATGCTGGAATTAGATGATGTGGATTTAGAGTTCACTGAAGA
AGCTTTATCAGCAATTAGTGAAAAAGCAATTGAAAGAAAAACAGGTGCGCGTGGTTTACGTTCAATCATAGAAGAATCGT
TAATCGATATTATGTTTGATGTGCCTTCTAACGAAAATGTAACGAAGGTAGTTATTACAGCACAAACAATTAATGAAGAA
ACTGAACCAGAACTATACGACGCAGAAGGCAATTTAATTAATAATAGTAAAACATCAGCTTAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-305)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P63789

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

66.917

95

0.636
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.456

94.048

0.531