Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   ACFIOM_RS08190 Genome accession   NZ_CP170425
Coordinates   1677208..1677894 (-) Length   228 a.a.
NCBI ID   WP_001792568.1    Uniprot ID   A0A0H2XJ29
Organism   Staphylococcus aureus strain t197     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1672208..1682894
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFIOM_RS08170 rpsT 1673122..1673373 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  ACFIOM_RS08175 holA 1673418..1674392 (-) 975 WP_001282562.1 DNA polymerase III subunit delta -
  ACFIOM_RS08180 comEC 1674449..1676650 (-) 2202 WP_001805151.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  ACFIOM_RS08185 - 1676655..1677116 (-) 462 WP_000439693.1 ComE operon protein 2 -
  ACFIOM_RS08190 comEA 1677208..1677894 (-) 687 WP_001792568.1 ComEA family DNA-binding protein Machinery gene
  ACFIOM_RS08195 - 1677934..1678650 (-) 717 WP_000084829.1 class I SAM-dependent DNA methyltransferase -
  ACFIOM_RS08200 rsfS 1678653..1679006 (-) 354 WP_001088022.1 ribosome silencing factor -
  ACFIOM_RS08205 yqeK 1679007..1679591 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  ACFIOM_RS08210 nadD 1679581..1680150 (-) 570 WP_000725162.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  ACFIOM_RS08215 yhbY 1680153..1680443 (-) 291 WP_000955231.1 ribosome assembly RNA-binding protein YhbY -
  ACFIOM_RS08220 aroE 1680447..1681253 (-) 807 WP_000666761.1 shikimate dehydrogenase -
  ACFIOM_RS08225 yqeH 1681267..1682367 (-) 1101 WP_001280141.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25863.49 Da        Isoelectric Point: 9.3305

>NTDB_id=943987 ACFIOM_RS08190 WP_001792568.1 1677208..1677894(-) (comEA) [Staphylococcus aureus strain t197]
MVLLYQFLLRYKDFLTQWKLYILSAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHEKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=943987 ACFIOM_RS08190 WP_001792568.1 1677208..1677894(-) (comEA) [Staphylococcus aureus strain t197]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTCTAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGAAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTTGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterProScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2XJ29

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

98.238

99.561

0.978
  comEA Staphylococcus aureus N315

97.357

99.561

0.969