Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   V7A38_RS02345 Genome accession   NZ_CP146739
Coordinates   449921..450604 (+) Length   227 a.a.
NCBI ID   WP_004259224.1    Uniprot ID   A0A1I4FNQ8
Organism   Lactococcus garvieae strain L7     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 444921..455604
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V7A38_RS02335 (V7A38_02335) rpoC 445028..448675 (+) 3648 WP_004259228.1 DNA-directed RNA polymerase subunit beta' -
  V7A38_RS02340 (V7A38_02340) - 448767..449675 (-) 909 WP_014024330.1 diacylglycerol kinase family protein -
  V7A38_RS02345 (V7A38_02345) mecA 449921..450604 (+) 684 WP_004259224.1 adaptor protein MecA Regulator
  V7A38_RS02350 (V7A38_02350) - 450608..451864 (+) 1257 WP_014024331.1 glycosyltransferase family 4 protein -
  V7A38_RS02355 (V7A38_02355) sufC 451942..452712 (+) 771 WP_014024332.1 Fe-S cluster assembly ATPase SufC -
  V7A38_RS02360 (V7A38_02360) sufD 452784..454040 (+) 1257 WP_014024333.1 Fe-S cluster assembly protein SufD -
  V7A38_RS02365 (V7A38_02365) - 454040..455251 (+) 1212 WP_014024334.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 227 a.a.        Molecular weight: 26239.38 Da        Isoelectric Point: 4.0202

>NTDB_id=943919 V7A38_RS02345 WP_004259224.1 449921..450604(+) (mecA) [Lactococcus garvieae strain L7]
MQYEEINEKTIKISLTFQDLVDHDVKLSDFFTNQSMVENLFYELVEELGLEERFSSGLLTFQIQPFPKGVNIIVTEENID
IDPNNLPDDPEEFEQLMTDFFGRVEDLKQNGGTMADTSTTETKETKVENKPDPDFVFYSLEFENMSQLLTAVKNVKIDAE
ESELYSYQDKFYLIILDNQKSKGKTAVSSMRARMLEYGQETVNSRETLQEYGEILINTRALEVLSKI

Nucleotide


Download         Length: 684 bp        

>NTDB_id=943919 V7A38_RS02345 WP_004259224.1 449921..450604(+) (mecA) [Lactococcus garvieae strain L7]
ATGCAATACGAAGAAATAAACGAAAAAACGATAAAGATTAGCCTAACCTTTCAAGATTTGGTTGATCATGATGTCAAACT
CTCTGATTTTTTTACTAACCAGTCGATGGTTGAAAATCTTTTTTATGAATTAGTAGAAGAGCTAGGACTTGAGGAAAGAT
TCTCATCAGGACTTTTAACTTTCCAAATTCAACCTTTCCCTAAAGGGGTGAATATCATTGTTACCGAGGAAAATATTGAT
ATTGATCCCAATAATCTCCCGGATGATCCTGAAGAATTTGAGCAGCTGATGACGGATTTCTTTGGGCGTGTGGAAGATTT
AAAACAAAATGGCGGAACAATGGCAGATACAAGTACAACTGAAACGAAAGAAACAAAAGTAGAAAATAAACCAGACCCAG
ATTTTGTCTTCTATTCTCTAGAATTTGAAAATATGTCTCAACTTTTGACAGCAGTAAAAAATGTTAAAATTGATGCAGAA
GAGTCTGAACTTTACAGTTACCAAGATAAGTTTTATTTGATTATTTTGGACAATCAAAAATCAAAAGGAAAAACAGCCGT
AAGTTCGATGCGTGCCCGAATGTTAGAATACGGCCAGGAAACGGTCAACAGTCGTGAAACCCTACAAGAATACGGCGAGA
TACTAATCAATACGCGTGCTTTGGAAGTTCTCTCAAAAATTTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-224)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1I4FNQ8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Lactococcus lactis subsp. cremoris KW2

54.661

100

0.568
  mecA Lactococcus lactis subsp. lactis strain DGCC12653

54.077

100

0.555