Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ACFIOO_RS04940 Genome accession   NZ_CP170406
Coordinates   1040852..1042633 (+) Length   593 a.a.
NCBI ID   WP_054190268.1    Uniprot ID   -
Organism   Staphylococcus aureus strain t21635     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1035852..1047633
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFIOO_RS04920 polX 1035972..1037684 (+) 1713 WP_054190270.1 DNA polymerase/3'-5' exonuclease PolX -
  ACFIOO_RS04925 mutS/mutS2 1037694..1040042 (+) 2349 WP_054190269.1 endonuclease MutS2 Machinery gene
  ACFIOO_RS04930 trxA 1040215..1040529 (+) 315 WP_001018928.1 thioredoxin -
  ACFIOO_RS04935 - 1040592..1040662 (-) 71 Protein_959 hypothetical protein -
  ACFIOO_RS04940 uvrC 1040852..1042633 (+) 1782 WP_054190268.1 excinuclease ABC subunit UvrC Machinery gene
  ACFIOO_RS04945 - 1042958..1043572 (+) 615 WP_000079317.1 succinate dehydrogenase cytochrome b558 subunit -
  ACFIOO_RS04950 sdhA 1043624..1045390 (+) 1767 WP_000818278.1 succinate dehydrogenase flavoprotein subunit -
  ACFIOO_RS04955 sdhB 1045390..1046205 (+) 816 WP_054190267.1 succinate dehydrogenase iron-sulfur subunit -
  ACFIOO_RS04960 racE 1046439..1047239 (+) 801 WP_001039659.1 glutamate racemase -

Sequence

Protein


Download         Length: 593 a.a.        Molecular weight: 68721.42 Da        Isoelectric Point: 9.7837

>NTDB_id=943340 ACFIOO_RS04940 WP_054190268.1 1040852..1042633(+) (uvrC) [Staphylococcus aureus strain t21635]
MEDYKQRIKNKLNVVPMEPGCYLMKDRNDQVIYVGKAKKLRNRLRSYFTGAHDAKTTRLVGEIRRFEFIVTSSETESLLL
ELNLIKQYQPRYNILLKDDKSYPFIKITKEKYPRLLVTRTVKQGTGKYFGPYPNAYSAQETKKLLDRIYPYRKCDKMPDK
LCLYYHIGQCLGPCVYDVDLSRYAQMTKEITDFLNGEDKTILKSLEERMLTASESLDFERAKEYRDLIQHIQNLTNKQKI
MSSDKTIRDVFGYSVDKGWMCIQVFFIRQGNMIKRDTTMIPLQQTEEEEFYTFIGQFYSLNQHILPKEVHVPRNLDKEMI
QSVVDTKIVQPARGPKKDMVDLAEHNAKVSLNNKFELISRDESRTIKAIEELGTQMGIQTPIRIEAFDNSNIQGVDPVSA
MVTFVDGKPDKKNYRKYKIKTVKGPDDYKSMREVVRRRYSRVLNEGLPLPDLIIVDGGKGHMNGVIDVLQNELGLDIPVA
GLQKNDKHQTSELLYGASAEIVPLKKNSQAFYLLHRIQDEVHRFAITFHRQTRQKTGLKSILDDIDGIGSKRKTLLLRSF
GSIKKMKEATLEDFKKIGIPENVAKNLHEQLNK

Nucleotide


Download         Length: 1782 bp        

>NTDB_id=943340 ACFIOO_RS04940 WP_054190268.1 1040852..1042633(+) (uvrC) [Staphylococcus aureus strain t21635]
TTGGAAGACTATAAGCAACGAATTAAAAATAAATTAAATGTCGTACCTATGGAACCAGGCTGCTATTTAATGAAAGATCG
TAATGATCAAGTGATATATGTTGGCAAAGCTAAAAAACTACGAAATCGATTGCGATCATATTTTACGGGCGCTCATGATG
CTAAAACAACGAGACTGGTTGGTGAAATACGTCGCTTTGAGTTTATTGTCACGTCAAGTGAAACAGAGTCACTTTTACTG
GAATTGAATCTGATTAAACAATATCAACCAAGGTACAATATATTATTAAAGGATGATAAAAGTTATCCATTTATTAAAAT
TACGAAGGAAAAATATCCTAGACTACTAGTGACGAGAACTGTAAAACAAGGTACTGGCAAATATTTCGGACCGTATCCGA
ATGCATATTCTGCTCAAGAAACCAAAAAGTTATTAGACAGAATATATCCATATCGCAAATGTGATAAGATGCCAGATAAA
TTATGTCTTTATTATCATATTGGACAATGTTTAGGACCATGTGTATATGACGTTGATTTGAGTAGATATGCACAAATGAC
GAAGGAAATCACTGATTTTCTGAATGGGGAAGACAAAACAATATTAAAAAGTTTAGAAGAGCGAATGTTAACTGCAAGTG
AATCACTGGACTTTGAACGTGCTAAAGAATATAGAGATTTAATTCAACATATTCAAAATCTAACTAACAAACAAAAAATT
ATGTCGTCGGATAAAACGATTCGTGATGTCTTTGGTTATAGTGTTGATAAAGGATGGATGTGTATCCAAGTTTTCTTTAT
ACGACAAGGTAATATGATAAAACGAGATACAACGATGATTCCATTACAGCAAACAGAAGAAGAAGAATTTTATACATTTA
TTGGACAATTTTATAGCTTAAACCAACATATTTTACCTAAAGAAGTTCATGTACCACGTAATTTGGATAAAGAAATGATT
CAATCTGTTGTGGACACTAAAATCGTTCAACCCGCTCGAGGTCCCAAAAAAGATATGGTTGACTTAGCTGAACATAACGC
TAAAGTATCCTTAAACAATAAATTTGAATTAATATCACGTGATGAGTCTAGAACAATTAAAGCTATTGAAGAACTTGGAA
CACAAATGGGAATTCAAACACCAATTAGAATTGAAGCATTCGATAATTCTAATATTCAAGGTGTGGATCCAGTGTCAGCA
ATGGTTACATTTGTCGACGGTAAACCAGACAAGAAAAATTATAGAAAGTATAAAATCAAAACGGTTAAAGGTCCAGATGA
TTACAAATCAATGAGAGAAGTAGTAAGACGCCGATATTCTCGGGTTTTAAACGAAGGATTACCATTACCTGATTTAATAA
TAGTAGATGGTGGTAAAGGACATATGAACGGGGTTATTGATGTGCTACAAAACGAATTAGGTCTTGATATCCCTGTTGCA
GGTTTGCAGAAAAATGATAAACACCAAACATCTGAATTATTATATGGCGCTAGTGCAGAAATTGTACCACTGAAGAAAAA
TAGTCAAGCATTTTATTTGTTGCATCGTATCCAAGATGAGGTTCACAGATTCGCAATCACATTTCATAGACAAACACGTC
AAAAGACAGGCTTGAAATCAATACTTGATGATATAGATGGTATTGGTAGCAAACGTAAAACATTATTATTGCGTTCATTT
GGTTCAATCAAGAAAATGAAGGAAGCTACACTTGAAGATTTTAAAAAAATTGGTATTCCTGAAAACGTCGCAAAGAACCT
ACATGAACAATTGAATAAATAA

Domains

Predicted by InterProScan.

GIY-YIG catalytic domain (GIY-YIG)

(19-93)

UvrB/uvrC motif (UVR)

(200-233)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(379-526)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae R6

57.607

98.651

0.568
  uvrC Streptococcus pneumoniae TIGR4

57.607

98.651

0.568
  uvrC Streptococcus pneumoniae D39

57.607

98.651

0.568