Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   ACFIOQ_RS05720 Genome accession   NZ_CP170404
Coordinates   1100342..1101604 (+) Length   420 a.a.
NCBI ID   WP_000472293.1    Uniprot ID   Q6GG31
Organism   Staphylococcus aureus strain t7960     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1095342..1106604
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFIOQ_RS05685 infC 1095870..1096397 (+) 528 WP_001791162.1 translation initiation factor IF-3 -
  ACFIOQ_RS05690 rpmI 1096426..1096626 (+) 201 WP_001125540.1 50S ribosomal protein L35 -
  ACFIOQ_RS05695 rplT 1096673..1097029 (+) 357 WP_001138360.1 50S ribosomal protein L20 -
  ACFIOQ_RS05700 - 1097171..1097779 (+) 609 WP_000032660.1 NUDIX domain-containing protein -
  ACFIOQ_RS05705 - 1097798..1098727 (+) 930 WP_001280019.1 hypothetical protein -
  ACFIOQ_RS05710 - 1098732..1098842 (+) 111 WP_001790560.1 hypothetical protein -
  ACFIOQ_RS05715 tig 1098890..1100191 (+) 1302 WP_000127565.1 trigger factor -
  ACFIOQ_RS05720 clpX 1100342..1101604 (+) 1263 WP_000472293.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  ACFIOQ_RS05725 yihA 1101758..1102348 (+) 591 WP_000867855.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  ACFIOQ_RS05730 hemA 1102565..1103911 (+) 1347 WP_000545451.1 glutamyl-tRNA reductase -
  ACFIOQ_RS05735 ccsA 1103933..1104748 (+) 816 WP_001157329.1 cytochrome c biogenesis protein -
  ACFIOQ_RS05740 hemC 1104790..1105716 (+) 927 WP_001230227.1 hydroxymethylbilane synthase -
  ACFIOQ_RS05745 - 1105738..1106406 (+) 669 WP_000805957.1 uroporphyrinogen-III synthase -

Sequence

Protein


Download         Length: 420 a.a.        Molecular weight: 46279.44 Da        Isoelectric Point: 4.2645

>NTDB_id=943248 ACFIOQ_RS05720 WP_000472293.1 1100342..1101604(+) (clpX) [Staphylococcus aureus strain t7960]
MFKFNEDEENLKCSFCGKDQDQVKKLVAGSGVYICNECIELCSEIVEEELAQNTSEAITELPTPKEIMDHLNEYVIGQEK
AKKSLAVAVYNHYKRIQQLGPKEDDVELQKSNIALIGPTGSGKTLLAQTLAKTLNVPFAIADATSLTEAGYVGDDVENIL
LRLIQAADFDIDKAEKGIIYVDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPNQEMIQIDTTN
ILFILGGAFDGIEEVIKRRLGEKVIGFSSNEADKYDEQALLAQIRPEDLQAYGLIPEFIGRVPIVANLETLDVTALKNIL
TQPKNALVKQYTKMLELDDVDLEFTEEALSAISEKAIERKTGARGLRSIIEESLIDIMFDVPSNENVTKVVITAQTINEE
TEPELYDAEGNLINNSKTSA

Nucleotide


Download         Length: 1263 bp        

>NTDB_id=943248 ACFIOQ_RS05720 WP_000472293.1 1100342..1101604(+) (clpX) [Staphylococcus aureus strain t7960]
ATGTTTAAATTCAATGAAGATGAAGAAAATTTGAAATGCTCTTTCTGCGGAAAAGACCAAGATCAAGTAAAAAAACTTGT
AGCAGGAAGTGGTGTATATATTTGTAATGAGTGTATTGAATTATGCTCAGAAATCGTCGAAGAAGAATTAGCTCAAAACA
CTTCTGAAGCGATTACAGAATTACCTACTCCTAAAGAAATTATGGATCATTTAAACGAATATGTTATTGGTCAAGAAAAA
GCTAAAAAATCTTTAGCTGTGGCTGTTTATAACCACTATAAGCGTATTCAACAATTAGGACCAAAAGAAGATGATGTTGA
ATTACAAAAAAGTAACATTGCCTTAATTGGTCCAACAGGTAGTGGTAAAACATTATTAGCCCAAACATTAGCCAAGACGT
TGAATGTACCATTTGCAATTGCAGATGCGACAAGTTTAACTGAAGCTGGTTATGTAGGCGATGATGTTGAAAATATCTTG
TTGAGATTAATTCAAGCAGCTGACTTTGACATTGATAAAGCCGAAAAAGGTATTATTTATGTAGATGAAATTGATAAAAT
TGCACGTAAATCTGAAAACACATCTATAACACGTGACGTTTCAGGTGAAGGTGTTCAACAAGCATTGCTTAAAATCTTAG
AAGGTACAACTGCAAGTGTTCCGCCACAAGGTGGACGCAAACATCCAAACCAAGAAATGATTCAAATTGATACAACAAAT
ATCTTATTTATTCTTGGTGGTGCCTTTGATGGTATTGAAGAAGTGATTAAGCGCCGTCTTGGTGAAAAAGTTATTGGTTT
CTCAAGCAATGAAGCTGATAAATATGACGAACAAGCATTATTAGCACAAATTCGCCCAGAAGATTTGCAAGCCTATGGTT
TGATTCCTGAATTTATCGGACGTGTGCCAATTGTAGCTAATTTAGAAACATTAGATGTAACTGCGTTGAAAAACATCTTA
ACGCAACCTAAAAATGCACTTGTGAAACAATATACTAAAATGCTGGAATTAGATGATGTGGATTTAGAGTTCACTGAAGA
AGCTTTATCAGCAATTAGTGAAAAAGCAATTGAAAGAAAAACAGGTGCGCGTGGTTTACGTTCAATCATAGAAGAATCGT
TAATCGATATTATGTTTGATGTGCCTTCTAACGAAAATGTAACGAAGGTAGTTATTACAGCACAAACAATTAATGAAGAA
ACTGAACCAGAACTATACGACGCAGAAGGTAATTTAATTAATAATAGTAAAACATCAGCTTAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-305)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q6GG31

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

66.917

95

0.636
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.456

94.048

0.531