Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   ACFION_RS05565 Genome accession   NZ_CP170399
Coordinates   1087309..1088571 (+) Length   420 a.a.
NCBI ID   WP_000472304.1    Uniprot ID   Q8NW72
Organism   Staphylococcus aureus strain t127     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1082309..1093571
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFION_RS05530 infC 1082837..1083364 (+) 528 WP_001791162.1 translation initiation factor IF-3 -
  ACFION_RS05535 rpmI 1083393..1083593 (+) 201 WP_001125540.1 50S ribosomal protein L35 -
  ACFION_RS05540 rplT 1083640..1083996 (+) 357 WP_001138360.1 50S ribosomal protein L20 -
  ACFION_RS05545 - 1084138..1084746 (+) 609 WP_228567689.1 NUDIX domain-containing protein -
  ACFION_RS05550 - 1084765..1085694 (+) 930 WP_001280022.1 hypothetical protein -
  ACFION_RS05555 - 1085699..1085809 (+) 111 WP_001790560.1 hypothetical protein -
  ACFION_RS05560 tig 1085857..1087158 (+) 1302 WP_000127573.1 trigger factor -
  ACFION_RS05565 clpX 1087309..1088571 (+) 1263 WP_000472304.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  ACFION_RS05570 yihA 1088725..1089315 (+) 591 WP_000867697.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  ACFION_RS05575 hemA 1089532..1090878 (+) 1347 WP_000545451.1 glutamyl-tRNA reductase -
  ACFION_RS05580 ccsA 1090900..1091715 (+) 816 WP_001157329.1 cytochrome c biogenesis protein -
  ACFION_RS05585 hemC 1091757..1092683 (+) 927 WP_001230226.1 hydroxymethylbilane synthase -
  ACFION_RS05590 - 1092705..1093373 (+) 669 WP_000805950.1 uroporphyrinogen-III synthase -

Sequence

Protein


Download         Length: 420 a.a.        Molecular weight: 46296.49 Da        Isoelectric Point: 4.2827

>NTDB_id=943071 ACFION_RS05565 WP_000472304.1 1087309..1088571(+) (clpX) [Staphylococcus aureus strain t127]
MFKFNEDEENLKCSFCGKDQDQVKKLVAGSGVYICNECIELCSEIVEEELAQNTSEAMTELPTPKEIMDHLNEYVIGQEK
AKKSLAVAVYNHYKRIQQLGPKEDDVELQKSNIALIGPTGSGKTLLAQTLAKTLNVPFAIADATSLTEAGYVGDDVENIL
LRLIQAADFDIDKAEKGIIYVDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPNQEMIQIDTTN
ILFILGGAFDGIEEVIKRRLGEKVIGFSSNEADKYDEQALLAQIRPEDLQAYGLIPEFIGRVPIVANLETLDVTALKNIL
TQPKNALVKQYTKMLELDNVDLEFTEEALSAISEKAIERKTGARGLRSIIEESLIDIMFDVPSNENVTKVVITAQTINEE
TEPELYDAEGNLINNSKTSA

Nucleotide


Download         Length: 1263 bp        

>NTDB_id=943071 ACFION_RS05565 WP_000472304.1 1087309..1088571(+) (clpX) [Staphylococcus aureus strain t127]
ATGTTTAAATTCAATGAAGATGAAGAAAATTTGAAATGCTCTTTCTGCGGAAAAGACCAAGATCAAGTAAAAAAACTTGT
AGCAGGAAGTGGTGTATATATTTGTAATGAGTGTATTGAATTATGCTCAGAAATCGTCGAAGAAGAATTAGCTCAAAACA
CTTCTGAAGCGATGACAGAATTACCTACTCCTAAAGAAATTATGGATCATTTAAACGAATATGTTATTGGTCAAGAAAAA
GCTAAAAAATCTTTAGCTGTAGCTGTTTATAACCACTATAAGCGTATTCAACAATTAGGACCAAAAGAAGATGATGTTGA
ATTACAAAAAAGTAACATTGCATTAATTGGGCCAACAGGTAGTGGTAAAACATTATTAGCTCAAACATTAGCCAAGACGT
TGAATGTACCATTTGCAATTGCAGATGCGACAAGTTTAACTGAAGCTGGTTATGTAGGCGATGATGTTGAAAATATCTTG
TTGAGATTAATTCAAGCAGCTGACTTTGACATTGATAAAGCCGAAAAAGGTATTATTTATGTAGATGAAATTGATAAAAT
TGCACGTAAATCTGAAAACACATCTATAACACGTGACGTTTCAGGTGAAGGTGTTCAACAAGCATTGCTTAAAATCTTAG
AAGGTACGACTGCAAGTGTTCCGCCACAAGGTGGACGCAAACATCCAAACCAAGAAATGATTCAAATTGATACAACAAAT
ATCTTATTTATTCTTGGTGGTGCCTTTGATGGTATTGAAGAAGTGATTAAGCGCCGTCTTGGTGAAAAAGTTATTGGTTT
CTCAAGCAATGAAGCTGATAAATATGACGAACAAGCATTATTAGCACAAATTCGCCCAGAAGATTTGCAAGCCTATGGTT
TGATTCCTGAATTTATCGGACGTGTGCCAATTGTAGCTAATTTAGAAACATTAGATGTAACTGCGTTGAAAAACATCTTA
ACGCAACCTAAAAATGCACTTGTGAAACAATATACTAAAATGCTGGAATTAGATAATGTGGATTTAGAGTTCACTGAAGA
AGCTTTATCAGCAATTAGTGAAAAAGCAATTGAAAGAAAAACAGGTGCGCGTGGTTTACGTTCAATCATAGAAGAATCGT
TAATCGATATTATGTTTGATGTGCCTTCTAACGAAAATGTAACGAAGGTAGTTATTACAGCACAAACAATTAATGAAGAA
ACTGAACCAGAACTATACGACGCAGAAGGCAATTTAATTAATAATAGTAAAACATCAGCTTAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-305)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8NW72

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

66.917

95

0.636
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.456

94.048

0.531