Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   V8V48_RS00300 Genome accession   NZ_CP146481
Coordinates   68032..69381 (-) Length   449 a.a.
NCBI ID   WP_412486968.1    Uniprot ID   -
Organism   Staphylococcus xylosus strain MS1     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 65572..74235 68032..69381 within 0


Gene organization within MGE regions


Location: 65572..74235
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V8V48_RS00290 (V8V48_00290) - 65572..65913 (-) 342 WP_073505265.1 SAUGI family uracil-DNA glycosylase inhibitor -
  V8V48_RS00295 (V8V48_00295) ccrB 66384..68012 (-) 1629 WP_412486967.1 cassette chromosome recombinase CcrB Machinery gene
  V8V48_RS00300 (V8V48_00300) ccrA 68032..69381 (-) 1350 WP_412486968.1 cassette chromosome recombinase CcrA Machinery gene
  V8V48_RS00305 (V8V48_00305) - 69552..69815 (-) 264 WP_119646829.1 hypothetical protein -
  V8V48_RS00310 (V8V48_00310) cch1 69881..71671 (-) 1791 WP_326034063.1 cassette chromosome replicative helicase -
  V8V48_RS00315 (V8V48_00315) - 71797..73224 (-) 1428 WP_412486969.1 DUF6038 family protein -
  V8V48_RS00320 (V8V48_00320) - 73485..73703 (+) 219 Protein_61 FAD-binding dehydrogenase -
  V8V48_RS00325 (V8V48_00325) - 73888..74235 (-) 348 WP_075100229.1 MerR family transcriptional regulator -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 52033.91 Da        Isoelectric Point: 10.1015

>NTDB_id=942831 V8V48_RS00300 WP_412486968.1 68032..69381(-) (ccrA) [Staphylococcus xylosus strain MS1]
MKQAIGYLRQSTTKQQSLTAQKQTIEALAEKYSIKHITFYSDKQSGRTDKRNGYQQIIELIQQGKCDVLCCYRLNRLHRN
LKNALKLIKLCQKYNVDIFSVSDGYFDLNKSFDRLKLNIFISLAELESDNIGEQVSNGIKEKARQGKLITTHAPFGYHYY
NGTFVINPGEAQTVTAVFKYYLQGYGYKKIAQYLEKDNKLINRKPYQVRNIIMNPNYCGRVNNKYGTFDNMFPFIISKSV
YKNAQSIRVNKQVQRTPSANLLKQKIKCPCCDSTLTNMTIRKKEHTLRYYVCPKNMNESRFVCSFKGINAQELEVQVLAT
CQNFFQNQQLYSKINNTIHQRLKKQRVIEAKSTLTHEQLIDKLAKGMIDAESFRKQTHSMNQKHKTISSLSDNQLQTSLQ
NVIQKSFTLNMLYPYIDEIHITKNKALVGIYFNNEPLNIVNQTSQLSIA

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=942831 V8V48_RS00300 WP_412486968.1 68032..69381(-) (ccrA) [Staphylococcus xylosus strain MS1]
ATGAAACAAGCAATTGGCTATTTACGTCAAAGTACAACTAAGCAACAATCCCTAACAGCACAGAAACAAACCATCGAGGC
ATTAGCCGAAAAATATAGTATTAAACACATCACTTTTTATAGTGATAAACAATCAGGACGAACTGATAAGCGGAATGGTT
ACCAACAAATTATTGAACTGATTCAACAAGGAAAATGTGATGTATTATGCTGCTATCGACTTAATCGACTACATCGTAAT
TTGAAAAATGCGCTAAAATTAATTAAATTATGCCAGAAGTACAATGTAGATATCTTCAGTGTTAGCGATGGCTATTTTGA
CTTAAACAAATCATTTGATCGTCTAAAACTCAATATCTTCATTTCATTAGCTGAACTTGAGTCAGATAATATTGGTGAAC
AAGTAAGCAACGGAATAAAAGAAAAAGCACGTCAAGGTAAACTAATTACCACACATGCACCTTTTGGATATCATTATTAT
AATGGCACATTTGTAATCAACCCAGGAGAAGCACAAACGGTGACTGCAGTATTCAAATACTATCTTCAAGGGTATGGTTA
CAAAAAGATTGCACAATATTTGGAAAAAGATAATAAGTTAATCAACCGAAAACCATATCAAGTACGTAACATTATTATGA
ACCCTAATTACTGTGGACGTGTGAATAACAAATACGGCACCTTTGATAATATGTTCCCATTTATTATCAGTAAATCAGTG
TATAAAAATGCTCAATCAATACGAGTAAATAAACAAGTTCAGCGCACGCCTTCTGCTAATTTACTCAAACAAAAGATCAA
ATGTCCTTGTTGTGACTCAACACTGACAAATATGACCATAAGAAAAAAAGAACATACATTGCGATATTATGTTTGTCCTA
AAAATATGAATGAATCTCGCTTTGTCTGTTCATTCAAAGGGATAAATGCACAAGAATTAGAAGTTCAAGTCTTAGCTACA
TGTCAGAACTTCTTTCAAAACCAACAGCTCTATTCAAAAATTAATAATACGATTCATCAACGCCTCAAAAAACAAAGAGT
GATAGAAGCTAAAAGTACGCTAACTCACGAACAACTGATAGATAAACTTGCCAAAGGTATGATTGATGCTGAATCATTCA
GAAAACAGACTCATTCGATGAATCAAAAGCACAAAACCATATCCTCCTTAAGTGATAATCAGTTACAAACATCACTACAA
AATGTGATACAGAAAAGTTTCACGTTAAACATGCTGTATCCCTATATTGATGAAATTCATATTACTAAAAACAAAGCCCT
TGTTGGGATCTATTTCAACAATGAACCACTGAACATTGTGAACCAAACCTCGCAATTATCGATTGCCTAA

Domains

Predicted by InterproScan.

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(261-322)

Recombinase (Recombinase)

(170-248)

Resolvase, N terminal domain (Resolvase)

(4-147)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus COL

77.728

100

0.777
  ccrA Staphylococcus aureus N315

70.601

100

0.706