Detailed information NTG0941485

Bioinformatically predicted

Overview

• Name: comGA
• Type: Machinery gene
• Locus tag: V1211_RS06355
• Genome accession: NZ_CP146065
• Coordinates: 1250243..1251217 (+)
• Length: 324 a.a.
• NCBI ID: WP_107612067.1
• Uniprot ID: -
• Organism: Staphylococcus haemolyticus strain SPS12
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1245243..1256217

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V1211_RS06320 (V1211_06330)	rpmG	1245676..1245825 (+)	150	WP_011275661.1	50S ribosomal protein L33	-
V1211_RS06325 (V1211_06335)	-	1246061..1246597 (+)	537	WP_317955335.1	5-formyltetrahydrofolate cyclo-ligase	-
V1211_RS06330 (V1211_06340)	-	1246613..1248070 (+)	1458	WP_317955337.1	rhomboid family intramembrane serine protease	-
V1211_RS06335 (V1211_06345)	-	1248054..1248257 (+)	204	WP_037536577.1	YqgQ family protein	-
V1211_RS06340 (V1211_06350)	-	1248254..1249240 (+)	987	WP_107612069.1	ROK family glucokinase	-
V1211_RS06345 (V1211_06355)	-	1249240..1249563 (+)	324	WP_011275666.1	MTH1187 family thiamine-binding protein	-
V1211_RS06350 (V1211_06360)	-	1249565..1250191 (+)	627	WP_317955339.1	MBL fold metallo-hydrolase	-
V1211_RS06355 (V1211_06365)	comGA	1250243..1251217 (+)	975	WP_107612067.1	competence type IV pilus ATPase ComGA	Machinery gene
V1211_RS06360 (V1211_06370)	comGB	1251189..1252253 (+)	1065	WP_233641399.1	competence type IV pilus assembly protein ComGB	-
V1211_RS06365 (V1211_06375)	comGC	1252267..1252587 (+)	321	WP_107614543.1	competence type IV pilus major pilin ComGC	Machinery gene
V1211_RS06370 (V1211_06380)	comGD	1252652..1253020 (+)	369	WP_326007647.1	competence type IV pilus minor pilin ComGD	-
V1211_RS06375 (V1211_06385)	-	1253868..1254386 (+)	519	WP_107611601.1	shikimate kinase	-
V1211_RS06380 (V1211_06390)	gcvT	1254575..1255666 (+)	1092	WP_037536557.1	glycine cleavage system aminomethyltransferase GcvT	-

Sequence

Protein

• Length: 324 a.a.
• Molecular weight: 37164.13 Da
• Isoelectric Point: 8.2232

>NTDB_id=941485 V1211_RS06355 WP_107612067.1 1250243..1251217(+) (comGA) [Staphylococcus haemolyticus strain SPS12]
MKLLFREIVNKAISKNASDIHFIPSVDEVHIKFRINDYLELYEIFNLDVYQKLLVFMKFKSGLDVSSQQSAQSGRYTYQS
KSTFYLRISTLPLSLGIESCVIRIIPQYFQAKKEYKEFNDFKHLVNKKQGLILLTGPTGSGKSTLMYQMVLHAYKELNLN
VITIENPVEQLLKGITQISINKKAGIDYISSFKAILRCDPDIILIGEIRDAEVAKCVIQASLSGHLVLSTMHSTNCRGAL
LRLLEMGISIQELTQSINIISNQRLITTTQNERRLICETIDKMQIQYFFEHEQTMPHNFNNLEQQLNLLSKEGTICEDTA
SKYF

Nucleotide

• Length: 975 bp

>NTDB_id=941485 V1211_RS06355 WP_107612067.1 1250243..1251217(+) (comGA) [Staphylococcus haemolyticus strain SPS12]
TTGAAACTATTATTCAGAGAGATAGTTAATAAAGCTATTTCAAAAAATGCGAGCGACATACATTTTATCCCTTCAGTTGA
TGAAGTTCATATTAAATTTAGAATTAATGATTACCTTGAACTTTATGAAATATTCAACTTAGATGTATATCAAAAATTAT
TAGTATTTATGAAGTTCAAATCAGGCTTGGACGTTTCATCTCAACAATCCGCTCAAAGTGGTCGTTATACTTATCAATCT
AAATCTACTTTTTATTTACGGATTTCAACATTACCTTTATCTTTAGGTATAGAAAGTTGTGTAATTAGGATAATTCCTCA
ATATTTTCAAGCAAAAAAAGAATATAAAGAATTTAATGATTTTAAACACTTAGTAAATAAAAAGCAGGGATTAATTCTAT
TAACTGGACCCACAGGATCCGGCAAAAGTACTCTAATGTATCAAATGGTTCTACACGCATATAAAGAATTAAATCTTAAT
GTTATCACTATCGAAAACCCAGTTGAGCAATTACTAAAAGGCATTACCCAAATATCAATAAATAAAAAGGCAGGTATAGA
CTACATAAGTTCATTTAAAGCTATATTAAGATGTGATCCTGATATTATTTTAATAGGTGAAATAAGAGACGCAGAAGTTG
CTAAATGTGTTATTCAAGCTAGTTTGAGTGGACATCTTGTATTATCAACCATGCATTCTACTAATTGTAGAGGTGCATTA
CTTCGGTTACTTGAGATGGGAATTTCAATTCAAGAATTAACACAATCTATCAATATCATTTCTAATCAAAGATTAATAAC
GACTACTCAGAATGAGCGTCGCTTAATTTGTGAAACAATAGATAAAATGCAGATACAATATTTCTTCGAGCATGAACAAA
CAATGCCACATAATTTTAATAATTTAGAACAGCAATTAAATTTATTATCTAAAGAAGGAACAATTTGTGAAGATACTGCA
AGTAAATATTTTTAA

Domains

Predicted by InterproScan.

• Type II/IV secretion system protein (T2SSE) (8-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGA	Staphylococcus aureus MW2	65.944	99.691	0.657
comGA	Staphylococcus aureus N315	65.944	99.691	0.657