Detailed information
Bioinformatically predicted
Overview
| Name | amiC | Type | Regulator |
| Locus tag | V6K67_RS08200 | Genome accession | NZ_CP145941 |
| Coordinates | 1584263..1585756 (-) | Length | 497 a.a. |
| NCBI ID | WP_011227407.1 | Uniprot ID | - |
| Organism | Streptococcus thermophilus strain TCI633 | ||
| Function | internalize XIP (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1565784..1637561 | 1584263..1585756 | within | 0 |
Gene organization within MGE regions
Location: 1565784..1637561
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| V6K67_RS08110 (V6K67_08110) | liaF | 1565792..1566490 (-) | 699 | WP_011226289.1 | cell wall-active antibiotics response protein LiaF | - |
| V6K67_RS08115 (V6K67_08115) | - | 1566745..1566912 (-) | 168 | WP_224103618.1 | potassium channel family protein | - |
| V6K67_RS08120 (V6K67_08120) | stkP/pknB | 1567549..1569420 (-) | 1872 | WP_011226292.1 | Stk1 family PASTA domain-containing Ser/Thr kinase | Regulator |
| V6K67_RS08125 (V6K67_08125) | - | 1569420..1570157 (-) | 738 | WP_002946881.1 | Stp1/IreP family PP2C-type Ser/Thr phosphatase | - |
| V6K67_RS08130 (V6K67_08130) | rsmB | 1570201..1571523 (-) | 1323 | WP_014608533.1 | 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB | - |
| V6K67_RS08135 (V6K67_08135) | fmt | 1571513..1572448 (-) | 936 | WP_002951411.1 | methionyl-tRNA formyltransferase | - |
| V6K67_RS08140 (V6K67_08140) | - | 1572466..1574862 (-) | 2397 | WP_011227404.1 | primosomal protein N' | - |
| V6K67_RS08145 (V6K67_08145) | rpoZ | 1575004..1575318 (-) | 315 | WP_002951415.1 | DNA-directed RNA polymerase subunit omega | - |
| V6K67_RS08150 (V6K67_08150) | gmk | 1575340..1575969 (-) | 630 | WP_011226296.1 | guanylate kinase | - |
| V6K67_RS08155 (V6K67_08155) | ftsY | 1576202..1577593 (-) | 1392 | WP_011226297.1 | signal recognition particle-docking protein FtsY | - |
| V6K67_RS08160 (V6K67_08160) | - | 1577607..1578422 (-) | 816 | WP_156703494.1 | Cof-type HAD-IIB family hydrolase | - |
| V6K67_RS08165 (V6K67_08165) | - | 1578415..1579209 (-) | 795 | WP_059257398.1 | HAD family hydrolase | - |
| V6K67_RS08170 (V6K67_08170) | - | 1579393..1579770 (+) | 378 | WP_011226300.1 | GntR family transcriptional regulator | - |
| V6K67_RS08175 (V6K67_08175) | - | 1579775..1580473 (+) | 699 | WP_011226301.1 | ABC transporter ATP-binding protein | - |
| V6K67_RS08180 (V6K67_08180) | - | 1580485..1581270 (+) | 786 | WP_002951425.1 | hypothetical protein | - |
| V6K67_RS08185 (V6K67_08185) | amiF | 1581320..1582249 (-) | 930 | WP_002951426.1 | ATP-binding cassette domain-containing protein | Regulator |
| V6K67_RS08190 (V6K67_08190) | amiE | 1582242..1583327 (-) | 1086 | WP_011226304.1 | ABC transporter ATP-binding protein | Regulator |
| V6K67_RS08195 (V6K67_08195) | amiD | 1583337..1584263 (-) | 927 | WP_002946409.1 | oligopeptide ABC transporter permease OppC | Regulator |
| V6K67_RS08200 (V6K67_08200) | amiC | 1584263..1585756 (-) | 1494 | WP_011227407.1 | ABC transporter permease | Regulator |
| V6K67_RS08205 (V6K67_08205) | amiA | 1585818..1587785 (-) | 1968 | WP_059257397.1 | peptide ABC transporter substrate-binding protein | Regulator |
| V6K67_RS08210 (V6K67_08210) | - | 1588141..1589391 (+) | 1251 | Protein_1567 | ISL3 family transposase | - |
| V6K67_RS08215 (V6K67_08215) | - | 1589436..1591405 (-) | 1970 | Protein_1568 | peptide ABC transporter substrate-binding protein | - |
| V6K67_RS08220 (V6K67_08220) | - | 1591609..1591799 (-) | 191 | Protein_1569 | IS3 family transposase | - |
| V6K67_RS08225 (V6K67_08225) | - | 1591793..1592194 (-) | 402 | Protein_1570 | ABC transporter ATP-binding protein | - |
| V6K67_RS08230 (V6K67_08230) | - | 1592189..1592549 (-) | 361 | Protein_1571 | TatD family hydrolase | - |
| V6K67_RS08235 (V6K67_08235) | - | 1592898..1594103 (+) | 1206 | WP_011227415.1 | OFA family MFS transporter | - |
| V6K67_RS08240 (V6K67_08240) | - | 1594149..1595501 (-) | 1353 | Protein_1573 | IS3 family transposase | - |
| V6K67_RS08245 (V6K67_08245) | pta | 1595587..1596570 (-) | 984 | WP_011227420.1 | phosphate acetyltransferase | - |
| V6K67_RS08250 (V6K67_08250) | - | 1596584..1597480 (-) | 897 | WP_011226316.1 | RluA family pseudouridine synthase | - |
| V6K67_RS08255 (V6K67_08255) | - | 1597477..1598313 (-) | 837 | WP_041827075.1 | NAD kinase | - |
| V6K67_RS08260 (V6K67_08260) | - | 1598285..1598959 (-) | 675 | WP_002951443.1 | GTP pyrophosphokinase family protein | - |
| V6K67_RS08265 (V6K67_08265) | - | 1599055..1599630 (+) | 576 | WP_002951444.1 | CYTH domain-containing protein | - |
| V6K67_RS08270 (V6K67_08270) | - | 1599993..1600964 (+) | 972 | WP_002951446.1 | ribose-phosphate diphosphokinase | - |
| V6K67_RS08275 (V6K67_08275) | - | 1600968..1602080 (+) | 1113 | WP_002948029.1 | cysteine desulfurase family protein | - |
| V6K67_RS08280 (V6K67_08280) | - | 1602082..1602429 (+) | 348 | WP_002948028.1 | DUF1831 domain-containing protein | - |
| V6K67_RS08285 (V6K67_08285) | - | 1602573..1603232 (+) | 660 | WP_041827076.1 | redox-sensing transcriptional repressor Rex | - |
| V6K67_RS08290 (V6K67_08290) | - | 1603225..1603920 (+) | 696 | WP_011227423.1 | gamma-glutamyl-gamma-aminobutyrate hydrolase family protein | - |
| V6K67_RS08295 (V6K67_08295) | radC | 1603973..1604659 (-) | 687 | WP_011227424.1 | DNA repair protein RadC | - |
| V6K67_RS08300 (V6K67_08300) | - | 1604838..1606178 (-) | 1341 | WP_231108743.1 | DUF2142 domain-containing protein | - |
| V6K67_RS08305 (V6K67_08305) | - | 1606327..1608072 (-) | 1746 | WP_011227426.1 | rhamnan synthesis F family protein | - |
| V6K67_RS08310 (V6K67_08310) | - | 1608074..1609774 (-) | 1701 | WP_041827077.1 | glycosyltransferase family 4 protein | - |
| V6K67_RS08315 (V6K67_08315) | - | 1609792..1610994 (-) | 1203 | WP_059257395.1 | ABC transporter ATP-binding protein | - |
| V6K67_RS08320 (V6K67_08320) | - | 1610994..1611800 (-) | 807 | WP_011227429.1 | ABC transporter permease | - |
| V6K67_RS08325 (V6K67_08325) | - | 1611800..1612741 (-) | 942 | WP_011227430.1 | glycosyltransferase family 2 protein | - |
| V6K67_RS08330 (V6K67_08330) | - | 1612738..1613886 (-) | 1149 | WP_011227431.1 | glycosyltransferase family 1 protein | - |
| V6K67_RS08335 (V6K67_08335) | - | 1614005..1614787 (-) | 783 | WP_011227432.1 | glycosyltransferase family A protein | - |
| V6K67_RS08340 (V6K67_08340) | - | 1614788..1615120 (-) | 333 | WP_011227433.1 | DUF2304 domain-containing protein | - |
| V6K67_RS08345 (V6K67_08345) | - | 1615126..1615815 (-) | 690 | WP_011227434.1 | glycosyltransferase family 2 protein | - |
| V6K67_RS08350 (V6K67_08350) | - | 1615917..1616377 (-) | 461 | Protein_1595 | glycosyltransferase family 2 protein | - |
| V6K67_RS08355 (V6K67_08355) | - | 1616442..1617428 (-) | 987 | WP_011227437.1 | glycosyltransferase family 2 protein | - |
| V6K67_RS08360 (V6K67_08360) | - | 1617425..1618684 (-) | 1260 | WP_011227438.1 | lipopolysaccharide biosynthesis protein | - |
| V6K67_RS08365 (V6K67_08365) | rfbD | 1618805..1619656 (-) | 852 | WP_014621820.1 | dTDP-4-dehydrorhamnose reductase | - |
| V6K67_RS08370 (V6K67_08370) | - | 1619774..1620700 (-) | 927 | WP_011227439.1 | glycosyltransferase family 2 protein | - |
| V6K67_RS08375 (V6K67_08375) | - | 1620710..1621045 (-) | 336 | WP_002891474.1 | metal-sulfur cluster assembly factor | - |
| V6K67_RS08380 (V6K67_08380) | rpoD | 1621099..1622208 (-) | 1110 | WP_011227440.1 | RNA polymerase sigma factor RpoD | - |
| V6K67_RS08385 (V6K67_08385) | dnaG | 1622212..1624023 (-) | 1812 | WP_011227441.1 | DNA primase | - |
| V6K67_RS08390 (V6K67_08390) | rpsU | 1624394..1624570 (-) | 177 | WP_011226340.1 | 30S ribosomal protein S21 | - |
| V6K67_RS08395 (V6K67_08395) | - | 1624951..1625904 (+) | 954 | WP_041826943.1 | IS30 family transposase | - |
| V6K67_RS08400 (V6K67_08400) | - | 1626010..1626804 (-) | 795 | WP_011227442.1 | ABC transporter substrate-binding protein | - |
| V6K67_RS08405 (V6K67_08405) | - | 1626897..1628006 (-) | 1110 | WP_041828295.1 | aminotransferase | - |
| V6K67_RS08410 (V6K67_08410) | - | 1628353..1629150 (-) | 798 | WP_059257394.1 | transporter substrate-binding domain-containing protein | - |
| V6K67_RS08415 (V6K67_08415) | - | 1629147..1629977 (-) | 831 | WP_041828297.1 | transporter substrate-binding domain-containing protein | - |
| V6K67_RS08420 (V6K67_08420) | - | 1630191..1630655 (-) | 465 | WP_011226345.1 | 8-oxo-dGTP diphosphatase | - |
| V6K67_RS08425 (V6K67_08425) | uvrB | 1630700..1632691 (-) | 1992 | WP_002953358.1 | excinuclease ABC subunit UvrB | - |
| V6K67_RS08430 (V6K67_08430) | - | 1633378..1634314 (-) | 937 | Protein_1611 | type II CAAX endopeptidase family protein | - |
| V6K67_RS08435 (V6K67_08435) | - | 1634513..1636723 (+) | 2211 | WP_011226350.1 | ABC transporter substrate-binding protein/permease | - |
| V6K67_RS08440 (V6K67_08440) | - | 1636723..1637463 (+) | 741 | WP_002945131.1 | amino acid ABC transporter ATP-binding protein | - |
Sequence
Protein
Download Length: 497 a.a. Molecular weight: 55721.59 Da Isoelectric Point: 10.0618
>NTDB_id=941271 V6K67_RS08200 WP_011227407.1 1584263..1585756(-) (amiC) [Streptococcus thermophilus strain TCI633]
MKKYILLRTLRSLLSIFVVTALTYTIIYTMVPRRLIFRQDPNYNKIAKTADSKANYENTIYERLGYIDYYDTKELQEKAS
SLDKSVTTKPTKENKAIYQKYVDSLGRGWRLHQFKQSKQFYATRDVPVLERVFGFYTHLFEFDNTGWVKDKTNPNLKRYI
RIENDPAIGWSVVGSGTKHKYLLYFNGQFPFVHQNFVKMNLGTSYPTYAEQGVLDVITQGQGQTKSSVVNFPTGKKISSV
DIYSRTYKSPSQADARDRSYYGNDPYTATKSRYQYPSMVTSSAIAGLIGLVLSYALAIPLGSYMALFKNTIFDSVSTGVL
TFLLSLPTIALVYIIRLIGSEIGLPDSFPILGAGDWRSYVLPSVILGLLSTPGLAIWIRRYMIDLQSQDFVRFARAKGLS
EQEISNKHILKNAMVSLVSGIPASIVGVITGATLTETIFAYPGMGKMLIDSVRASNNAMVVGLVFIFTALSIFSLLVGDI
LMTIIDPRIKLTSKGGK
MKKYILLRTLRSLLSIFVVTALTYTIIYTMVPRRLIFRQDPNYNKIAKTADSKANYENTIYERLGYIDYYDTKELQEKAS
SLDKSVTTKPTKENKAIYQKYVDSLGRGWRLHQFKQSKQFYATRDVPVLERVFGFYTHLFEFDNTGWVKDKTNPNLKRYI
RIENDPAIGWSVVGSGTKHKYLLYFNGQFPFVHQNFVKMNLGTSYPTYAEQGVLDVITQGQGQTKSSVVNFPTGKKISSV
DIYSRTYKSPSQADARDRSYYGNDPYTATKSRYQYPSMVTSSAIAGLIGLVLSYALAIPLGSYMALFKNTIFDSVSTGVL
TFLLSLPTIALVYIIRLIGSEIGLPDSFPILGAGDWRSYVLPSVILGLLSTPGLAIWIRRYMIDLQSQDFVRFARAKGLS
EQEISNKHILKNAMVSLVSGIPASIVGVITGATLTETIFAYPGMGKMLIDSVRASNNAMVVGLVFIFTALSIFSLLVGDI
LMTIIDPRIKLTSKGGK
Nucleotide
Download Length: 1494 bp
>NTDB_id=941271 V6K67_RS08200 WP_011227407.1 1584263..1585756(-) (amiC) [Streptococcus thermophilus strain TCI633]
ATGAAAAAATACATTTTATTGAGAACACTCCGTTCTCTATTGTCAATATTTGTCGTGACGGCTTTGACCTACACGATTAT
CTATACCATGGTGCCGAGGCGTCTGATTTTCAGACAAGACCCGAACTACAACAAGATTGCTAAGACAGCTGATTCTAAGG
CTAACTATGAAAATACAATCTATGAACGCTTGGGTTACATTGATTACTATGACACCAAGGAGTTGCAGGAGAAAGCTAGC
TCCCTTGATAAGTCAGTAACCACTAAGCCAACAAAAGAAAATAAGGCTATCTACCAAAAATATGTGGATAGTTTAGGACG
TGGTTGGCGTTTGCATCAGTTCAAGCAAAGTAAACAATTCTATGCGACACGTGATGTGCCAGTGCTTGAACGTGTGTTTG
GCTTCTATACGCACCTCTTTGAATTTGACAATACTGGATGGGTTAAAGATAAAACAAATCCAAACTTGAAGCGTTATATC
CGTATTGAAAATGACCCAGCTATCGGTTGGTCAGTTGTTGGTTCAGGGACTAAGCATAAATATTTGCTTTACTTTAATGG
TCAGTTCCCATTTGTTCACCAAAACTTTGTGAAGATGAACCTTGGTACATCTTACCCAACTTATGCTGAGCAAGGTGTTC
TTGATGTTATTACACAAGGCCAAGGACAGACAAAAAGCTCTGTGGTTAACTTCCCTACTGGTAAGAAAATATCTTCAGTA
GATATCTACTCTCGTACTTATAAATCACCAAGTCAGGCTGACGCTAGAGATCGTTCTTACTATGGAAATGATCCATACAC
AGCTACCAAGAGTCGTTATCAATACCCATCAATGGTGACAAGTTCTGCCATTGCAGGTTTGATTGGTTTGGTCTTGTCTT
ATGCTTTGGCAATTCCATTGGGATCATACATGGCACTCTTTAAAAACACAATCTTTGATAGTGTGTCAACAGGTGTCTTG
ACTTTCTTGCTTTCACTACCAACCATCGCCTTGGTTTATATCATTCGTTTGATTGGTTCTGAGATTGGTCTTCCAGATTC
CTTCCCTATCTTGGGTGCAGGTGACTGGCGTTCATACGTCTTGCCATCTGTTATTCTCGGTCTCTTGTCAACACCAGGTC
TTGCGATTTGGATTCGTCGTTACATGATTGACTTGCAATCACAAGACTTCGTTCGTTTTGCACGTGCCAAAGGGTTGTCA
GAACAAGAAATTTCAAATAAACACATTTTAAAAAACGCTATGGTTTCCTTGGTTTCAGGGATCCCAGCATCTATTGTTGG
GGTTATCACAGGGGCAACCTTGACAGAAACAATCTTCGCCTACCCTGGTATGGGTAAAATGTTGATCGATTCTGTTCGTG
CTTCTAATAATGCTATGGTCGTTGGGCTGGTATTTATTTTTACAGCTCTCTCCATCTTCTCATTGCTTGTGGGTGATATC
CTTATGACTATTATTGACCCACGTATCAAATTGACATCTAAAGGAGGTAAATAA
ATGAAAAAATACATTTTATTGAGAACACTCCGTTCTCTATTGTCAATATTTGTCGTGACGGCTTTGACCTACACGATTAT
CTATACCATGGTGCCGAGGCGTCTGATTTTCAGACAAGACCCGAACTACAACAAGATTGCTAAGACAGCTGATTCTAAGG
CTAACTATGAAAATACAATCTATGAACGCTTGGGTTACATTGATTACTATGACACCAAGGAGTTGCAGGAGAAAGCTAGC
TCCCTTGATAAGTCAGTAACCACTAAGCCAACAAAAGAAAATAAGGCTATCTACCAAAAATATGTGGATAGTTTAGGACG
TGGTTGGCGTTTGCATCAGTTCAAGCAAAGTAAACAATTCTATGCGACACGTGATGTGCCAGTGCTTGAACGTGTGTTTG
GCTTCTATACGCACCTCTTTGAATTTGACAATACTGGATGGGTTAAAGATAAAACAAATCCAAACTTGAAGCGTTATATC
CGTATTGAAAATGACCCAGCTATCGGTTGGTCAGTTGTTGGTTCAGGGACTAAGCATAAATATTTGCTTTACTTTAATGG
TCAGTTCCCATTTGTTCACCAAAACTTTGTGAAGATGAACCTTGGTACATCTTACCCAACTTATGCTGAGCAAGGTGTTC
TTGATGTTATTACACAAGGCCAAGGACAGACAAAAAGCTCTGTGGTTAACTTCCCTACTGGTAAGAAAATATCTTCAGTA
GATATCTACTCTCGTACTTATAAATCACCAAGTCAGGCTGACGCTAGAGATCGTTCTTACTATGGAAATGATCCATACAC
AGCTACCAAGAGTCGTTATCAATACCCATCAATGGTGACAAGTTCTGCCATTGCAGGTTTGATTGGTTTGGTCTTGTCTT
ATGCTTTGGCAATTCCATTGGGATCATACATGGCACTCTTTAAAAACACAATCTTTGATAGTGTGTCAACAGGTGTCTTG
ACTTTCTTGCTTTCACTACCAACCATCGCCTTGGTTTATATCATTCGTTTGATTGGTTCTGAGATTGGTCTTCCAGATTC
CTTCCCTATCTTGGGTGCAGGTGACTGGCGTTCATACGTCTTGCCATCTGTTATTCTCGGTCTCTTGTCAACACCAGGTC
TTGCGATTTGGATTCGTCGTTACATGATTGACTTGCAATCACAAGACTTCGTTCGTTTTGCACGTGCCAAAGGGTTGTCA
GAACAAGAAATTTCAAATAAACACATTTTAAAAAACGCTATGGTTTCCTTGGTTTCAGGGATCCCAGCATCTATTGTTGG
GGTTATCACAGGGGCAACCTTGACAGAAACAATCTTCGCCTACCCTGGTATGGGTAAAATGTTGATCGATTCTGTTCGTG
CTTCTAATAATGCTATGGTCGTTGGGCTGGTATTTATTTTTACAGCTCTCTCCATCTTCTCATTGCTTGTGGGTGATATC
CTTATGACTATTATTGACCCACGTATCAAATTGACATCTAAAGGAGGTAAATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| amiC | Streptococcus thermophilus LMG 18311 |
99.799 |
100 |
0.998 |
| amiC | Streptococcus thermophilus LMD-9 |
99.396 |
100 |
0.994 |
| amiC | Streptococcus salivarius strain HSISS4 |
97.183 |
100 |
0.972 |