Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   V6U70_RS01505 Genome accession   NZ_CP145868
Coordinates   279234..280751 (+) Length   505 a.a.
NCBI ID   WP_410532581.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS12     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 274234..285751
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U70_RS01475 (V6U70_01475) - 274488..274610 (+) 123 Protein_250 energy-coupling factor transporter transmembrane protein EcfT -
  V6U70_RS01480 (V6U70_01480) - 274700..275371 (-) 672 WP_002886585.1 potassium channel family protein -
  V6U70_RS01485 (V6U70_01485) - 275411..276775 (-) 1365 WP_002886586.1 TrkH family potassium uptake protein -
  V6U70_RS01490 (V6U70_01490) rsmG 276844..277557 (-) 714 WP_013990060.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  V6U70_RS01495 (V6U70_01495) - 277856..278392 (+) 537 WP_002883813.1 DUF177 domain-containing protein -
  V6U70_RS01500 (V6U70_01500) covR 278548..279237 (+) 690 WP_002883757.1 response regulator transcription factor Regulator
  V6U70_RS01505 (V6U70_01505) covS 279234..280751 (+) 1518 WP_410532581.1 ATP-binding protein Regulator
  V6U70_RS01510 (V6U70_01510) nrdR 280885..281364 (+) 480 WP_002883820.1 transcriptional regulator NrdR -
  V6U70_RS01515 (V6U70_01515) - 281361..282536 (+) 1176 WP_045771723.1 DnaD domain protein -
  V6U70_RS01520 (V6U70_01520) dnaI 282540..283442 (+) 903 WP_002883792.1 primosomal protein DnaI -
  V6U70_RS01525 (V6U70_01525) der 283547..284857 (+) 1311 WP_002886596.1 ribosome biogenesis GTPase Der -
  V6U70_RS01530 (V6U70_01530) - 284921..285550 (+) 630 WP_225998735.1 glucose-6-phosphate 1-dehydrogenase family protein -

Sequence

Protein


Download         Length: 505 a.a.        Molecular weight: 57601.90 Da        Isoelectric Point: 5.2781

>NTDB_id=940829 V6U70_RS01505 WP_410532581.1 279234..280751(+) (covS) [Streptococcus salivarius strain KSS12]
MSKLQDKLFGKVTIRKKLTMTTAVVFFLVLSMFTLVVIFSANTLLLQRERQNVNTTISKVVTYIEKDWDSDEELSPEPLL
AALYSPKNIYASIINGVLSEKHSLDGQVAISNKLYSNQSVFVYDKKGTFIFTSEENTDSPPGMSEVNKLKSVSYKGKRGF
LLQVPIYGKDKKTIVGYAQIFHDLEFYYALKERLIFLLIFLEVGMTVLVIAATVVVLTSILRPMRQLHETMGVITDSPSD
LELRSKIESHDEIGDLAVNFNRMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHE
ANRMTIMINDMLDSIRVKGSFENHRNDTCDLNSSIRTVIGNFRVLHEDYQFYLNDFESSERPAQIYSQHFEQAITILIDN
AVKYSPVNKEIQVTIKALEDEMLVQVQDNGEGISKEDIEHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCRID
VSSELGVGTRFDLYIPFADGETTTP

Nucleotide


Download         Length: 1518 bp        

>NTDB_id=940829 V6U70_RS01505 WP_410532581.1 279234..280751(+) (covS) [Streptococcus salivarius strain KSS12]
ATGAGTAAATTACAAGATAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTT
TCTTGTATTGTCGATGTTCACTCTGGTTGTTATTTTCTCAGCCAATACGCTACTTTTACAACGTGAACGTCAAAATGTAA
ACACTACAATCTCAAAAGTTGTTACTTATATAGAAAAGGACTGGGACTCCGACGAAGAGTTGAGTCCAGAACCGCTTTTA
GCTGCCCTTTATTCGCCTAAAAATATCTATGCATCGATCATTAATGGCGTGCTTTCCGAAAAGCACTCTTTGGATGGTCA
GGTTGCGATTTCTAATAAATTATATTCTAACCAATCTGTTTTTGTTTATGACAAAAAGGGAACGTTTATCTTTACTTCTG
AGGAGAACACAGATTCGCCTCCAGGTATGTCCGAGGTAAACAAACTGAAGTCAGTTTCCTATAAAGGGAAGCGTGGTTTC
TTGCTACAAGTTCCAATCTACGGTAAAGATAAAAAGACCATCGTTGGTTATGCCCAAATCTTCCATGATTTGGAATTCTA
TTATGCTCTTAAAGAGCGTTTGATTTTCTTATTGATTTTCCTAGAAGTGGGGATGACGGTCCTAGTTATCGCAGCGACTG
TAGTTGTCTTGACATCTATTCTGCGTCCTATGAGACAGTTGCACGAAACGATGGGAGTAATCACCGATTCGCCAAGTGAT
TTGGAACTTCGTTCTAAGATTGAAAGTCACGATGAAATTGGTGATTTGGCGGTTAACTTTAACCGTATGATGGATAAAAT
CCAAGAAAATAATCAGATGCAGATGCGCTTCTTGAGTGACGTCAGTCATGAATTGCGTACACCGATTGCGGTTATCAAGG
GGCATATGGACCTCTTGCAACGTTGGGGTAAAAATGACCCTGAGATTCTTGAGGAAAGTCTTGAGGCTGCCAGTCACGAG
GCCAACCGTATGACGATTATGATTAATGATATGTTGGATTCTATCCGTGTCAAAGGATCATTTGAAAATCACAGAAACGA
TACTTGTGATTTGAATTCTTCAATCCGTACGGTTATTGGTAACTTCCGTGTCTTGCACGAAGACTACCAATTCTATCTCA
ATGATTTCGAGAGCTCAGAGCGCCCTGCACAGATTTACAGCCAACACTTTGAACAGGCGATTACGATTTTGATTGATAAT
GCGGTCAAGTATTCTCCTGTTAACAAGGAAATCCAGGTTACAATTAAGGCTCTGGAAGATGAAATGTTGGTACAAGTACA
AGATAATGGTGAAGGGATCTCTAAAGAAGATATTGAGCATATCTTTGAGCGCTTCTATCGTTCAGATAAGGCACGTAACC
GTACGACAACGCAATCTGGTGTTGGTATTGGTTTGTCAATTCTTTACCAAATTGTGGAAGCTTATCGCTGCCGTATCGAT
GTTAGTTCTGAACTTGGTGTTGGAACACGTTTCGACCTTTACATTCCATTTGCAGATGGAGAAACGACGACACCTTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(274-333)

HAMP domain (HAMP)

(217-269)

ArlS sensor domain (ArlS_N)

(43-191)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(388-497)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

99.802

100

0.998