Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   V6U70_RS01500 Genome accession   NZ_CP145868
Coordinates   278548..279237 (+) Length   229 a.a.
NCBI ID   WP_002883757.1    Uniprot ID   A0AB33ZE44
Organism   Streptococcus salivarius strain KSS12     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 273548..284237
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U70_RS01475 (V6U70_01475) - 274488..274610 (+) 123 Protein_250 energy-coupling factor transporter transmembrane protein EcfT -
  V6U70_RS01480 (V6U70_01480) - 274700..275371 (-) 672 WP_002886585.1 potassium channel family protein -
  V6U70_RS01485 (V6U70_01485) - 275411..276775 (-) 1365 WP_002886586.1 TrkH family potassium uptake protein -
  V6U70_RS01490 (V6U70_01490) rsmG 276844..277557 (-) 714 WP_013990060.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  V6U70_RS01495 (V6U70_01495) - 277856..278392 (+) 537 WP_002883813.1 DUF177 domain-containing protein -
  V6U70_RS01500 (V6U70_01500) covR 278548..279237 (+) 690 WP_002883757.1 response regulator transcription factor Regulator
  V6U70_RS01505 (V6U70_01505) covS 279234..280751 (+) 1518 WP_410532581.1 ATP-binding protein Regulator
  V6U70_RS01510 (V6U70_01510) nrdR 280885..281364 (+) 480 WP_002883820.1 transcriptional regulator NrdR -
  V6U70_RS01515 (V6U70_01515) - 281361..282536 (+) 1176 WP_045771723.1 DnaD domain protein -
  V6U70_RS01520 (V6U70_01520) dnaI 282540..283442 (+) 903 WP_002883792.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26501.51 Da        Isoelectric Point: 4.6354

>NTDB_id=940828 V6U70_RS01500 WP_002883757.1 278548..279237(+) (covR) [Streptococcus salivarius strain KSS12]
MSKRILIVEDEKNLARFVSLELQHEGYDVVTADNGREGLEMALEKDFDLILLDLMLPEMDGFEVTRRLQQEKDTYIMMMT
ARDSIMDIVAGLDRGADDYIVKPFAIEELLARIRATFRRQDIEAAKNAPAKASTYRDLKLDVQNRTVVRGDEAIPLTKRE
FDLLNTLLSNMNQVMTREELLLQVWKYDDAIETNVVDVYIRYLRGKIDVPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 690 bp        

>NTDB_id=940828 V6U70_RS01500 WP_002883757.1 278548..279237(+) (covR) [Streptococcus salivarius strain KSS12]
ATGAGCAAACGCATTTTGATTGTTGAAGATGAGAAAAACCTTGCTCGTTTTGTCTCTCTTGAACTTCAACACGAAGGATA
CGACGTTGTGACAGCAGACAACGGACGCGAAGGACTTGAAATGGCACTCGAGAAAGATTTTGATCTTATTCTCTTGGACC
TTATGTTGCCTGAGATGGACGGTTTTGAAGTAACACGTCGTCTCCAACAAGAAAAAGATACTTATATTATGATGATGACA
GCTCGCGATTCAATCATGGACATTGTTGCTGGTTTGGACCGCGGTGCTGATGACTATATTGTAAAACCATTTGCGATTGA
AGAATTGTTGGCACGTATCCGTGCAACCTTCCGTCGCCAAGATATCGAAGCTGCTAAGAATGCACCAGCAAAAGCATCAA
CTTATCGTGATTTGAAATTGGATGTTCAAAACCGTACAGTTGTTCGTGGTGATGAAGCAATTCCATTGACAAAACGTGAG
TTTGATTTGTTGAACACACTTTTGAGCAATATGAACCAAGTGATGACCCGTGAGGAACTCTTGCTTCAAGTTTGGAAATA
TGATGACGCCATCGAAACAAACGTGGTAGATGTTTATATTCGTTACTTGCGTGGAAAAATCGATGTTCCAGGTAAGGAAT
CATATATTCAAACAGTACGAGGAATGGGTTACGTTATCCGTGAAAAATGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

100

100

1
  covR Lactococcus lactis subsp. lactis strain DGCC12653

68.421

99.563

0.681
  vicR Streptococcus mutans UA159

45.923

100

0.467
  micA Streptococcus pneumoniae Cp1015

44.156

100

0.445