Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   V6U69_RS08430 Genome accession   NZ_CP145867
Coordinates   1836549..1837868 (-) Length   439 a.a.
NCBI ID   WP_155198371.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS10     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1831549..1842868
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U69_RS08420 (V6U69_08415) hpf 1835279..1835827 (-) 549 WP_080611550.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  V6U69_RS08425 (V6U69_08420) - 1835906..1836568 (-) 663 WP_002890024.1 ComF family protein -
  V6U69_RS08430 (V6U69_08425) comFA/cflA 1836549..1837868 (-) 1320 WP_155198371.1 DEAD/DEAH box helicase Machinery gene
  V6U69_RS08435 (V6U69_08430) - 1837923..1838549 (+) 627 WP_155198370.1 YigZ family protein -
  V6U69_RS08440 (V6U69_08435) cysK 1838651..1839577 (+) 927 WP_002883742.1 cysteine synthase A -
  V6U69_RS08445 (V6U69_08440) - 1839725..1840384 (-) 660 WP_002890017.1 CBS and ACT domain-containing protein -
  V6U69_RS08450 (V6U69_08445) - 1840519..1841229 (-) 711 WP_002883761.1 ABC transporter ATP-binding protein -
  V6U69_RS08455 (V6U69_08450) - 1841229..1841993 (-) 765 WP_021143582.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 50622.82 Da        Isoelectric Point: 9.5740

>NTDB_id=940801 V6U69_RS08430 WP_155198371.1 1836549..1837868(-) (comFA/cflA) [Streptococcus salivarius strain KSS10]
MVPKEYYGRLFTKEQLPVNYHPEALTLEGMIKVDKQLRCKRCYSWIEEDWQLPGGQYYCRACIVFGRNQEGKELYYFPSK
TSEIEFPVLKWFGELTPYQAKVSEKLLRTYQKQKDSLVHAVTGAGKTEMIYNIVAYVLENKGHVAIASPRVDVCRELFLR
MKRDFTCSISLLHAESEPYDGSPLVIATTHQLLKFYQSFDLVIVDEVDAYPFVGNVMLNHAVEQAKTETGRFIYLTATST
LSLEEQVRLGALEKHHLARRFHGNPLVLPKFLWQGRLQKSLTRGKLPRPLLYQIKKQRKSKFPLLIFFPNIAIGEKFTSI
LQKYLPDEKMAFVSSKSEERSTIVEKFREKELSILVTTTILERGVTFPQVDVFVCMANHHLYTSSSLIQIGGRVGRSPDR
PTGKLYFFHEGLSKSMLRCREEIKVMNKKGGFNNEVSAM

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=940801 V6U69_RS08430 WP_155198371.1 1836549..1837868(-) (comFA/cflA) [Streptococcus salivarius strain KSS10]
ATGGTACCTAAAGAATATTATGGACGACTATTTACGAAAGAGCAGTTGCCAGTGAACTATCACCCAGAGGCTTTAACATT
AGAAGGTATGATAAAGGTCGATAAACAACTTAGATGTAAAAGATGTTACAGTTGGATAGAGGAAGATTGGCAATTACCGG
GAGGTCAGTATTATTGTAGAGCATGTATTGTCTTTGGTAGAAACCAAGAAGGAAAAGAACTTTATTATTTTCCTTCCAAA
ACATCAGAAATTGAATTTCCTGTTTTGAAGTGGTTTGGAGAATTGACTCCCTATCAAGCTAAGGTCTCAGAGAAACTTTT
GAGAACTTATCAAAAACAGAAAGATAGTCTCGTACATGCTGTGACCGGTGCTGGTAAGACAGAAATGATTTATAACATCG
TTGCCTATGTTCTTGAAAATAAAGGTCATGTAGCTATCGCAAGTCCTAGGGTTGATGTTTGTCGAGAATTATTTCTACGT
ATGAAGAGGGATTTTACTTGTAGTATTTCCCTGCTTCATGCTGAGAGTGAACCATATGATGGTAGTCCGCTTGTAATAGC
TACCACACATCAACTACTAAAGTTTTACCAGAGTTTTGACTTAGTTATTGTAGATGAAGTAGACGCATATCCTTTTGTAG
GAAATGTCATGTTAAATCATGCTGTAGAACAGGCGAAGACCGAAACCGGTCGATTTATTTACTTAACAGCGACTTCAACA
TTATCTTTAGAAGAGCAAGTTCGACTTGGGGCTTTAGAAAAGCATCACCTTGCTAGACGTTTCCATGGAAATCCTTTAGT
ACTTCCTAAATTCCTCTGGCAGGGCAGATTACAAAAATCTCTGACAAGAGGCAAGCTTCCAAGACCTCTTCTTTATCAGA
TTAAAAAGCAACGTAAATCAAAATTTCCTCTATTAATCTTCTTTCCAAATATAGCGATAGGTGAAAAGTTTACAAGTATT
CTACAAAAATATCTTCCAGATGAAAAAATGGCCTTTGTTTCCTCAAAAAGCGAGGAGCGTTCAACTATCGTAGAGAAGTT
CCGAGAAAAAGAACTGTCTATCTTAGTTACAACAACTATCCTCGAACGTGGTGTAACCTTTCCACAAGTAGATGTTTTTG
TTTGTATGGCAAATCATCACTTATACACTAGTTCGAGTCTTATTCAGATTGGAGGTCGAGTTGGAAGATCACCAGATAGA
CCGACAGGAAAGCTTTATTTCTTTCATGAAGGACTATCCAAATCAATGCTTCGGTGTCGAGAAGAGATAAAGGTTATGAA
TAAAAAAGGAGGGTTTAACAATGAAGTGTCTGCTATGTAA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(94-170)

Helicase conserved C-terminal domain (Helicase_C)

(290-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

55.916

98.178

0.549
  comFA/cflA Streptococcus pneumoniae D39

55.916

98.178

0.549
  comFA/cflA Streptococcus pneumoniae R6

55.916

98.178

0.549
  comFA/cflA Streptococcus pneumoniae TIGR4

55.916

98.178

0.549
  comFA/cflA Streptococcus mitis NCTC 12261

55.069

98.861

0.544
  comFA/cflA Streptococcus mitis SK321

54.524

98.178

0.535
  comFA Lactococcus lactis subsp. cremoris KW2

45.952

95.672

0.44
  comFA Latilactobacillus sakei subsp. sakei 23K

37.701

99.089

0.374